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Institution

Tulane University

EducationNew Orleans, Louisiana, United States
About: Tulane University is a education organization based out in New Orleans, Louisiana, United States. It is known for research contribution in the topics: Population & Blood pressure. The organization has 24478 authors who have published 47205 publications receiving 1944993 citations. The organization is also known as: University of Louisiana.


Papers
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Journal ArticleDOI
TL;DR: Three-dimensional high-speed cinematography with computer analysis revealed that the moment acting about the elbow joint to extend the joint through an arc of about 50° was in excess of 600 inch-pounds.
Abstract: Tears of the glenoid labrum were observed in 73 base ball pitchers and other throwing athletes who under went arthroscopic examination of the dominant shoul der. Most of the tears were located over the anterosu perior portion of the glenoid labrum near the origin of the tendon of the long head of the biceps muscle into the glenoid.At arthroscopy, the tendon of the long head of the biceps appeared to originate through and be continuous with the superior portion of the glenoid labrum. In many cases it appeared to have pulled the anterosuperior portion of the labrum off the glenoid. This observation was verified at arthroscopy by viewing the origin of the biceps tendon into the glenoid labrum as the muscle was electrically stimulated. With stimulation of the mus cle, the tendinous portion became quite taut, particu larly near its attachment to the glenoid labrum, and actually lifted the labrum off the glenoid.Three-dimensional high-speed cinematography with computer analysis revealed that the moment acting a...

918 citations

Journal ArticleDOI
15 Jun 2011-JAMA
TL;DR: Elevated FGF-23 is an independent risk factor for end-stage renal disease in patients with relatively preserved kidney function and for mortality across the spectrum of chronic kidney disease.
Abstract: Context A high level of the phosphate-regulating hormone fibroblast growth factor 23 (FGF-23) is associated with mortality in patients with end-stage renal disease, but little is known about its relationship with adverse outcomes in the much larger population of patients with earlier stages of chronic kidney disease. Objective To evaluate FGF-23 as a risk factor for adverse outcomes in patients with chronic kidney disease. Design, Setting, and Participants A prospective study of 3879 participants with chronic kidney disease stages 2 through 4 who enrolled in the Chronic Renal Insufficiency Cohort between June 2003 and September 2008. Main Outcome Measures All-cause mortality and end-stage renal disease. Results At study enrollment, the mean (SD) estimated glomerular filtration rate (GFR) was 42.8 (13.5) mL/min/1.73 m 2 , and the median FGF-23 level was 145.5 RU/mL (interquartile range [IQR], 96-239 reference unit [RU]/mL). During a median follow-up of 3.5 years (IQR, 2.5-4.4 years), 266 participants died (20.3/1000 person-years) and 410 reached end-stage renal disease (33.0/1000 person-years). In adjusted analyses, higher levels of FGF-23 were independently associated with a greater risk of death (hazard ratio [HR], per SD of natural log-transformed FGF-23, 1.5; 95% confidence interval [CI], 1.3-1.7). Mortality risk increased by quartile of FGF-23: the HR was 1.3 (95% CI, 0.8-2.2) for the second quartile, 2.0 (95% CI, 1.2-3.3) for the third quartile, and 3.0 (95% CI, 1.8-5.1) for the fourth quartile. Elevated fibroblast growth factor 23 was independently associated with significantly higher risk of end-stage renal disease among participants with an estimated GFR between 30 and 44 mL/min/1.73 m 2 (HR, 1.3 per SD of FGF-23 natural log-transformed FGF-23; 95% CI, 1.04-1.6) and 45 mL/min/1.73 m 2 or higher (HR, 1.7; 95% CI, 1.1-2.4), but not less than 30 mL/min/1.73 m 2 . Conclusion Elevated FGF-23 is an independent risk factor for end-stage renal disease in patients with relatively preserved kidney function and for mortality across the spectrum of chronic kidney disease.

911 citations

Journal ArticleDOI
TL;DR: Synthetic PACAP27 which shows a considerable homology with vasoactive intestinal polypeptide (VIP) demonstrated a similar vasodepressor activity as VIP, but the adenylate cyclase stimulating activity was about 1000 times greater than VIP.

905 citations

Journal ArticleDOI
TL;DR: Between these different mechanisms, Alu elements have not only contributed a great deal to the evolution of the genome but also continue to contribute to a significant portion of human genetic diseases.

900 citations

Journal ArticleDOI
TL;DR: Idiopathic dilated cardiomyopathy is a primary myocardial disease of unknown cause characterized by left ventricular or biventricular dilatation and impairedMyocardial contractility.
Abstract: Idiopathic dilated cardiomyopathy (IDC) is a primary myocardial disease of unknown cause characterized by left ventricular or biventricular dilatation and impaired myocardial contractility1. Depend...

899 citations


Authors

Showing all 24722 results

NameH-indexPapersCitations
Walter C. Willett3342399413322
JoAnn E. Manson2701819258509
Frank B. Hu2501675253464
Eric B. Rimm196988147119
Krzysztof Matyjaszewski1691431128585
Nicholas J. White1611352104539
Tien Yin Wong1601880131830
Tomas Hökfelt158103395979
Thomas E. Starzl150162591704
Geoffrey Burnstock141148899525
Joseph Sodroski13854277070
Glenn M. Chertow12876482401
Darwin J. Prockop12857687066
Kenneth J. Pienta12767164531
Charles Taylor12674177626
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202388
2022372
20212,622
20202,491
20192,038
20181,795