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Institution

Tulane University

EducationNew Orleans, Louisiana, United States
About: Tulane University is a education organization based out in New Orleans, Louisiana, United States. It is known for research contribution in the topics: Population & Blood pressure. The organization has 24478 authors who have published 47205 publications receiving 1944993 citations. The organization is also known as: University of Louisiana.


Papers
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Journal ArticleDOI
TL;DR: The authors synthesize the expanding corporate social responsibility (CSR) literature from an economic perspective and develop a CSR taxonomy that connects disparate approaches to the subject and explore whether CSR should exist and investigate conditions when CSR may produce higher welfare than other public good provision channels.
Abstract: *This paper synthesizes the expanding corporate social responsibility (CSR) literature. We define CSR from an economic perspective and develop a CSR taxonomy that connects disparate approaches to the subject. We explore whether CSR should exist and investigate conditions when CSR may produce higher welfare than other public good provision channels. We also explore why CSR does exist. Here, we integrate theoretical predictions with empirical findings from economic and noneconomic sources. We find limited systematic empirical evidence in favor of CSR mechanisms related to induced innovation, moral hazard, shareholder preferences, or labor markets. In contrast, we uncover consistent empirical evidence in favor of CSR mechanisms related to consumer markets, private politics, and public politics. (JEL D21, L21, M14)

842 citations

Journal ArticleDOI
TL;DR: In this article, the authors consider the accuracy of projection method approximations to the initial-boundary-value problem for the incompressible Navier-Stokes equations and present an improved projection algorithm which is fully second-order accurate.

841 citations

Journal ArticleDOI
TL;DR: It is argued for the theoretical and practical importance of recovering the correct uniform density limit, which many semiempirical functionals fail to do.
Abstract: We present the case for the nonempirical construction of density functional approximations for the exchange-correlation energy by the traditional method of “constraint satisfaction” without fitting to data sets, and present evidence that this approach has been successful on the first three rungs of “Jacob’s ladder” of density functional approximations [local spin-density approximation (LSD), generalized gradient approximation (GGA), and meta-GGA]. We expect that this approach will also prove successful on the fourth and fifth rungs (hyper-GGA or hybrid and generalized random-phase approximation). In particular, we argue for the theoretical and practical importance of recovering the correct uniform density limit, which many semiempirical functionals fail to do. Among the beyond-LSD functionals now available to users, we recommend the nonempirical Perdew–Burke–Ernzerhof (PBE) GGA and the nonempirical Tao–Perdew–Staroverov–Scuseria (TPSS) meta-GGA, and their one-parameter hybrids with exact exchange. TPSS improvement over PBE is dramatic for atomization energies of molecules and surface energies of solids, and small or moderate for other properties. TPSS is now or soon will be available in standard codes such as GAUSSIAN, TURBOMOLE, NWCHEM, ADF, WIEN, VASP, etc. We also discuss old and new ideas to eliminate the self-interaction error that plagues the functionals on the first three rungs of the ladder, bring up other related issues, and close with a list of “do’s and don’t’s” for software developers and users.

837 citations

Journal ArticleDOI
TL;DR: Most of the metastatic neoplasms had significantly lower genomic m5C contents than did most of the benign neoplasm or normal tissues, which might reflect an involvement of extensive demethylation of DNA in tumor progression.
Abstract: The over-all 5-methylcytosine (m5C) content of DNA from normal tissues varies considerably in a tissue-specific manner. By high-performance liquid chromatography, we have examined the m5C contents of enzymatic digests of DNA from 103 human tumors including benign, primary malignant and secondary malignant neoplasms. The diversity and large number of these tumor samples allowed us to compare the range of DNA methylation levels from neoplastic tissues to that of normal tissues from humans. Most of the metastatic neoplasms had significantly lower genomic m5C contents than did most of the benign neoplasms or normal tissues. The percentage of primary malignancies with hypomethylated DNA was intermediate between those of metastases and benign neoplasms. These findings might reflect an involvement of extensive demethylation of DNA in tumor progression. Such demethylation could be a source of the continually generated cellular diversity associated with cancer.

837 citations


Authors

Showing all 24722 results

NameH-indexPapersCitations
Walter C. Willett3342399413322
JoAnn E. Manson2701819258509
Frank B. Hu2501675253464
Eric B. Rimm196988147119
Krzysztof Matyjaszewski1691431128585
Nicholas J. White1611352104539
Tien Yin Wong1601880131830
Tomas Hökfelt158103395979
Thomas E. Starzl150162591704
Geoffrey Burnstock141148899525
Joseph Sodroski13854277070
Glenn M. Chertow12876482401
Darwin J. Prockop12857687066
Kenneth J. Pienta12767164531
Charles Taylor12674177626
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202388
2022372
20212,622
20202,491
20192,038
20181,795