Tunis University

About: Tunis University is a education organization based out in Tunis, Tunisia. It is known for research contribution in the topics: Population & Thin film. The organization has 11745 authors who have published 15400 publications receiving 154900 citations. The organization is also known as: University of Tunis & UT.

Evaluating the Probiotic Potential of Lactobacillus plantarum Strains from Algerian Infant Feces: Towards the Design of Probiotic Starter Cultures Tailored for Developing Countries.

Abstract: Lactobacilli naturally present in the neonatal gut are believed to be beneficial for the human hosts and are investigated as potential probiotics. In this study, we aimed to characterize six Lactobacillus plantarum strains derived from the feces of a breast-fed infant, for the development of new probiotic cultures. Our attention was focused on L. plantarum in reason of the presence, within such species, of both pro-technological and probiotic strains, i.e., a combination of particular interest to design tailored probiotic starter cultures for developing countries. The bacterial isolates exhibiting lactobacilli-like phenotypic characteristics were identified as members of the L. plantarum group by 16S rRNA gene sequencing, and their diversity was evaluated by randomly amplified polymorphic DNA (RAPD) PCR patterns. The selected strains were screened for probiotic potential through in vitro tests. Firstly, bacterial survival was evaluated in an in vitro system simulating the human oro-gastrointestinal tract, using also milk as a carrier matrix. Besides, physiological traits such as antibiotic susceptibility, antimicrobial activity against selected enteric pathogens, and adhesion to abiotic surfaces and to gastric mucin were studied. Considering the resistance to simulated gastrointestinal digestion and the results from the biofilm and mucin adhesion tests, a strain-denominated L. plantarum LSC3 was selected for further evaluation of in vitro adhesion ability to intestinal mucosa and immunomodulatory activities. L. plantarum LSC3 was able to adhere efficiently to human enterocyte-like cells (Caco-2 cells), and decreased IL-8 transcription while increasing IL-10 mRNA level, as revealed by transcriptional analysis on LPS-stimulated human (THP-1) macrophages. Our results highlight that L. plantarum LSC3 fulfills major in vitro probiotic criteria as well as interesting immunostimulatory properties, and thus may be a promising candidate for further in vivo studies aiming at the development of novel probiotic starter cultures.

Photogrammetric assessment of shoreline retreat in North Africa: Anthropogenic and natural drivers

Abstract: Shoreline retreat along extended semi-arid areas of North African coasts are indicative of the imbalance of coastal sedimentary processes due to modern abrupt changes in precipitation patterns and urban growth. Monitoring of the diachronic shoreline position and land-use from 1952 to 2018 in the coast of the Hammamet Bay in central-east Tunisia, using both aerial and orbital photogrammetric scenes and the Digital Shoreline Analysis System from 1887 to 2018, suggests shoreline retreat rates ranging from −1.3 to −5.6 m/yr. Such rates are abnormal when compared to the average of −0.07 m/yr suggested by global-scale assessment modeling for sandy beach evolution. These abnormal erosions extend over 65 km of sandy beaches, resulting from a severe deficit of sediment transport caused primarily by rapid coastal urban growth that obstructs sediment flow to the shoreline. We suggest that the high retreat rates observed in the low-population period of 1884–1931 originated mainly from storm surges and tsunamis, or potentially subsidence in the coastal substratum. Moreover, our analysis of the salinity of shallow coastal aquifers and land coverage suggests that shoreline retreat coupled with rapid urban growth accelerated seawater intrusion ~5 km inland, causing soil desiccation, the development of salt lakes, and reduction of vegetation coverage by ~18%. These abrupt environmental changes have a severe, adverse impact on crop production and food security in these densely populated and economically important areas across significant parts of the North African coasts, sharing similar key environmental parameters with our study site. We conclude that anthropogenic drivers are the major source of shoreline retreat rather than natural ones.