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Institution

Tunis University

EducationTunis, Tunisia
About: Tunis University is a education organization based out in Tunis, Tunisia. It is known for research contribution in the topics: Population & Thin film. The organization has 11745 authors who have published 15400 publications receiving 154900 citations. The organization is also known as: University of Tunis & UT.


Papers
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Journal ArticleDOI
TL;DR: In this paper, the dispersive and Strichartz inequalities on the Heisenberg group were proved by the analysis of Besov-type spaces on the group, and the results were extended to the general case.
Abstract: In this paper, we prove dispersive and Strichartz inequalities on the Heisenberg group. The proof involves the analysis of Besov-type spaces on the Heisenberg group.

68 citations

Journal ArticleDOI
TL;DR: Key transcripts of the IL-7 receptor (IL-7R) pathway are accumulated in inflamed colon tissues of severe CD and UC patients not responding to either immunosuppressive/corticosteroid, anti-TNF, or anti-α4β7 therapies, and point to IL- 7R as a relevant therapeutic target and potential biomarker to fill an unmet need in clinical IBD detection and treatment.
Abstract: It remains unknown what causes inflammatory bowel disease (IBD), including signaling networks perpetuating chronic gastrointestinal inflammation in Crohn's disease (CD) and ulcerative colitis (UC), in humans. According to an analysis of up to 500 patients with IBD and 100 controls, we report that key transcripts of the IL-7 receptor (IL-7R) pathway are accumulated in inflamed colon tissues of severe CD and UC patients not responding to either immunosuppressive/corticosteroid, anti-TNF, or anti-α4β7 therapies. High expression of both IL7R and IL-7R signaling signature in the colon before treatment is strongly associated with nonresponsiveness to anti-TNF therapy. While in mice IL-7 is known to play a role in systemic inflammation, we found that in humans IL-7 also controlled α4β7 integrin expression and imprinted gut-homing specificity on T cells. IL-7R blockade reduced human T cell homing to the gut and colonic inflammation in vivo in humanized mouse models, and altered effector T cells in colon explants from UC patients grown ex vivo. Our findings show that failure of current treatments for CD and UC is strongly associated with an overexpressed IL-7R signaling pathway and point to IL-7R as a relevant therapeutic target and potential biomarker to fill an unmet need in clinical IBD detection and treatment.

68 citations

Journal ArticleDOI
TL;DR: In this article, the effect of sulfation of vanadia-titania binary solid prepared by sol-gel process on its activity for the selective catalytic reduction (SCR) of NO with NH3 was examined.
Abstract: This paper examines the effect of sulfation of vanadia-titania binary solid prepared by sol-gel process on its activity for the selective catalytic reduction (SCR) of NO with NH3. Sulfated and unsulfated vanadia titania have been characterized by means of N-2 adsorption-desorption at 77 K, XRD, TGA, propan-2-ol conversion as acid test, H-2-TPR measurements, EPR, XPS and Raman spectroscopies. The main results of this study highlight the interaction of sulfate ions with vanadia species. The ternary catalyst VTiS exhibits a high activity compared to binary TiS or VTi samples. It is concluded that sulfate species improve the superficial acidity of solid and interact with vanadia leading to a better reducibility of VTiS oxide. (c) 2006 Elsevier B.V. All rights reserved.

68 citations

Journal ArticleDOI
TL;DR: The efficacy of rituximab in the subset of diffuse SSc in particular in skin and interstitial disease involvements seems to be reasonable and similar to previous data in other autoimmune diseases.

68 citations

Journal ArticleDOI
TL;DR: In this article, a biocomposite sorbent magnetic pine cone gel beads (MPCB) was synthetized and investigated for the single and the simultaneous removal of Cu(II) and Cr(VI) from aqueous solution.

68 citations


Authors

Showing all 11809 results

NameH-indexPapersCitations
Walid Saad8574930499
Alexandre Mebazaa8371639967
Albert Y. Zomaya7594624637
Anis Larbi6725915984
Carmen Torres6446115416
Chedly Abdelly6042914181
Hans R. Kricheldorf5782518670
Mohamed Benbouzid5149212164
Enrique Monte481187868
Fayçal Hentati4715310376
A. D. Roses4512024719
Laurent Nahon452056252
Bessem Samet453087151
Maxim Avdeev425268673
Abdellatif Boudabous401745605
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202316
2022130
20211,621
20201,599
20191,685
20181,689