Uluberia College

About: Uluberia College is a based out in . It is known for research contribution in the topics: Lepton & Space (mathematics). The organization has 31 authors who have published 83 publications receiving 756 citations.

Deformed special relativity and deformed symmetries in a canonical framework

Abstract: In this paper we have studied the nature of kinematical and dynamical laws in $\ensuremath{\kappa}$-Minkowski spacetime from a new perspective: the canonical phase space approach. We discuss a particular form of $\ensuremath{\kappa}$-Minkowski phase space algebra that yields the $\ensuremath{\kappa}$-extended finite Lorentz transformations derived in [D. Kimberly, J. Magueijo, and J. Medeiros, Phys. Rev. D 70, 084007 (2004).]. This is a particular form of a deformed special relativity model that admits a modified energy-momentum dispersion law as well as noncommutative $\ensuremath{\kappa}$-Minkowski phase space. We show that this system can be completely mapped to a set of phase space variables that obey canonical (and not $\ensuremath{\kappa}$-Minkowski) phase space algebra and special relativity Lorentz transformation (and not $\ensuremath{\kappa}$-extended Lorentz transformation). The complete set of deformed symmetry generators are constructed that obeys an unmodified closed algebra but induce deformations in the symmetry transformations of the physical $\ensuremath{\kappa}$-Minkowski phase space variables. Furthermore, we demonstrate the usefulness and simplicity of this approach through a number of phenomenological applications both in classical and quantum mechanics. We also construct a Lagrangian for the $\ensuremath{\kappa}$-particle.

Predicting Gene Expression Level from Relative Codon Usage Bias: An Application to Escherichia coli Genome

Abstract: We present an expression measure of a gene, devised to predict the level of gene expression from relative codon bias (RCB). There are a number of measures currently in use that quantify codon usage in genes. Based on the hypothesis that gene expressivity and codon composition is strongly correlated, RCB has been defined to provide an intuitively meaningful measure of an extent of the codon preference in a gene. We outline a simple approach to assess the strength of RCB (RCBS) in genes as a guide to their likely expression levels and illustrate this with an analysis of Escherichia coli (E. coli) genome. Our efforts to quantitatively predict gene expression levels in E. coli met with a high level of success. Surprisingly, we observe a strong correlation between RCBS and protein length indicating natural selection in favour of the shorter genes to be expressed at higher level. The agreement of our result with high protein abundances, microarray data and radioactive data demonstrates that the genomic expression profile available in our method can be applied in a meaningful way to the study of cell physiology and also for more detailed studies of particular genes of interest.

Citizenship and its discontents: an Indian history

Abstract: Marshall's “Citizenship and Social Class”, where he chronicled the development and growth of citizenship in industrialized societies, especially Britain, has been, for several decades, considered a...

In silico fight against novel coronavirus by finding chromone derivatives as inhibitor of coronavirus main proteases enzyme.

Abstract: Novel coronavirus, 2019-nCoV is a danger to the world and is spreading rapidly. Very little structural information about 2019-nCoV make this situation more difficult for drug designing. Benzylidenechromanones, naturally occurring oxygen heterocyclic compounds, having capability to inhibit various protein and receptors, have been designed here to block mutant variety of coronavirus main protease enzyme (SARC-CoV-2 Mpro) isolated from 2019-nCoV with the assistance of molecular docking, bioinformatics and molecular electrostatic potential. (Z)-3-(4'-chlorobenzylidene)-thiochroman-4-one showed highest binding affinity to the protein. Binding of a compound to this protein actually inhibits the replication and transcription of the virus and, ultimately, stop the virus multiplication. Incorporation of any functional groups to the basic benzylidenechromanones enhances their binding ability. Chloro and bromo substitutions amplify the binding affinity. ADME studies of all these compounds indicate they are lipophilic, high gastro intestine absorbable and blood-brain barrier permeable. The outcome reveals that the investigated benzylidenechromanones can be examined in the case of 2019-nCoV as potent inhibitory drug of SARC-CoV-2 Mpro, for their strong inhibition ability, high reactivity and effective pharmacological properties.