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Institution

United States Environmental Protection Agency

GovernmentWashington D.C., District of Columbia, United States
About: United States Environmental Protection Agency is a government organization based out in Washington D.C., District of Columbia, United States. It is known for research contribution in the topics: Population & Environmental exposure. The organization has 13873 authors who have published 26902 publications receiving 1191729 citations. The organization is also known as: EPA & Environmental Protection Agency.


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Journal ArticleDOI
TL;DR: The Fish and Temperature Database Matching System (FTDMS) as mentioned in this paper has been used to estimate thermal requirements for fishes, some proposed maximum temperature tolerances for several freshwater fish species, and how these FTDMS-derived values relate to various laboratory test results.
Abstract: In 1979, Biesinger et al. described a technique for spatial and temporal matching of records of stream temperatures and fish sampling events to obtain estimates of yearly temperature regimes for freshwater fishes of the United States. This article describes the state of this Fish and Temperature Database Matching System (FTDMS), its usage to estimate thermal requirements for fishes, some proposed maximum temperature tolerances for several freshwater fish species, and the way these FTDMS-derived values relate to various laboratory test results. Although applicable to all species for which collection records exist, initial development and refinement of FTDMS has focused on estimating the maximum weekly mean temperature tolerance for 30 common fishes of the United States. The method involves extensive use of automated data processing during data incorporation, quality assurance checks, data matching, and endpoint calculation. Maximum weekly mean temperatures derived from FTDMS were always less than ...

227 citations

Journal ArticleDOI
TL;DR: In this paper, high metal waste materials from historic mining at the Bunker Hill, Idaho (ID) Superfund site was amended with a range of materials including municipal biosolids, woody debris, wood ash, pulp and paper sludge, and compost.
Abstract: High metal waste materials from historic mining at the Bunker Hill, Idaho (ID) Superfund site was amended with a range of materials including municipal biosolids, woody debris, wood ash, pulp and paper sludge, and compost. The existing soil or waste material has elevated metal concentrations with total Zn, Pb and Cd ranging from 6000 to 14 700, 2100 to 27 000 and 9 to 28 mg kg −1 , respectively. Surface application of certain amendments including biosolids mixed with wood ash resulted in significant decreases in subsoil acidity as well as subsoil extractable metals. This mixture was sufficient to restore a plant cover to the contaminated areas. At the Bunker Hill site, a surface application of high N biosolids (44 or 66 tons ha −1 ) in combination with wood ash (220 tons ha −1 ) with or without log yard debris (20% by volume) or pulp and paper sludge (44 tons ha −1 ) was able to restore a vegetative cover to the metal contaminated materials for 2 years following amendment application. Plant biomass in 1999 was 0.01 mg ha −1 in the control versus a mean of 3.4 tons ha −1 in the residual amended plots. Metal concentrations of the vegetation indicated that plants were within normal concentrations for the 2 years that data were collected. Surface application of amendments was also able to reduce Ca(NO3)2 extractable Zn in the subsoil from about 50 mg kg −1 in the control to less than 4 mg kg −1 in two of the treatments. Use of conventional amendments including lime alone and microbial stimulants were not sufficient to support plant growth. These results indicate that surface application of biosolids in combination with other residuals is sufficient to restore a vegetative cover to high metal mine wastes.

227 citations

Journal ArticleDOI
TL;DR: The data suggest that, at relatively warm Ta's, MDMA-induced stimulation of serotonergic pathways causes an elevation in MR and peripheral vasoconstriction, thus producing life-threatening elevations in Tc, which is consistent with preliminary studies using radiotelemetry methodology.
Abstract: 3,4-Methylenedioxymethamphetamine (MDMA), a substituted amphetamine analogue which stimulates serotonin release in the CNS, has been shown to induce near lethal elevations in core temperature in the rat. To characterize the effects of MDMA on temperature regulation, we measured metabolic rate (MR), evaporative water loss (EWL), motor activity (MA), and colonic temperature (Tc) in male, Long-Evans rats at 60 min following 30 mg/kg (SC) MDMA or saline at ambient temperatures (Ta) of 10, 20, and 30°C. MDMA caused an elevation in MR at Ta's of 20 and 30°C but had no effect at 10°C. At a Ta of 30°C, MR of the MDMA group was double that of the saline group. EWL was elevated by MDMA, an effect which was potentiated with increasing Ta. MDMA also elicited an increase in MA at all three Ta's. MDMA led to a 3.2°C increase in Tc at 30°C, no change in Tc at 20°C, and a 2.0°C decrease in Tc at 10°C. A second study found that treatment with 20 mg/kg MDMA failed to elicit an increase in blood flow to the tail in spite of a hyperthermic core temperature of 41.4°C. Preliminary studies using radiotelemetry methodology suggested that MDMA lethality is preceded by precipitous elevations in heart rate and core temperature. The data suggest that, at relatively warm Ta's, MDMA-induced stimulation of serotonergic pathway causes an elevation in MR and peripheral vasoconstriction, thus producing life-threatening elevations in Tc. The increase in EWL following MDMA partially attenuates the hyperthermia at warm Ta's, but leads to hypothermia in the rat maintained at a cold Ta of 10°C.

227 citations

Journal ArticleDOI
TL;DR: In this paper, metabolic clearance and plasma protein binding were used to parameterize a population-based in vitro-to-in vivo extrapolation model for estimating the human oral equivalent dose necessary to produce a steady-state in vivo concentration equivalent to in vitro AC50 (concentration at 50% of maximum activity) and LEC (lowest effective concentration).

227 citations

Journal ArticleDOI
TL;DR: The concept of emergy defined as the available energy (or exergy) of one form used up directly and indirectly to produce an item or action (Odum, Environmental Accounting Emergy and Environmental Decision Making, John Wiley & Sons, Inc., 1996) requires the specification of a uniform solar equivalent exergy reference.

227 citations


Authors

Showing all 13926 results

NameH-indexPapersCitations
Joel Schwartz1831149109985
Timothy A. Springer167669122421
Chien-Jen Chen12865566360
Matthew W. Gillman12652955835
J. D. Hansen12297576198
Dionysios D. Dionysiou11667548449
John P. Giesy114116262790
Douglas W. Dockery10524457461
Charles P. Gerba10269235871
David A. Savitz9957232947
Stephen Polasky9935459148
Judith C. Chow9642732632
Diane R. Gold9544330717
Scott L. Zeger9537778179
Rajender S. Varma9567237083
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202356
202279
2021780
2020787
2019852
2018929