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Institution

Universidade Católica de Brasília

EducationBrasília, Brazil
About: Universidade Católica de Brasília is a education organization based out in Brasília, Brazil. It is known for research contribution in the topics: Population & Antimicrobial peptides. The organization has 2733 authors who have published 4414 publications receiving 68844 citations.


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Journal ArticleDOI
TL;DR: Findings suggest that a set of general mathematical principles may describe the relations between positive affect and human flourishing.
Abstract: To flourish means to live within an optimal range of human functioning, one that connotes goodness, generativity, growth, and resilience. This definition builds on path-breaking work that measures mental health in positive terms rather than by the absence of mental illness (Keyes, 2002). Flourishing contrasts not just with pathology but also with languishing: a disorder intermediate along the mental health continuum experienced by people who describe their lives as “hollow” or “empty.” Epidemiological work suggests that fewer than 20% of U.S. adults flourish and that the costs of languishing are high; relative to flourishing (and comparable to depression), languishing brings more emotional distress, psychosocial impairment, limitations in daily activities, and lost work days (Keyes, 2002). What predicts whether people will flourish or languish? Are the predictors similar for individuals, relationships, and larger groups? Drawing together existing theory and research on affect and nonlinear dynamic systems, we propose that a key predictor of flourishing is the ratio of positive to negative affect. Over time, and in both private and social contexts, people experience a range of pleasant and unpleasant emotions and moods, and they express a variety of positive and negative evaluative sentiments or attitudes. We use affect to represent this spectrum of valenced feeling states and attitudes, with positive affect and positivity interchangeably representing the pleasant end (e.g., feeling grateful, upbeat; expressing appreciation, liking) and negative affect and negativity representing the unpleasant end (e.g., feeling contemptuous, irritable; expressing disdain, disliking). The affective texture of a person’s life—or of a given relationship or group—can be represented by its positivity ratio, the ratio of pleasant feelings and sentiments to unpleasant ones over time. Past research has shown that for individuals, this ratio predicts subjective well-being (Diener, 2000; Kahneman, 1999). Pushing further, we hypothesize that—for individuals, relationships, and teams—positivity ratios that meet or exceed a certain threshold characterize human flourishing. Although both negative and positive affect can produce adaptive and maladaptive outcomes, a review of the benefits of positive affect provides a particularly useful backdrop for our theorizing.

2,015 citations

Journal ArticleDOI
10 Dec 2010-Science
TL;DR: Though the threat of extinction is increasing, overall declines would have been worse in the absence of conservation, and current conservation efforts remain insufficient to offset the main drivers of biodiversity loss in these groups.
Abstract: Using data for 25,780 species categorized on the International Union for Conservation of Nature Red List, we present an assessment of the status of the world's vertebrates. One-fifth of species are classified as Threatened, and we show that this figure is increasing: On average, 52 species of mammals, birds, and amphibians move one category closer to extinction each year. However, this overall pattern conceals the impact of conservation successes, and we show that the rate of deterioration would have been at least one-fifth again as much in the absence of these. Nonetheless, current conservation efforts remain insufficient to offset the main drivers of biodiversity loss in these groups: agricultural expansion, logging, overexploitation, and invasive alien species.

1,333 citations

Journal ArticleDOI
TL;DR: The goal of this review is to consider the role of nanoscale topographic modification of titanium substrates for the purpose of improving osseointegration and dental implant therapy.

878 citations

Journal ArticleDOI
Alexander Andrew Myburg1, Dario Grattapaglia2, Dario Grattapaglia3, Gerald A. Tuskan4, Gerald A. Tuskan5, Uffe Hellsten4, Richard D. Hayes4, Jane Grimwood6, Jerry Jenkins6, Erika Lindquist4, Hope Tice4, Diane Bauer4, David Goodstein4, Inna Dubchak4, Alexandre Poliakov4, Eshchar Mizrachi1, Anand Raj Kumar Kullan1, Steven G. Hussey1, Desre Pinard1, Karen Van der Merwe1, Pooja Singh1, Ida Van Jaarsveld1, Orzenil B. Silva-Junior3, Roberto C. Togawa3, Marília de Castro Rodrigues Pappas3, Danielle A. Faria3, Carolina Sansaloni3, Cesar Petroli3, Xiaohan Yang5, Priya Ranjan5, Timothy J. Tschaplinski5, Chu-Yu Ye5, Ting Li5, Lieven Sterck7, Kevin Vanneste7, Florent Murat8, Marçal Soler9, Hélène San Clemente9, Naijib Saidi9, Hua Cassan-Wang9, Christophe Dunand9, Charles A. Hefer1, Charles A. Hefer10, Erich Bornberg-Bauer11, Anna R. Kersting11, Anna R. Kersting12, Kelly J. Vining13, Vindhya Amarasinghe13, Martin Ranik13, Sushma Naithani13, Justin Elser13, Alexander Boyd13, Aaron Liston13, Joseph W. Spatafora13, Palitha Dharmwardhana13, Rajani Raja13, Christopher M. Sullivan13, Elisson Romanel14, Elisson Romanel15, Marcio Alves-Ferreira14, Carsten Külheim16, William J. Foley16, Victor Carocha, Jorge A. P. Paiva17, David Kudrna18, Sérgio Hermínio Brommonschenkel19, Giancarlo Pasquali20, Margaret Byrne, Philippe Rigault, Josquin Tibbits21, Antanas V. Spokevicius22, Rebecca C. Jones23, Dorothy A. Steane24, Dorothy A. Steane23, René E. Vaillancourt23, Brad M. Potts23, Fourie Joubert1, Kerrie Barry4, Georgios J. Pappas25, Steven H. Strauss13, Pankaj Jaiswal13, Jacqueline Grima-Pettenati9, Jérôme Salse8, Yves Van de Peer7, Yves Van de Peer1, Daniel S. Rokhsar4, Jeremy Schmutz6, Jeremy Schmutz4 
19 Jun 2014-Nature
TL;DR: Of 36,376 predicted protein-coding genes, 34% occur in tandem duplications, the largest proportion thus far in plant genomes, which shows the highest diversity of genes for specialized metabolites such as terpenes that act as chemical defence and provide unique pharmaceutical oils.
Abstract: Eucalypts are the world's most widely planted hardwood trees. Their outstanding diversity, adaptability and growth have made them a global renewable resource of fibre and energy. We sequenced and assembled >94% of the 640-megabase genome of Eucalyptus grandis. Of 36,376 predicted protein-coding genes, 34% occur in tandem duplications, the largest proportion thus far in plant genomes. Eucalyptus also shows the highest diversity of genes for specialized metabolites such as terpenes that act as chemical defence and provide unique pharmaceutical oils. Genome sequencing of the E. grandis sister species E. globulus and a set of inbred E. grandis tree genomes reveals dynamic genome evolution and hotspots of inbreeding depression. The E. grandis genome is the first reference for the eudicot order Myrtales and is placed here sister to the eurosids. This resource expands our understanding of the unique biology of large woody perennials and provides a powerful tool to accelerate comparative biology, breeding and biotechnology.

679 citations

Journal ArticleDOI
TL;DR: Genomic and metagenomic data predict a number of ecologically relevant capabilities for some acidobacteria, including the ability to: respond to soil macro-, micro nutrients and soil acidity, express multiple active transporters, degrade gellan gum and produce exopolysaccharide (EPS).
Abstract: The phylum Acidobacteria is one of the most widespread and abundant on the planet, yet remarkably our knowledge of the role of these diverse organisms in the functioning of terrestrial ecosystems remains surprisingly rudimentary. This blatant knowledge gap stems to a large degree from the difficulties associated with the cultivation of these bacteria by classical means. Given the phylogenetic breadth of the Acidobacteria, which is similar to the metabolically diverse Proteobacteria, it is clear that detailed and functional descriptions of acidobacterial assemblages are necessary. Fortunately, recent advances are providing a glimpse into the ecology of members of the phylum Acidobacteria. These include novel cultivation and enrichment strategies, genomic characterization and analyses of metagenomic DNA from environmental samples. Here, we couple the data from these complementary approaches for a better understanding of their role in the environment, thereby providing some initial insights into the ecology of this important phylum. All cultured acidobacterial type species are heterotrophic, and members of subdivisions 1, 3, and 4 appear to be more versatile in carbohydrate utilization. Genomic and metagenomic data predict a number of ecologically relevant capabilities for some acidobacteria, including the ability to: use of nitrite as N source, respond to soil macro-, micro nutrients and soil acidity, express multiple active transporters, degrade gellan gum and produce exopolysaccharide (EPS). Although these predicted properties allude to a competitive life style in soil, only very few of these prediction shave been confirmed via physiological studies. The increased availability of genomic and physiological information, coupled to distribution data in field surveys and experiments, should direct future progress in unraveling the ecology of this important but still enigmatic phylum.

629 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20235
202239
2021292
2020306
2019271
2018293