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Institution

Universidade de Pernambuco

EducationRecife, Brazil
About: Universidade de Pernambuco is a education organization based out in Recife, Brazil. It is known for research contribution in the topics: Population & Artificial neural network. The organization has 6147 authors who have published 6948 publications receiving 73648 citations.


Papers
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Journal ArticleDOI
TL;DR: The SDF technique showed better results than IRT for the arrest of cavities in deciduous teeth, indicating that its use for underprivileged communities may justify a paradigm shift in paediatric dentistry.

86 citations

Proceedings ArticleDOI
26 Jul 2009
TL;DR: This article proposes an efficient algorithm to segment handwritten text lines using a morphological operator to obtain the line segmented region of the text.
Abstract: Text extraction is an important phase in document recognition systems. In order to segment text from a page document it is necessary to detect all the possible manuscript text regions. In this article we propose an efficient algorithm to segment handwritten text lines. The text line algorithm uses a morphological operator to obtain the features of the images. Following, a sequence of histogram projection and recovery is proposed to obtain the line segmented region of the text. First, an Y histogram projection is performed which results in the text lines positions. To divide the lines in different regions a threshold is applied. After that, another threshold is used to eliminate false lines. These procedures, however, cause some loss on the text line area. So, a recovery method is proposed to minimize this effect. In order to detect the extreme positions of the text in the horizontal direction, an X histogram projection is applied. Then, as in the Y direction, another threshold is used to eliminate false words. Finally, in order to optimize the area of the manuscript text line, a text selection is carried out. Experimental results using the IAM-database showed that this new approach is robust, fast and produces very good score rates.

86 citations

Journal ArticleDOI
TL;DR: The quantification, antioxidant and antimicrobial activity of capsaicin, dihydrocapsaicin and the flavonoid chrysoeriol isolated from different extracts of Capsicum frutescens (pimenta malagueta) are presented.
Abstract: This paper presents the quantification, antioxidant and antimicrobial activity of capsaicin, dihydrocapsaicin and the flavonoid chrysoeriol isolated from different extracts (hexane and acetonitrile extracts from whole fruit, peel and seed) of Capsicum frutescens (pimenta malagueta). The acetonitrile extract of the seeds, peel and whole fruits contained capsaicin as a major component, followed in abundance by dihydrocapsaicin and chrysoeriol. The antimicrobial activity of the isolated compounds against seven microorganisms showed chrysoeriol was the most active compound. In the antioxidant test, the acetonitrile extract from the whole fruit showed the highest activity. The antioxidant activity of pimenta malagueta may be correlated with its phenolic content, principally with the most active compound, capsaicin.

86 citations

Journal ArticleDOI
TL;DR: A high prevalence of osteoporosis and vertebral fractures in postmenopausal women with type 2 diabetes mellitus, irrespective of blood glucose control, was found, and these conditions were more frequent in long-standing disease and in patients with retinopathy and impaired renal function.
Abstract: Controversial data suggest that patients with type 2 diabetes mellitus have an increased risk of fractures despite having, in some studies, higher bone mineral density. Methods The aim of this study was to determine the prevalence of osteoporosis and morphometric vertebral fractures in 148 postmenopausal diabetic women, aged 61.87±7.85 years, and their relationship with clinical and metabolic factors and chronic complications of the disease. Results The prevalence of osteoporosis was 30.4% at lumbar spine (LS) and 9.5% at femoral neck (FN). The prevalence of vertebral fractures was 23%, mostly mild and located at the thoracic spine. Patients with fractures were older ( P P =.005), had lower creatinine clearance ( P =.026) had and lower bone mineral density at LS ( P =.01) and FN ( P =.042). The frequency of fractures increased with age ( P P =.037) and with the presence of retinopathy ( P =.030). In patients with fractures, the prevalence of osteoporosis increased to 40% at LS ( P =.004) and to 35.7% at FN ( P =.049). After logistic regression adjustment, it was observed that the likelihood of presenting vertebral fractures was significantly increased at the age of 60 years or older ( P P =.006), irrespective of blood glucose control. Conclusion We found a high prevalence of osteoporosis and vertebral fractures in postmenopausal women with type 2 diabetes mellitus, irrespective of blood glucose control, and these conditions were more frequent in long-standing disease and in patients with retinopathy and impaired renal function.

86 citations

Journal ArticleDOI
TL;DR: The mechanisms underlying ZikV infection in the central nervous system require further investigation particularly as there are currently no treatments or vaccines against ZIKV infection.
Abstract: Starting with the outbreak in Brazil, Zika virus (ZIKV) infection has been correlated with severe syndromes such as congenital Zika syndrome and Guillain-Barre syndrome. Here, we review the status of Zika virus pathogenesis in the central nervous system (CNS). One of the main concerns about ZIKV exposure during pregnancy is abnormal brain development, which results in microcephaly in newborns. Recent advances in in vitro research show that ZIKV can infect and obliterate cells from the CNS, such as progenitors, neurons, and glial cells. Neural progenitor cells seem to be the main target of the virus, with infection leading to less cell migration, neurogenesis impairment, cell death and, consequently, microcephaly in newborns. The downsizing of the brain can be directly associated with defective development of the cortical layer. In addition, in vivo investigations in mice reveal that ZIKV can cross the placenta and migrate to fetuses, but with a significant neurotropism, which results in brain damage for the pups. Another finding shows that hydrocephaly is an additional consequence of ZIKV infection, being detected during embryonic and fetal development in mouse, as well as after birth in humans. In spite of the advances in ZIKV research in the last year, the mechanisms underlying ZIKV infection in the CNS require further investigation particularly as there are currently no treatments or vaccines against ZIKV infection.

85 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202314
202261
2021840
2020823
2019571
2018547