Institution
Universidade de Pernambuco
Education•Recife, Brazil•
About: Universidade de Pernambuco is a education organization based out in Recife, Brazil. It is known for research contribution in the topics: Population & Medicine. The organization has 6147 authors who have published 6948 publications receiving 73648 citations.
Papers published on a yearly basis
Papers
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TL;DR: In this article, an integral and in-depth analysis of the evolution of the industrial shrimp farming in Brazil, based on a review of the national political and economic context of the aquaculture activity, and also an evaluation of the environmental impacts of shrimp farming, in the watershed of the Jaguaribe River, Ceara (NE Brazil).
56 citations
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TL;DR: A computational, laboratory-based comparison of the biomechanical stability of 2.0 fixation locking plates with different profiles in Class III atrophic mandibular fractures using 3-dimensional finite element analysis showed large-profile (2.0-mm-thick) locking plates showed better biomechanicals performance than did 1.0 - and 1.5-mm -thick plates.
56 citations
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TL;DR: The primary structure micro heterogeneity was found combining the sequence determination and mass spectrometry, and the SWTI reactive site does not contain the usual Arg or Lys residues at the putative reactive site (position 65).
56 citations
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TL;DR: This review aims to address the strategic role of growth factor therapy in cardiac regeneration, considering its innovative and multifactorial character in myocardial repair after ischemic injury.
Abstract: Myocardial infarction is the most significant manifestation of ischemic heart disease and is associated with high morbidity and mortality. Novel strategies targeting at regenerating the injured myocardium have been investigated, including gene therapy, cell therapy, and the use of growth factors. Growth factor therapy has aroused interest in cardiovascular medicine because of the regeneration mechanisms induced by these biomolecules, including angiogenesis, extracellular matrix remodeling, cardiomyocyte proliferation, stem-cell recruitment, and others. Together, these mechanisms promote myocardial repair and improvement of the cardiac function. This review aims to address the strategic role of growth factor therapy in cardiac regeneration, considering its innovative and multifactorial character in myocardial repair after ischemic injury. Different issues will be discussed, with emphasis on the regeneration mechanisms as a potential therapeutic resource mediated by growth factors, and the challenges to make these proteins therapeutically viable in the field of cardiology and regenerative medicine. Resumo O infarto do miocardio representa a manifestacao mais significativa da cardiopatia isquemica e esta associado a elevada morbimortalidade. Novas estrategias vem sendo investigadas com o intuito de regenerar o miocardio lesionado, incluindo a terapia genica, a terapia celular e a utilizacao de fatores de crescimento. A terapia com fatores de crescimento despertou interesse em medicina cardiovascular, devido aos mecanismos de regeneracao induzidos por essas biomoleculas, incluindo angiogenese, remodelamento da matriz extracelular, proliferacao de cardiomiocitos e recrutamento de celulas-tronco, dentre outros. Em conjunto, tais mecanismos promovem a reparacao do miocardio e a melhora da funcao cardiaca. Esta revisao pretende abordar o papel estrategico da terapia, com fatores de crescimento, para a regeneracao cardiaca, considerando seu carater inovador e multifatorial sobre o reparo do miocardio apos dano isquemico. Diferentes questoes serao discutidas, destacando-se os mecanismos de regeneracao como recurso terapeutico potencial mediado por fatores de crescimento e os desafios para tornar essas proteinas terapeuticamente viaveis no âmbito da cardiologia e da medicina regenerativa.
56 citations
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TL;DR: It is concluded that using arm span as a proxy for height when calculating Body Mass Index is a good indicator of malnutrition and obesity; however, the same was not observed for the overweight.
Abstract: OBJETIVO: Comparar as medidas antropometricas da envergadura e circunferencia braquial para avaliacao do estado nutricional de idosos em relacao ao Indice de Massa Corporal. METODOS: Foram estudados 308 idosos residentes em instituicoes asilares publicas e particulares em Pernambuco, Brasil. RESULTADOS: A sensibilidade do Indice de Massa Corporal, tendo a envergadura como preditora da estatura, no diagnostico da desnutricao, foi de 93,5%, com especificidade de 82,0%. Com relacao ao diagnostico de sobrepeso e obesidade, o calculo do Indice de Massa Corporal, utilizando a envergadura, demonstrou sensibilidade de 44,5% e 83,3% e especificidade de 87,0% e 100,0%, respectivamente. A circunferencia braquial apresentou, no diagnostico de desnutricao, sensibilidade e especificidade de 89,0% e 87,0%, respectivamente. CONCLUSAO: Em idosos, o uso da envergadura em substituicao a altura no calculo do Indice de Massa Corporal, mostrou-se um bom indicador no diagnostico de desnutricao e de obesidade, no entanto nao se observou o mesmo em relacao ao diagnostico de sobrepeso. A medida da circunferencia braquial foi tambem um bom indicador para determinar desnutricao em idosos.
56 citations
Authors
Showing all 6197 results
Name | H-index | Papers | Citations |
---|---|---|---|
Laura C. Rodrigues | 75 | 431 | 21539 |
José Guilherme Cecatti | 56 | 414 | 10550 |
Anibal Faundes | 51 | 314 | 10714 |
Robert E. Condon | 48 | 192 | 7376 |
Ricardo Almeida | 43 | 250 | 7304 |
Mark A. Carlson | 41 | 206 | 7844 |
Ricardo Arraes de Alencar Ximenes | 36 | 181 | 4414 |
Ivan G. Costa | 36 | 129 | 3740 |
Tshilidzi Marwala | 35 | 525 | 5596 |
Cláudia Lúcia de Moraes Forjaz | 34 | 202 | 4549 |
Nelson Wolosker | 33 | 348 | 4416 |
Raphael Mendes Ritti-Dias | 32 | 277 | 11334 |
Marcelo Moraes Valença | 32 | 207 | 3702 |
Mauro Virgílio Gomes de Barros | 32 | 163 | 8608 |
Rômulo Araújo Fernandes | 31 | 290 | 6403 |