Institution
Universidade Estadual de Londrina
Education•Londrina, Brazil•
About: Universidade Estadual de Londrina is a education organization based out in Londrina, Brazil. It is known for research contribution in the topics: Population & Toxoplasma gondii. The organization has 13052 authors who have published 19291 publications receiving 212123 citations.
Topics: Population, Toxoplasma gondii, Oxidative stress, Starch, Germination
Papers published on a yearly basis
Papers
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Luis M. P. Ceríaco1, Luis M. P. Ceríaco2, Eliécer E. Gutiérrez3, Eliécer E. Gutiérrez4 +491 more•Institutions (168)
TL;DR: The question whether taxonomic descriptions naming new animal species without type specimen(s) deposited in collections should be accepted for publication by scientific journals and allowed by the Code has already been discussed in Zootaxa.
Abstract: The question whether taxonomic descriptions naming new animal species without type specimen(s) deposited in collections should be accepted for publication by scientific journals and allowed by the Code has already been discussed in Zootaxa (Dubois & Nemesio 2007; Donegan 2008, 2009; Nemesio 2009a–b; Dubois 2009; Gentile & Snell 2009; Minelli 2009; Cianferoni & Bartolozzi 2016; Amorim et al. 2016). This question was again raised in a letter supported by 35 signatories published in the journal Nature (Pape et al. 2016) on 15 September 2016. On 25 September 2016, the following rebuttal (strictly limited to 300 words as per the editorial rules of Nature) was submitted to Nature, which on 18 October 2016 refused to publish it. As we think this problem is a very important one for zoological taxonomy, this text is published here exactly as submitted to Nature, followed by the list of the 493 taxonomists and collection-based researchers who signed it in the short time span from 20 September to 6 October 2016.
59 citations
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TL;DR: This is the first report of the anti-trypanosomal effect of the sesquiterpene elatol from the Brazilian red seaweed Laurencia dendroidea, and Transmission and scanning electron micrographs showed aberrant-shaped cells and breaks in the plasma membrane, prominent swollen mitochondria, and extensive formation of cytoplasmic vacuoles in all the forms.
Abstract: Chagas' disease is a debilitating but comparatively neglected illness that affects about 15 million people. There is an urgent need to develop new, more effective, and less-toxic compounds. In this study, we assessed the in vitro anti-trypanosomal activity of the sesquiterpene elatol from the Brazilian red seaweed Laurencia dendroidea. We used electron microscopy to evaluate the effect of elatol on the morphology and ultrastructure of the parasite. Elatol showed a dose-dependent effect against the epimastigote, trypomastigote, and amastigote forms, with IC50 values of 45·4, 1·38, and 1·01 μm, respectively. Observation of treated intracellular amastigotes by light microscopy demonstrated a total elimination of the infection at a dose of 3·0 μm. In addition, the compound did not affect the red blood cells, and the CC50 value for LLCMK2 cells was 27·0 μm. Transmission and scanning electron micrographs showed aberrant-shaped cells and breaks in the plasma membrane, prominent swollen mitochondria, and extensive formation of cytoplasmic vacuoles in all the forms. This is the first report of the anti-trypanosomal effect of the sesquiterpene elatol.
59 citations
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TL;DR: There were no differences between the Pilates and general exercises with regard to pain and functionality in NSCLBP subjects but general exercises were better than Pilates for increasing functionality and flexibility.
59 citations
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TL;DR: An indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) based on an anti-aflatoxin B 1 monoclonal antibody was standardised and validated for aflatoxin screening in poultry feed samples and its performance was compared to high-performance liquid chromatography (HPLC) as discussed by the authors.
59 citations
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TL;DR: The present data support the potential effect of this class of compounds against T. cruzi and encourage further experiments in vitro to evaluate the action mechanism of this drug and also with in vivo models.
59 citations
Authors
Showing all 13138 results
Name | H-index | Papers | Citations |
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Michael Maes | 115 | 807 | 52050 |
Fernando Q. Cunha | 88 | 682 | 31501 |
Mariangela Hungria | 67 | 389 | 15219 |
Petar Popovski | 59 | 756 | 21009 |
Waldiceu A. Verri | 54 | 249 | 10311 |
Thiago M. Cunha | 54 | 268 | 9519 |
Emerson Franchini | 52 | 402 | 9620 |
Celso Vataru Nakamura | 51 | 418 | 10908 |
Diego Augusto Santos Silva | 51 | 389 | 53077 |
Susan M. Tarlo | 50 | 263 | 10850 |
Paulo Caramelli | 45 | 366 | 9666 |
Fabio Pitta | 44 | 213 | 11925 |
Joaquim Gama-Rodrigues | 43 | 225 | 8380 |
Ricardo Almeida | 43 | 250 | 7304 |
Hamilton Roschel | 43 | 235 | 5894 |