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Institution

Universidade Estadual de Londrina

EducationLondrina, Brazil
About: Universidade Estadual de Londrina is a education organization based out in Londrina, Brazil. It is known for research contribution in the topics: Population & Toxoplasma gondii. The organization has 13052 authors who have published 19291 publications receiving 212123 citations.


Papers
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Journal ArticleDOI
TL;DR: It is suggested that MDA may serve as a disease biomarker, while LOOH and SOD activity are associated with late PD stage characteristic, while new treatments for PD should not only target dopamine but also lipid peroxidation.

89 citations

Journal ArticleDOI
TL;DR: Rutin was tested against the pro-carcinogenic agent benzo(a)pyrene, at concentrations of 90, 270 and 810 μM, and was found to reduce induced DNA damage significantly, suggesting an important biological activity for this compound, which can contribute to human health through the diet.

88 citations

Journal ArticleDOI
TL;DR: Evidence is provided of quantitative and qualitative differences in the oxidative stress generated by chronological aging and photoaging of the skin in HRS/J hairless mice that represent a potential new approach to understanding the phenomenon of skin aging and a new target for therapeutic intervention.
Abstract: The impact of chronological aging and photoaging on the skin is particularly concerning, especially when oxidative stress is involved. This article provides evidence of quantitative and qualitative differences in the oxidative stress generated by chronological aging and photoaging of the skin in HRS/J hairless mice. Analysis of the results revealed an increase in lipid peroxides as the skin gets older and in photoaged skin (10.086 ± 0.70 η MDA/mg and 14.303 ± 1.81 η MDA/mg protein, respectively), although protein oxidation was only verified in chronological aged skin (15.449 ± 0.99 η protein/mg protein). The difference between both skin types is the decay in the capacity of lipid membrane turnover revealed by the dislocation of older skin to the left in the chemiluminescence curve. Imbalance between antioxidant and oxidation processes was verified by the decrease in total antioxidant capacity of chronological and photoaged skins. Although superoxide dismutase remained unchanged, catalase increased in the 18 and 48-week-old skin groups and decreased in irradiated mice, demonstrating that neither enzyme is a good parameter to determine oxidative stress. The differences observed between chronological and photoaging skin represent a potential new approach to understanding the phenomenon of skin aging and a new target for therapeutic intervention.

88 citations

Journal ArticleDOI
TL;DR: A survey of the estimated costs of soil erosion, an issue of fundamental importance in view of the current worldwide discussions on sustainability, is presented in this paper, where a list was drawn up of research papers on erosion and their respective costs.
Abstract: The aim of this study was a survey of the estimated costs of soil erosion, an issue of fundamental importance in view of the current worldwide discussions on sustainability. A list was drawn up of research papers on erosion (on-site and offsite effects) and their respective costs. The estimates indicate the amount of resources spent in the process of soil degradation, raising a general awareness of the need for soil conservation. On-site costs affect the production units directly, while off-site costs create a burden borne by the environment, economy and society. In addition, estimating the costs of soil erosion should be effective to alert the agricultural producers, society and government for the need for measures that can be implemented to bring erosion under control. Among the various estimates of soil erosion costs between 1933 a 2010, the highest figure was 45.5 billion dollars a year for the European Union. In the United States, the highest figure was 44 billion dollars a year. In Brazil, estimates for the state of Parana indicate a value of 242 million dollars a year, and for the state of Sao Paulo, 212 million dollars a year. These figures show, above all, that conservation measures must be implemented if crop and livestock farming production are to be sustainable.

88 citations

Journal ArticleDOI
TL;DR: In both patients with COPD and healthy elderly, the multisensor showed better EE estimates during most walking speeds than the pedometer, and for step counting, accuracy is observed only with the pedometers during the higher walking speed in both groups.

87 citations


Authors

Showing all 13138 results

NameH-indexPapersCitations
Michael Maes11580752050
Fernando Q. Cunha8868231501
Mariangela Hungria6738915219
Petar Popovski5975621009
Waldiceu A. Verri5424910311
Thiago M. Cunha542689519
Emerson Franchini524029620
Celso Vataru Nakamura5141810908
Diego Augusto Santos Silva5138953077
Susan M. Tarlo5026310850
Paulo Caramelli453669666
Fabio Pitta4421311925
Joaquim Gama-Rodrigues432258380
Ricardo Almeida432507304
Hamilton Roschel432355894
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202324
2022151
20211,220
20201,433
20191,333
20181,308