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Institution

Universidade Federal de Minas Gerais

EducationBelo Horizonte, Minas Gerais, Brazil
About: Universidade Federal de Minas Gerais is a education organization based out in Belo Horizonte, Minas Gerais, Brazil. It is known for research contribution in the topics: Population & Immune system. The organization has 41631 authors who have published 75688 publications receiving 1249905 citations.


Papers
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Journal ArticleDOI
TL;DR: In this paper, a pedagogical introduction to self-organized criticality (SOC) is presented, which unravels its connections with nonequilibrium phase transitions, showing that SOC is a consequence of slow driving in a system exhibiting an absorbing-state phase transition with a conserved density.
Abstract: We present a pedagogical introduction to self-organized criticality (SOC), unraveling its connections with nonequilibrium phase transitions. There are several paths from a conventional critical point to SOC. They begin with an absorbing-state phase transition (directed percolation is a familiar example), and impose supervision or driving on the system; two commonly used methods are extremal dynamics, and driving at a rate approaching zero. We illustrate this in sandpiles, where SOC is a consequence of slow driving in a system exhibiting an absorbing-state phase transition with a conserved density. Other paths to SOC, in driven interfaces, the Bak-Sneppen model, and self- organized directed percolation, are also examined. We review the status of experimental realizations of SOC in light of these observations.

291 citations

Journal ArticleDOI
TL;DR: In this article, the authors investigate the accretion and outflow dynamics and their interaction from observations of the classical T T Tauri star AA Tau, and they find that most spectral and photometric diagnostics vary as expected from models of magnetically-channelled accretion in young stars, with a large scale magnetosphere tilted by 20 degrees onto the star spin axis.
Abstract: Context. Accretion and ejection are complex and related processes that vary on various timescales in young stars. Aims. We intend to investigate the accretion and outflow dynamics and their interaction from observations of the classical T Tauri star AA Tau. Methods. From a long time series of high resolution (R = 115 000) HARPS spectra and simultaneous broad-band photometry, we report new evidence for magnetospheric accretion as well as ejection processes in the nearly edge-on classical T Tauri star AA Tau. Results. AA Tau’s light curve is modulated with a period of 8.22 d. The recurrent luminosity dips are due to the periodic occultation of the central star by the magnetically-warped inner disk edge located at about 9 R� . Balmer line profiles exhibit a clear rotational modulation of high-velocity redshifted absorption components with a period of 8.22 days as well, with a maximum strength when the main accretion funnel flow passes through the line of sight. At the same time, the luminosity of the system decreases by about 1 mag, indicative of circumstellar absorption of the stellar photosphere by the magnetically-warped, corotating inner disk edge. The photospheric and He I radial velocities also exhibit periodic variations, and the veiling is modulated by the appearance of the accretion shock at the bottom of the accretion funnel. Diagnostics of hot winds and their temporal behaviour are also presented. Conclusions. The peculiar geometry of the young AA Tau system (nearly edge-on) allows us to uniquely probe the acretion-ejection region close to the star. We find that most spectral and photometric diagnostics vary as expected from models of magneticallychannelled accretion in young stars, with a large scale magnetosphere tilted by 20 ◦ onto the star’s spin axis. We also find evidence for time variability of the magnetospheric accretion flow on a timescale of a few rotational periods.

291 citations

Journal ArticleDOI
TL;DR: The aim of the present minireview was to summarize the pathophysiological mechanism and the main risk factors for AD, and some protective factors associated with a lower risk of disease incidence, such as cognitive reserve, physical activity and diet will also be addressed.
Abstract: Alzheimer’s disease (AD) is the most common type of dementia and typically manifests through a progressive loss of episodic memory and cognitive function, subsequently causing language and visuospatial skills deficiencies, which are often accompanied by behavioral disorders such as apathy, aggressiveness and depression. The presence of extracellular plaques of insoluble β-amyloid peptide (Aβ) and neurofibrillary tangles (NFT) containing hyperphosphorylated tau protein (P-tau) in the neuronal cytoplasm is a remarkable pathophysiological cause in patients’ brains. Approximately 70% of the risk of developing AD can be attributed to genetics. However, acquired factors such as cerebrovascular diseases, diabetes, hypertension, obesity and dyslipidemia increase the risk of AD development. The aim of the present minireview was to summarize the pathophysiological mechanism and the main risk factors for AD. As a complement, some protective factors associated with a lower risk of disease incidence, such as cognitive reserve, physical activity and diet will also be addressed.

290 citations


Authors

Showing all 42077 results

NameH-indexPapersCitations
Michael Marmot1931147170338
Pulickel M. Ajayan1761223136241
Alan D. Lopez172863259291
Jens Nielsen1491752104005
Mildred S. Dresselhaus136762112525
Jing Kong12655372354
Mauricio Terrones11876061202
Michael Brammer11842446763
Terence G. Langdon117115861603
Caroline A. Sabin10869044233
Michael Brauer10648073664
Michael Bader10373537525
Michael S. Strano9848060141
Pablo Jarillo-Herrero9124539171
Riichiro Saito9150248869
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023111
2022624
20215,708
20205,955
20195,269
20185,020