Universidade Federal de Minas Gerais

About: Universidade Federal de Minas Gerais is a education organization based out in Belo Horizonte, Minas Gerais, Brazil. It is known for research contribution in the topics: Population & Immune system. The organization has 41631 authors who have published 75688 publications receiving 1249905 citations.

Current issues in the presentation of asymptomatic primary hyperparathyroidism: proceedings of the Fourth International Workshop

Abstract: Objective: This report summarizes data on traditional and nontraditional manifestations of primary hyperparathyroidism (PHPT) that have been published since the last International Workshop on PHPT. Participants: This subgroup was constituted by the Steering Committee to address key questions related to the presentation of PHPT. Consensus was established at a closed meeting of the Expert Panel that followed. Evidence: Data from the 5-year period between 2008 and 2013 were presented and discussed to determine whether they support changes in recommendations for surgery or nonsurgical follow-up. Consensus Process: Questions were developed by the International Task Force on PHPT. A comprehensive literature search for relevant studies was undertaken. After extensive review and discussion, the subgroup came to agreement on what changes in the recommendations for surgery or nonsurgical follow-up of asymptomatic PHPT should be made to the Expert Panel. Conclusions: 1) There are limited new data available on the na...

Ages of detrital zircon from Archean-Paleoproterozoic sequences: Implications for Greenstone Belt setting and evolution of a Transamazonian foreland basin in Quadrilátero Ferrífero, southeast Brazil

Abstract: The Sao Francisco shield is one of the major cratonic units forming the backbone of the South American continent. The Quadrilatero Ferrifero area, in the south of the shield, is underlain by three major units: granitic-gneissic terrains with a minimum age of 2860 Ma; the Rio das Velhas greenstone belt, emplaced at 2772–2780 Ma; and the Minas Supergroup-Itacolomi Group Paleoproterozoic sedimentary sequences. The 207 Pb 206 Pb and UPb ages of more than 400 detrital zircons obtained by Laser ablation-ICPMS and isotope dilution lead to the following conclusions: (1) the Rio das Velhas greenstone belt contains exclusively cratogenic sediments and developed on, or proximal to, old, evolved continental crust with a minimum age of ca. 2.85 Ga; (2) the lower detrital sequence of the Minas Supergroup was supplied with sediments derived from both the granite-greenstone terrain and the surrounding older crust; (3) the upper unit of the Minas Supergroup (Sabara Formation) contains 2125 Ma zircon and the overlying Itacolomi Group contain zircons with minimum ages of ca. 2.06 Ga, identical to the ages of regional metamorphism. Together with other considerations, these ages lead to the novel proposal that the tectogenic sedimentation represented by these units occurred in a foreland basin of the Transamazonian orogen. Basin evolution was closely associated with the tectonic development of the orogen and uplift of basement complexes between 2125 Ma and 2030 Ma. The scarcity of 2.6-2.4 Ga zircons in the Proterozoic units of the Quadrilatero Ferrifero confirms previous results for the Sao Francisco shield and is symptomatic of the absence of magmatic-metamorphic activity in that period of time.

Pressure Routing for Underwater Sensor Networks

Abstract: A SEA Swarm (Sensor Equipped Aquatic Swarm) is a sensor "cloud" that drifts with water currents and enables 4D (space and time) monitoring of local underwater events such as contaminants, marine life and intruders. The swarm is escorted at the surface by drifting sonobuoys that collect the data from underwater sensors via acoustic modems and report it in real-time via radio to a monitoring center. The goal of this study is to design an efficient anycast routing algorithm for reliable underwater sensor event reporting to any one of the surface sonobuoys. Major challenges are the ocean current and the limited resources (bandwidth and energy). In this paper, we address these challenges and propose HydroCast, a hydraulic pressure based anycast routing protocol that exploits the measured pressure levels to route data to surface buoys. The paper makes the following contributions: a novel opportunistic routing mechanism to select the subset of forwarders that maximizes greedy progress yet limiting co-channel interference; and an efficient underwater "dead end" recovery method that outperforms recently proposed approaches. The proposed routing protocols are validated via extensive simulations.

Ancestral genomes, sex, and the population structure of Trypanosoma cruzi.

Abstract: Acquisition of detailed knowledge of the structure and evolution of Trypanosoma cruzi populations is essential for control of Chagas disease. We profiled 75 strains of the parasite with five nuclear microsatellite loci, 24Sα RNA genes, and sequence polymorphisms in the mitochondrial cytochrome oxidase subunit II gene. We also used sequences available in GenBank for the mitochondrial genes cytochrome B and NADH dehydrogenase subunit 1. A multidimensional scaling plot (MDS) based in microsatellite data divided the parasites into four clusters corresponding to T. cruzi I (MDS-cluster A), T. cruzi II (MDS-cluster C), a third group of T. cruzi strains (MDS-cluster B), and hybrid strains (MDS-cluster BH). The first two clusters matched respectively mitochondrial clades A and C, while the other two belonged to mitochondrial clade B. The 24Sα rDNA and microsatellite profiling data were combined into multilocus genotypes that were analyzed by the haplotype reconstruction program PHASE. We identified 141 haplotypes that were clearly distributed into three haplogroups (X, Y, and Z). All strains belonging to T. cruzi I (MDS-cluster A) were Z/Z, the T. cruzi II strains (MDS-cluster C) were Y/Y, and those belonging to MDS-cluster B (unclassified T. cruzi) had X/X haplogroup genotypes. The strains grouped in the MDS-cluster BH were X/Y, confirming their hybrid character. Based on these results we propose the following minimal scenario for T. cruzi evolution. In a distant past there were at a minimum three ancestral lineages that we may call, respectively, T. cruzi I, T. cruzi II, and T. cruzi III. At least two hybridization events involving T. cruzi II and T. cruzi III produced evolutionarily viable progeny. In both events, the mitochondrial recipient (as identified by the mitochondrial clade of the hybrid strains) was T. cruzi II and the mitochondrial donor was T. cruzi III.