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Institution

Universidade Federal de Minas Gerais

EducationBelo Horizonte, Minas Gerais, Brazil
About: Universidade Federal de Minas Gerais is a education organization based out in Belo Horizonte, Minas Gerais, Brazil. It is known for research contribution in the topics: Population & Immune system. The organization has 41631 authors who have published 75688 publications receiving 1249905 citations.


Papers
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Journal ArticleDOI
TL;DR: Under appropriate conditions, IL-12 has therapeutic efficacy for promoting defense against a variety of pathogens, and for use as a vaccine adjuvant to enhance beneficial Th1 over detrimental Th2 lymphocyte responses.

234 citations

Journal ArticleDOI
TL;DR: With one of the world's largest public health systems in terms of population coverage, Brazil has the means to implement actions to confront the high burden of CVD, focusing on health promotion and comprehensive care.
Abstract: Brazil is a large country, with an evolving economy, but marked social inequalities. The population is formed by an admixture of native Brazilians, Europeans, and Africans; is predominantly urban; and faces rapid aging. Time trends related to health behaviors show a substantial reduction in smoking rates, but a rising prevalence of overweight and obesity, unhealthy eating habits, and insufficient physical activity. The high prevalence of hypertension and the increasing prevalence of diabetes mellitus are also causes for concern. Cardiovascular disease (CVD) has been the leading cause of mortality since the 1960s and has accounted for a substantial percentage of all hospitalizations. In 2011, CVD was responsible for 31% of all deaths, with ischemic heart disease (31%) and cerebrovascular diseases (30%) being the leading CVD causes. Despite an increase in the overall number of CVD deaths, the age-adjusted mortality rates for CVD declined 24% between 2000 and 2011. Health care delivered by Brazil's universal public health system, which focuses on primary prevention, has contributed to this achievement. However, the decline in age-adjusted mortality differs according to race, sex, and socioeconomic status with black individuals and lower-income populations sustaining the greatest impact of CVD, especially at younger ages. With one of the world's largest public health systems in terms of population coverage, Brazil has the means to implement actions to confront the high burden of CVD, focusing on health promotion and comprehensive care. Insufficient funding, low education levels, and social inequalities remain as the main barriers to be overcome.

234 citations

Journal ArticleDOI
TL;DR: In this article, a review of double resonance Raman spectroscopy is presented, where non-zone center phonon modes in solids can be observed in the double-resonance Raman spectrum, in which weak Raman signals appear in a wide frequency region and their combination or overtone modes can be assigned.
Abstract: A review of double resonance Raman spectroscopy is presented. Non-zone centre phonon modes in solids can be observed in the double resonance Raman spectra, in which weak Raman signals appear in a wide frequency region and their combination or overtone modes can be assigned. By changing the excitation laser energy, we can derive the phonon dispersion relations of a single nanotube.

234 citations

Journal ArticleDOI
TL;DR: The evidence showing a role for the genetic constitution of T. cruzi in determining the clinical characteristics of Chagas disease is reviewed, and a ;clonal-histotropic model' for the pathogenesis of this disease is proposed.

233 citations

Journal ArticleDOI
TL;DR: Os dados sugerem that a automedicacao no Brasil reflete as carencias e habitos da populacao, e consideravelmente influenciADA pela prescricao medica e tem a sua qualidade prejudicada pela baixa seletividade do mercado farmaceutico.
Abstract: INTRODUCAO: Os dados apresentados fazem parte de um estudo multicentrico sobre automedicacao na America Latina realizado pela Organizacao Mundial de Saude (OMS). Objetivou-se tracar um perfil da automedicacao atraves da analise da procura de medicamentos em farmacias sem prescricao medica ou aconselhamento do farmaceutico/balconista. MATERIAL E METODO: As especialidades farmaceuticas foram classificadas pelo codigo "Anatomical Therapeutical Classification" e analisadas sob quatro aspectos qualitativos: valor intrinseco, essencialidade (lista da OMS e Relacao Nacional de Medicamentos Essenciais (RENAME), combinacao em dose fixa e necessidade de prescricao medica. RESULTADOS: Foram solicitadas 5.332 especialidades farmaceuticas (785 diferentes principios ativos), sendo 49,5% combinacoes em dose fixas, 53,0% de valor intrinseco nao elevado, 44,1% sujeitos a prescricao medica, 71,0% nao essenciais e 40,0% baseados em prescricoes medicas anteriores. Os medicamentos mais solicitados foram analgesicos (17,3%), descongestionantes nasais (7,0%), antiinflamatorio/antireumatico e antiinfecciosos de uso sistemico, ambos com 5,6%. CONCLUSOES: Os dados sugerem que a automedicacao no Brasil reflete as carencias e habitos da populacao, e consideravelmente influenciada pela prescricao medica e tem a sua qualidade prejudicada pela baixa seletividade do mercado farmaceutico.

232 citations


Authors

Showing all 42077 results

NameH-indexPapersCitations
Michael Marmot1931147170338
Pulickel M. Ajayan1761223136241
Alan D. Lopez172863259291
Jens Nielsen1491752104005
Mildred S. Dresselhaus136762112525
Jing Kong12655372354
Mauricio Terrones11876061202
Michael Brammer11842446763
Terence G. Langdon117115861603
Caroline A. Sabin10869044233
Michael Brauer10648073664
Michael Bader10373537525
Michael S. Strano9848060141
Pablo Jarillo-Herrero9124539171
Riichiro Saito9150248869
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023111
2022624
20215,708
20205,955
20195,269
20185,020