Universidade Positivo

About: Universidade Positivo is a education organization based out in Curitiba, Brazil. It is known for research contribution in the topics: Population & Biodiversity. The organization has 1290 authors who have published 1237 publications receiving 9335 citations. The organization is also known as: Positive University.

Serological profile of John Cunningham virus (JCV) in patients with multiple sclerosis

Abstract: Treatment options for multiple sclerosis (MS) have changed over the last few years, bringing about a new category of drugs with more efficient profiles. However, these drugs have come with a whole new profile of potential adverse events that neurologists have to learn well and quickly. One of the most feared complications of these MS treatments is progressive multifocal leukoencephalopathy caused by the reactivation of the John Cunningham virus (JCV). Objective: To identify the serologic profile of JCV in patients with MS. Methods: Data on serum antibodies for JCV were obtained using the enzyme-linked immunosorbent assay provided by the STRATIFY-JCV program. Results: A total of 1,501 blood tests were obtained from 1,102 patients with MS. There were 633 patients (57.1%) who were positive for antibodies for JCV and 469 patients who were negative (42.9%). Twenty-three patients became positive after initially having negative JCV antibody status. The rate of seroconversion was 18.5% over 22 months. Conclusion: The JCV serologic profile and seroconversion in Brazilian patients were similar to those described in other countries.

A sintaxe espacial de curitiba

Abstract: O presente trabalho desenvolve algumas analises dos padroes espaciais mensuraveis e quantificaveis por meio dos instrumentos analiticos da sintaxe espacial. Serao discutidas questoes relativas a nocao de centro da cidade e a percepcao dos curitibanos do complexo urbano. O pressuposto fundamental da teoria da sintaxe espacial define que os padroes estabelecidos pela forma ou maneira como as massas construidas estao dispostas espacialmente ordenam a relacao entre as pessoas. Justifica-se a opcao metodologica porque, dentre as pesquisas realizadas sobre a cidade de Curitiba, nao ha indicacoes de representacao do espaco sob uma ordem topologica, destacando seus atributos: proximidade, continuidade, descontinuidade, contiguidade, segregacao e integracao.

Evaluation of nonadherence to treatment among patients with schizophrenia attending psychosocial care centers in the south region of Brazil.

Abstract: Introduction The treatment of schizophrenia aims to reduce symptoms, improve quality of life and promote recovery from debilitating effects. Nonadherence to treatment is related to several factors and may lead to persistence of symptoms and relapse. Worldwide, the rate of nonadherence to treatment in individuals with schizophrenia is around 50%. Objectives To compare the clinical profile of nonadherent and adherent patients among individuals diagnosed with schizophrenia receiving treatment at psychosocial care centers in a city in southern Brazil. Method The clinical-epidemiological profile of patients with schizophrenia was retrospectively analyzed based on medical records entered into the system between January and December 2016, evaluating data at one-year follow-up. Results 112 patients were included. The disease was more prevalent in men; mean age was 40.5 years, being lower among men. Most of the sample had a low level of education, was unemployed/retired, did not have children and resided with relatives. The highest rate of diagnosis was among young adults. Psychotic symptoms were most frequently described, and the most commonly prescribed antipsychotic was haloperidol. The nonadherence rate was 15.2%; only one patient required admission to a psychiatric hospital. Among nonadherent patients, the mean time of attendance was 6 months; there were more nonadherent women than men. The most prevalent age range of nonadherence was 41-64 years. Psychosocial and clinical data were similar across the whole sample. Conclusion A nonadherence rate of 15.2% was found among individuals receiving treatment for schizophrenia, suggesting that psychosocial care centers were effective in treating and monitoring these patients.

Anatomia de Rhipsalis subgênero Erythrorhipsalis A. Berger (Rhipsalideae, Cactaceae)

Abstract: The goal of the present study was the anatomical analysis of the species belonging to the subgenus Erythrorhipsalis aiming to identify diagnostic features and potential synapomorphies. Six out of the nine species were collected and processed for anatomical study. The species have uniseriate or multisseriate epidermis; parallelocytic stomata; collenchymatic hypodermis; chlorenchyma below hypodermis; mucilaginous cells, cortical bundles and druses are present in the cortex; the vascular cylinder is surrounded by a continuous layer of sclerenchyma external to the collapsed phloem; secondary phloem and xylem are present. Several features are informative for distinguishing species, with potential use in the group phylogeny. We highlight the shape of epidermal cells, the presence and arrangement of sclerenchyma in cortex and pith, the occurrence of mucilage secretory structures in the pith, and the disposition of unlignifi ed parenchyma in the secondary xylem.