Universidade São Judas Tadeu

About: Universidade São Judas Tadeu is a education organization based out in São Paulo, Brazil. It is known for research contribution in the topics: Aerobic exercise & Baroreflex. The organization has 736 authors who have published 852 publications receiving 4782 citations.

Atividades acadêmico-científico-culturais na formação do profissional de Educação Física

Abstract: Este estudo discute a importância da inclusao das atividades academico-cientifico-culturais (AACC) como estrategia para ampliar a formacao dos futuros profissionais de Educacao Fisica (EF) e descreve como vem sendo compreendidas e conduzidas nos cursos de Licenciatura e Bacharelado de sete Instituicoes de Ensino Superior de diferentes estados brasileiros que oferecem ambas modalidades de curso. Trata-se de um estudo qualitativo-descritivo que utiliza como fonte de dados os regulamentos publicados nos sites das Instituicoes que foram analisados segundo categorias tematicas pre-determinadas e discutidos a luz da fundamentacao teorica da legislacao educacional sobre a formacao universitaria no Brasil. Concluiu-se que as finalidades previstas na legislacao tem sido parcialmente alcancadas uma vez que sua implementacao nas Instituicoes estudadas denota apropriacao parcial e, algumas vezes, equivocada de seu conteudo, o que indica a necessidade de ajustes para que o graduando possa ter sua formacao cultural enriquecida com tais praticas.

Effect of mild aerobic training on the myocardium of mice with chronic Chagas disease.

Abstract: Background Chronic chagasic heart disease represents extensive remodeling of the cardiovascular system, manifested as cardiac denervation, interstitial mononuclear infiltrate, myocyte and vascular degenerative changes, fibrosis, and hypertrophy. Moreover, aerobic exercises are widely indicated for the treatment of various disorders of the cardiovascular system.

Advanced Glycated apoA-IV Loses Its Ability to Prevent the LPS-Induced Reduction in Cholesterol Efflux-Related Gene Expression in Macrophages

Abstract: We addressed how advanced glycation (AGE) affects the ability of apoA-IV to impair inflammation and restore the expression of genes involved in cholesterol efflux in lipopolysaccharide- (LPS-) treated macrophages. Recombinant human apoA-IV was nonenzymatically glycated by incubation with glycolaldehyde (GAD), incubated with cholesterol-loaded bone marrow-derived macrophages (BMDMs), and then stimulated with LPS prior to measurement of proinflammatory cytokines by ELISA. Genes involved in cholesterol efflux were quantified by RT-qPCR, and cholesterol efflux was measured by liquid scintillation counting. Carboxymethyllysine (CML) and pyrraline (PYR) levels, determined by Liquid Chromatography-Mass Spectrometry (LC-MS/MS), were greater in AGE-modified apoA-IV (AGE-apoA-IV) compared to unmodified-apoA-IV. AGE-apoA-IV inhibited expression of interleukin 6 (Il6), TNF-alpha (Tnf), IL-1 beta (Il1b), toll-like receptor 4 (Tlr4), tumor necrosis factor receptor-associated factor 6 (Traf6), Janus kinase 2/signal transducer and activator of transcription 3 (Jak2/Stat3), nuclear factor kappa B (Nfkb), and AGE receptor 1 (Ddost) as well as IL-6 and TNF-alpha secretion. AGE-apoA-IV alone did not change cholesterol efflux or ABCA-1 levels but was unable to restore the LPS-induced reduction in expression of Abca1 and Abcg1. AGE-apoA-IV inhibited inflammation but lost its ability to counteract the LPS-induced changes in expression of genes involved in macrophage cholesterol efflux that may contribute to atherosclerosis.

Conversão do conhecimento é fonte de Vantagem Competitiva Sustentável? uma análise empírica sob a perspectiva da Resource-based View

Abstract: Distincoes entre Vantagem Competitiva (VC) e Vantagem Competitiva Sustentavel (VCS), apresentadas por Wernerfelt (1984, 1995), Barney (1986a, 1986b, 1991) e Barney e Arikan (2001), indicam que a VCS tende a resistir as tentativas de duplicacao. Com o presente estudo, foi analisado se o modelo SECI de conversao do conhecimento (NONAKA; TAKEUCHI, 2004) e avaliado pelos gestores organizacionais como uma fonte de VCS, segundo a perspectiva da Resource-based View (RBV). Por meio de estudo de campo, mediante a aplicacao de um questionario estruturado fechado junto a 200 gestores, concluiu-se que a visao do gestor e divergente dos indicadores conceituais que qualificam o modelo SECI como vetor de Vantagem Competitiva Sustentavel na perspectiva da RBV. Em outras palavras, enquanto a literatura afirma que o modelo SECI e gerador VCS, no presente estudo identificou-se que a opiniao dos gestores nao converge para essa afirmacao, sugerindo que, na pratica, a teoria e outra.

Muscle hypertrophy and ladder-based resistance training for rodents: A systematic review and meta-analysis

Abstract: This study aimed to review the effects of ladder-based resistance training (LRT) on muscle hypertrophy and strength in rodents through a systematic review with meta-analysis. We systematically searched PubMed/Medline, SportDiscuss, Scopus, Google Scholar, Science Direct, and Scielo database on May 18, 2020. Thirty-four studies were included measuring total (mCSA) or mean muscle fibers cross-sectional area (fCSA) or maximum load-carrying capacity (MLCC) or muscle mass (MM). About the main results, LRT provides sufficient mechanical stimulation to increase mCSA and fCSA. Meta-analysis showed a significant overall effect on the fCSA (SMD 1.89, 95% CI [1.18, 2.61], p < .00001, I2 = 85%); however, subgroup analysis showed that some muscle types might not be hypertrophied through the LRT. Meta-analysis showed a significant training effect on the MM (SMD 0.92, 95% CI [0.52, 1.32], p < .00001, I2 = 72%). Sub-group analysis revealed that soleus (SMD 1.32, 95% CI [0.11, 2.54], p = .03, I2 = 86%) and FHL (SMD 1.92, 95% CI [1.00, 2.85], p < .0001, I2 = 71%) presented significant training effects, despite moderate heterogeneity levels (I2 = 72%). MLCC increases considerably after a period of LRT, regardless of its duration and the characteristics of the protocols (SMD 12.37, 95% CI [9.36, 15.37], p < .00001, I2 = 90%). Through these results, we reach the following conclusions: (a) LRT is efficient to induce muscle hypertrophy, although this effect varies between different types of skeletal muscles, and; (b) the ability of rodents to carry load increases regardless of the type and duration of the protocol used.