Institution
Université catholique de Louvain
Education•Louvain-la-Neuve, Belgium•
About: Université catholique de Louvain is a education organization based out in Louvain-la-Neuve, Belgium. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 25319 authors who have published 57360 publications receiving 2172080 citations. The organization is also known as: University of Louvain & UCLouvain.
Papers published on a yearly basis
Papers
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TL;DR: The DOPPS provides a useful comparison benchmark for the state of mineral metabolism management of patients with kidney disease and affirms the association between mineral metabolism and important patient outcomes.
318 citations
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TL;DR: In this paper, a general framework for the formulation and analysis of rigid no-slip boundary conditions for numerical schemes for the solution of the incompressible Navier-Stokes equations is presented.
Abstract: A general framework is presented for the formulation and analysis of rigid no-slip boundary conditions for numerical schemes for the solution of the incompressible Navier-Stokes equations. It is shown that fractional-step (splitting) methods are prone to introduce a spurious numerical boundary layer that induces substantial time differencing errors. High-order extrapolation methods are analyzed to reduce these errors. Both improved pressure boundary condition and velocity boundary condition methods are developed that allow accurate implementation of rigid no-slip boundary conditions.
318 citations
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Budapest University of Technology and Economics1, ETH Zurich2, Bristol-Myers Squibb3, University College Dublin4, University of Applied Sciences and Arts Northwestern Switzerland FHNW5, Delft University of Technology6, GlaxoSmithKline7, Hunan University8, Newcastle University9, Siemens10, Lappeenranta University of Technology11, Hoffmann-La Roche12, Åbo Akademi University13, University of Helsinki14, Martin Luther University of Halle-Wittenberg15, Massachusetts Institute of Technology16, Université catholique de Louvain17, Nova Southeastern University18, National University of Singapore19, Food and Drug Administration20, FMC Technologies21, University of Tulsa22, Purdue University23
TL;DR: In this paper, a multiauthor review article aims to bring readers up to date with some of the current trends in the field of process analytical technology (PAT) by summarizing each aspect of the subject (sensor development, PAT based process monitoring and control methods) and presenting applications both in industrial laboratories and in manufacture.
318 citations
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TL;DR: Candidate health-promoting effector molecules of lactobacilli can then be validated via mutant approaches, which will allow for improved strain selection procedures, improved product quality control criteria and molecular science-based health claims.
Abstract: Lactobacilli belong to the lactic acid bacteria, which play a key role in industrial and artisan food raw-material fermentation, including a large variety of fermented dairy products. Next to their role in fermentation processes, specific strains of Lactobacillus are currently marketed as health-promoting cultures or probiotics. The last decade has witnessed the completion of a large number of Lactobacillus genome sequences, including the genome sequences of some of the probiotic species and strains. This development opens avenues to unravel the Lactobacillus-associated health-promoting activity at the molecular level. It is generally considered likely that an important part of the Lactobacillus effector molecules that participate in the proposed health-promoting interactions with the host (intestinal) system resides in the bacterial cell envelope. For this reason, it is important to accurately predict the Lactobacillus exoproteomes. Extensive annotation of these exoproteomes, combined with comparative analysis of species- or strain-specific exoproteomes, may identify candidate effector molecules, which may support specific effects on host physiology associated with particular Lactobacillus strains. Candidate health-promoting effector molecules of lactobacilli can then be validated via mutant approaches, which will allow for improved strain selection procedures, improved product quality control criteria and molecular science-based health claims.
318 citations
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TL;DR: New findings that may explain how gut microbiota can be involved in the control of energy and metabolic homeostasis are discussed and gut microflora may play an even more important role in maintaining human health than previously thought.
Abstract: PURPOSE OF REVIEW: Gut microbiota plays an important role in health and disease, but this ecosystem remains incompletely characterized and shows a wide diversity. This review discusses new findings that may explain how gut microbiota can be involved in the control of energy and metabolic homeostasis. RECENT FINDINGS: Over the past 5 years studies have highlighted some key aspects of the mammalian host-gut microbial relationship. Gut microbiota could now be considered a 'microbial organ' placed within a host organ. Recent data suggest that the modulation of gut microbiota affects host metabolism and has an impact on energy storage. Several mechanisms are proposed that link events occurring in the colon and the regulation of energy metabolism. SUMMARY: Gut microflora may play an even more important role in maintaining human health than previously thought. The literature provides new evidence that the increased prevalence of obesity and type 2 diabetes cannot be attributed solely to changes in the human genome, nutritional habits, or reduction of physical activity in our daily lives. One must also consider this important new environmental factor, namely gut microbiota. Scientists may take into consideration a key question: could we manipulate the microbiotic environment to treat or prevent obesity and type 2 diabetes? This opens up a new area in nutrition research.
318 citations
Authors
Showing all 25540 results
Name | H-index | Papers | Citations |
---|---|---|---|
Robert Langer | 281 | 2324 | 326306 |
Pulickel M. Ajayan | 176 | 1223 | 136241 |
Klaus Müllen | 164 | 2125 | 140748 |
Giacomo Bruno | 158 | 1687 | 124368 |
Willem M. de Vos | 148 | 670 | 88146 |
David Goldstein | 141 | 1301 | 101955 |
Krzysztof Piotrzkowski | 141 | 1269 | 99607 |
Andrea Giammanco | 135 | 1362 | 98093 |
Christophe Delaere | 135 | 1320 | 96742 |
Vincent Lemaitre | 134 | 1310 | 99190 |
Michael Tytgat | 134 | 1449 | 94133 |
Jian Li | 133 | 2863 | 87131 |
Jost B. Jonas | 132 | 1158 | 166510 |
George Stephans | 132 | 1337 | 86865 |
Peter Hall | 132 | 1640 | 85019 |