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Institution

Université de Sherbrooke

EducationSherbrooke, Quebec, Canada
About: Université de Sherbrooke is a education organization based out in Sherbrooke, Quebec, Canada. It is known for research contribution in the topics: Population & Receptor. The organization has 14922 authors who have published 28783 publications receiving 792511 citations. The organization is also known as: Universite de Sherbrooke & Sherbrooke University.


Papers
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Journal ArticleDOI
09 Apr 2004-AIDS
TL;DR: In Accra, approximately four-fifths of prevalent cases of HIV in adult males were acquired from SW, and comprehensive interventions providing education, condoms and treatment for sexually transmitted diseases for SW and their clients should be approached as other public health priorities.
Abstract: OBJECTIVE: To delineate the population attributable fraction (PAF) of transactional sex in prevalent cases of HIV infection in the male adult population of Accra, Ghana. DESIGN AND METHODS: Cross-sectional study of clients who visited a sex worker (SW), of boyfriends of SW and of male personnel in prostitution venues. A questionnaire was administered and urine obtained for detection of anti-HIV antibodies. The PAF of prevalent HIV acquired from SW was calculated using a combination of data from this survey of clients, from on-going SW surveys, the national HIV surveillance system and the national census. RESULTS: HIV prevalence was 4.9% (8/162) among clients of mobile SW, 15.8% (53/335) among clients of home-based SW, 17.5% (10/57) among personnel and 32.1% (9/28) among boyfriends. A condom was used in 90% of intercourses, according to clients. Non-use of a condom was clustered in selected locations and independently associated with older age of client, frequency of intercourse with SW in the last year and current urethritis. Among the male population of Accra aged 15-59 years, 84% of prevalent cases of HIV were attributable to transactional sex. A sensitivity analysis showed that under various assumptions PAF varied between 47% and 100%. CONCLUSIONS: In Accra, approximately four-fifths of prevalent cases of HIV in adult males were acquired from SW. Comprehensive interventions providing education, condoms and treatment for sexually transmitted diseases for SW and their clients should be approached as other public health priorities and provided in all cities, large and small, of West Africa.

200 citations

Journal ArticleDOI
TL;DR: It is found that in the presence of a 62.5 THz field, a single circularly polarized 114 as pulse can be generated by an elliptical polarized laser pulse at a wavelength of 400 nm with an ellipticity of ϵ=0.59.
Abstract: We present a method for producing a single circularly polarized attosecond pulse by an intense few cycle elliptically polarized laser pulse combined with a terahertz field from numerical solutions of the time-dependent Schr\"odinger equation for the molecular ion ${\mathrm{H}}_{2}^{+}$. It is found that in the presence of a 62.5 THz ($\ensuremath{\lambda}=4800\text{ }\text{ }\mathrm{nm}$) field at an intensity of $\ensuremath{\sim}{10}^{14}\text{ }\text{ }\mathrm{W}/{\mathrm{cm}}^{2}$, a single circularly polarized 114 as pulse can be generated by an elliptical polarized laser pulse at a wavelength of 400 nm with an ellipticity of $ϵ=0.59$. The efficiency of circular polarization attosecond pulse generation is interpreted based on a classical model of single electron recollision with the parent ion.

200 citations

Journal ArticleDOI
TL;DR: The recently available information on the formation and processing of several classes of complex DNA damage formed upon one radical hit including mostly hydroxyl radical and one-electron oxidants is critically reviewed.

200 citations

Journal ArticleDOI
TL;DR: Immunosuppressed patients without AIDS had longer time to treatment and a higher rate of death than did patients with AIDS.
Abstract: Pneumocystis jirovecii pneumonia (PCP) in patients without AIDS is increasingly common. We conducted a prospective cohort study of consecutive patients with proven PCP; of 544 patients, 223 (41%) had AIDS (AIDS patients) and 321 (59%) had other immunosuppressive disorders (non-AIDS patients). Fewer AIDS than non-AIDS patients required intensive care or ventilation, and the rate of hospital deaths—17.4% overall—was significantly lower for AIDS versus non-AIDS patients (4% vs. 27%; p<0.0001). Multivariable analysis showed the odds of hospital death increased with older age, receipt of allogeneic bone marrow transplant, immediate use of oxygen, need for mechanical ventilation, and longer time to treatment; HIV-positive status or receipt of a solid organ transplant decreased odds for death. PCP is more often fatal in non-AIDS patients, but time to diagnosis affects survival and is longer for non-AIDS patients. Clinicians must maintain a high index of suspicion for PCP in immunocompromised patients who do not have AIDS.

200 citations

Journal ArticleDOI
TL;DR: A critical review of both experimental and computational studies of round turbulent jets is provided, beginning with the work of Tollmien (1926). as discussed by the authors traces the history, major advances, and various stages that the research community went through over the past 85-odd years, from statistical analyses through to the use of conditional sampling, proper orthogonal decomposition and structural eduction methods.

200 citations


Authors

Showing all 15051 results

NameH-indexPapersCitations
Masashi Yanagisawa13052483631
Joseph V. Bonventre12659661009
Jeffrey L. Benovic9926430041
Alessio Fasano9647834580
Graham Pawelec8957227373
Simon C. Robson8855229808
Paul B. Corkum8857637200
Mario Leclerc8837435961
Stephen M. Collins8632025646
Ed Harlow8619061008
William D. Fraser8582730155
Jean Cadet8337224000
Vincent Giguère8222727481
Robert Gurny8139628391
Jean-Michel Gaillard8141026780
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202384
2022189
20211,858
20201,805
20191,625
20181,543