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Institution

Université de Sherbrooke

EducationSherbrooke, Quebec, Canada
About: Université de Sherbrooke is a education organization based out in Sherbrooke, Quebec, Canada. It is known for research contribution in the topics: Population & Receptor. The organization has 14922 authors who have published 28783 publications receiving 792511 citations. The organization is also known as: Universite de Sherbrooke & Sherbrooke University.


Papers
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Journal ArticleDOI
TL;DR: In this paper, a new stereoelectronic theory for the cleavage of the tetrahedral intermediate in the hydrolysis of esters and amides is presented, based on the orientation of the lone pair orbitals of the hetero-atoms.

197 citations

Journal ArticleDOI
TL;DR: In this paper, the relationship between microwave photons has been measured using a series of amplifiers and digital analysis, and the relationship has been shown to be robust to radiation at this wavelength.
Abstract: Detecting and counting individual microwave photons is important for processing quantum information, but it is made challenging by an absence of detectors that are sensitive enough to radiation at this wavelength Correlations between microwave photons have now been measured using a series of amplifiers and digital analysis

197 citations

Journal ArticleDOI
TL;DR: La revue donne aussi des exemples de lutte biologique contre les agents phytopathogenes bacteriens and fongiques par l’utilisation d’especes d‘actinomycetes deja disponibles sur le marche ou qui le seront probablement au cours des prochaines annees.
Abstract: Les actinomycetes representent une grande proportion de la biomasse microbienne du sol et ont la capacite de produire une large variete d’antibiotiques et d’enzymes extracellulaires. Plusieurs souches d’actinomycetes s’averent capables de proteger les plantes contre des maladies. Cette revue se penche sur le potentiel des actinomycetes comme (a) source de composes agronomiques, (b) agents stimulant la croissance des plantes et (c) agents de lutte biologique. La revue donne aussi des exemples de lutte biologique contre les agents phytopathogenes bacteriens et fongiques par l’utilisation d’especes d’actinomycetes deja disponibles sur le marche ou qui le seront probablement au cours des prochaines annees.

197 citations

Journal ArticleDOI
TL;DR: It is demonstrated that end of gestation exposure of pregnant rats to systemic microbial product (LPS) triggers placental inflammation and massive cell death, fetal mortality, and both forebrain white matter and motor behavioral alterations in the offspring, suggesting a possible protective treatment against human placental and fetal brain damage.
Abstract: The precise role of maternal bacterial infection and inflammation occurring at the end of gestation is a controversial matter. Although it is recognized as an independent risk factor for neurodevelopmental diseases such as cerebral palsy, mental deficiency, and autism, it remains unclear whether it is causal or simply associated with the diseases. In this study, we demonstrate that IL-1 plays a key role in mediating severe placental damage and neurodevelopmental anomalies in offspring. Our results show that end of gestation exposure of pregnant rats to systemic microbial product (LPS) triggers placental inflammation and massive cell death, fetal mortality, and both forebrain white matter and motor behavioral alterations in the offspring. All these effects are alleviated by the coadministration of IL-1 receptor antagonist with LPS, suggesting a possible protective treatment against human placental and fetal brain damage.

196 citations


Authors

Showing all 15051 results

NameH-indexPapersCitations
Masashi Yanagisawa13052483631
Joseph V. Bonventre12659661009
Jeffrey L. Benovic9926430041
Alessio Fasano9647834580
Graham Pawelec8957227373
Simon C. Robson8855229808
Paul B. Corkum8857637200
Mario Leclerc8837435961
Stephen M. Collins8632025646
Ed Harlow8619061008
William D. Fraser8582730155
Jean Cadet8337224000
Vincent Giguère8222727481
Robert Gurny8139628391
Jean-Michel Gaillard8141026780
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202384
2022189
20211,858
20201,805
20191,625
20181,543