Institution
Université de Sherbrooke
Education•Sherbrooke, Quebec, Canada•
About: Université de Sherbrooke is a education organization based out in Sherbrooke, Quebec, Canada. It is known for research contribution in the topics: Population & Receptor. The organization has 14922 authors who have published 28783 publications receiving 792511 citations. The organization is also known as: Universite de Sherbrooke & Sherbrooke University.
Papers published on a yearly basis
Papers
More filters
••
Peking Union Medical College1, Population Health Research Institute2, Simon Fraser University3, King Saud University4, Laval University5, The Chinese University of Hong Kong6, Sahlgrenska University Hospital7, Post Graduate Institute of Medical Education and Research8, Université de Sherbrooke9, UCSI University10, Dubai Health Authority11, Amrita Vishwa Vidyapeetham12, University of La Frontera13, University of the Philippines Manila14, North-West University15, Queen's University16, University of the Western Cape17, Independence University18, University of Wrocław19, Isfahan University of Medical Sciences20, Northwestern University21
TL;DR: Estimated total sleep duration of 6-8 h per day is associated with the lowest risk of deaths and major cardiovascular events and daytime napping isassociated with increased risks of major cardiovascular Events but not in those sleeping ≤6’h/night.
Abstract: Aims To investigate the association of estimated total daily sleep duration and daytime nap duration with deaths and major cardiovascular events. Methods and results We estimated the durations of total daily sleep and daytime naps based on the amount of time in bed and self-reported napping time and examined the associations between them and the composite outcome of deaths and major cardiovascular events in 116 632 participants from seven regions. After a median follow-up of 7.8 years, we recorded 4381 deaths and 4365 major cardiovascular events. It showed both shorter (≤6 h/day) and longer (>8 h/day) estimated total sleep durations were associated with an increased risk of the composite outcome when adjusted for age and sex. After adjustment for demographic characteristics, lifestyle behaviours and health status, a J-shaped association was observed. Compared with sleeping 6-8 h/day, those who slept ≤6 h/day had a non-significant trend for increased risk of the composite outcome [hazard ratio (HR), 1.09; 95% confidence interval, 0.99-1.20]. As estimated sleep duration increased, we also noticed a significant trend for a greater risk of the composite outcome [HR of 1.05 (0.99-1.12), 1.17 (1.09-1.25), and 1.41 (1.30-1.53) for 8-9 h/day, 9-10 h/day, and >10 h/day, Ptrend Conclusion Estimated total sleep duration of 6-8 h per day is associated with the lowest risk of deaths and major cardiovascular events. Daytime napping is associated with increased risks of major cardiovascular events and deaths in those with >6 h of nighttime sleep but not in those sleeping ≤6 h/night.
166 citations
••
Norwegian University of Science and Technology1, University of Cape Town2, University of Kansas3, University of California, Los Angeles4, Auburn University5, Université de Sherbrooke6, Claude Bernard University Lyon 17, Mauritian Wildlife Foundation8, Durrell Wildlife Conservation Trust9, University of Reading10
TL;DR: Based on long-term studies of growing populations of birds and mammals, population dynamics is analyzed by using fluctuations in the total reproductive value of the population to account for random fluctuations in age distribution.
Abstract: A major question in ecology is how age-specific variation in demographic parameters influences population dynamics. Based on long-term studies of growing populations of birds and mammals, we analyze population dynamics by using fluctuations in the total reproductive value of the population. This enables us to account for random fluctuations in age distribution. The influence of demographic and environmental stochasticity on the population dynamics of a species decreased with generation time. Variation in age-specific contributions to total reproductive value and to stochastic components of population dynamics was correlated with the position of the species along the slow-fast continuum of life-history variation. Younger age classes relative to the generation time accounted for larger contributions to the total reproductive value and to demographic stochasticity in "slow" than in "fast" species, in which many age classes contributed more equally. In contrast, fluctuations in population growth rate attributable to stochastic environmental variation involved a larger proportion of all age classes independent of life history. Thus, changes in population growth rates can be surprisingly well explained by basic species-specific life-history characteristics.
166 citations
••
TL;DR: Based on meta-analysis, split-dose regimens increase the quality of colon cleansing and are preferred by patients compared with day-before preparations, and additional research is required to evaluate oral sulfate solution-based and PEG low-volume regimens further.
166 citations
••
TL;DR: This review highlights recent progress in understanding of how the altered splicing function of RNA-binding proteins contributes to myelodysplastic syndromes, cancer, and neuropathologies.
Abstract: Examples of associations between human disease and defects in pre–messenger RNA splicing/alternative splicing are accumulating. Although many alterations are caused by mutations in splicing signals or regulatory sequence elements, recent studies have noted the disruptive impact of mutated generic spliceosome components and splicing regulatory proteins. This review highlights recent progress in our understanding of how the altered splicing function of RNA-binding proteins contributes to myelodysplastic syndromes, cancer, and neuropathologies.
166 citations
••
TL;DR: In this article, a semi-empirical calibration of the Integral Equation Model (IEM) backscattering model was proposed to better reproduce the radar backscatter coefficient over bare agricultural soils.
Abstract: Estimating surface parameters by radar-image inversion requires the use of well-calibrated backscattering models. None of the existing models is capable of correctly simulating scatterometer or satellite radar data. We propose a semi-empirical calibration of the Integral Equation Model (IEM) backscattering model in order to better reproduce the radar backscattering coefficient over bare agricultural soils. As correlation length is not only the least accurate but also the most difficult to measure of the parameters required in the models, we propose that it be replaced by a calibration parameter that would be estimated empirically from experimental databases of radar images and field measurements. This calibration was carried out using a number of radar configurations with different incidence angles, polarization configurations, and radar frequencies. Using several databases, the relationship between the calibration parameter and the surface roughness was determined for each radar configuration. In additio...
166 citations
Authors
Showing all 15051 results
Name | H-index | Papers | Citations |
---|---|---|---|
Masashi Yanagisawa | 130 | 524 | 83631 |
Joseph V. Bonventre | 126 | 596 | 61009 |
Jeffrey L. Benovic | 99 | 264 | 30041 |
Alessio Fasano | 96 | 478 | 34580 |
Graham Pawelec | 89 | 572 | 27373 |
Simon C. Robson | 88 | 552 | 29808 |
Paul B. Corkum | 88 | 576 | 37200 |
Mario Leclerc | 88 | 374 | 35961 |
Stephen M. Collins | 86 | 320 | 25646 |
Ed Harlow | 86 | 190 | 61008 |
William D. Fraser | 85 | 827 | 30155 |
Jean Cadet | 83 | 372 | 24000 |
Vincent Giguère | 82 | 227 | 27481 |
Robert Gurny | 81 | 396 | 28391 |
Jean-Michel Gaillard | 81 | 410 | 26780 |