Institution
Université de Sherbrooke
Education•Sherbrooke, Quebec, Canada•
About: Université de Sherbrooke is a education organization based out in Sherbrooke, Quebec, Canada. It is known for research contribution in the topics: Population & Receptor. The organization has 14922 authors who have published 28783 publications receiving 792511 citations. The organization is also known as: Universite de Sherbrooke & Sherbrooke University.
Topics: Population, Receptor, Health care, Angiotensin II, Poison control
Papers published on a yearly basis
Papers
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TL;DR: Using cluster perturbation theory, it is shown that the spectral weight and pseudogap observed at the Fermi energy in recent angle resolved photoemission spectroscopy of both electron- and hole-doped high-temperature superconductors find their natural explanation within the t-t(')-t(")-U Hubbard model in two dimensions.
Abstract: Using cluster perturbation theory, it is shown that the spectral weight and pseudogap observed at the Fermi energy in recent angle resolved photoemission spectroscopy of both electron- and hole-doped high-temperature superconductors find their natural explanation within the $t\mathrm{\text{\ensuremath{-}}}{t}^{\ensuremath{'}}\mathrm{\text{\ensuremath{-}}}{t}^{\ensuremath{'}\ensuremath{'}}\mathrm{\text{\ensuremath{-}}}U$ Hubbard model in two dimensions. The value of the interaction $U$ needed to explain the experiments for electron-doped systems at optimal doping is in the weak to intermediate coupling regime where the $t\mathrm{\text{\ensuremath{-}}}J$ model is inappropriate. At strong coupling, short-range correlations suffice to create a pseudogap, but at weak-coupling long correlation lengths associated with the antiferromagnetic wave vector are necessary.
162 citations
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TL;DR: DNA damage by low-energy electrons (LEE) was examined using a novel system in which thin solid films of oligonucleotide tetramers were irradiated with monoenergetic electrons under ultrahigh vacuum and the distribution of nonmodified products suggests a mechanism of damage involving initial electron attachment to nucleobase moieties, followed by electron transfer to the sugar-phosphate backbone, and subsequent dissociation of the phosphodiester bond.
Abstract: DNA damage by low-energy electrons (LEE) was examined using a novel system in which thin solid films of oligonucleotide tetramers (CGTA and GCAT) were irradiated with monoenergetic electrons (10 eV) under ultrahigh vacuum. The products of irradiation were examined by HPLC. These analyses permitted the quantitation of 16 nonmodified nucleobase, nucleoside, and nucleotide fragments of each tetramer resulting from the cleavage of phosphodiester and N-glycosidic bonds. The distribution of nonmodified products suggests a mechanism of damage involving initial electron attachment to nucleobase moieties, followed by electron transfer to the sugar−phosphate backbone, and subsequent dissociation of the phosphodiester bond. Moreover, virtually all the nonmodified fragments contained a terminal phosphate group at the site of cleavage. These results demonstrate that the phosphodiester bond breaks by a distinct pathway in which the negative charge localizes on the phosphodiester bond giving rise to nonmodified fragment...
162 citations
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University of Regensburg1, Leiden University Medical Center2, Innsbruck Medical University3, Erasmus University Rotterdam4, GlaxoSmithKline5, Université de Sherbrooke6, University of Bristol7, King's College London8, McGill University9, National Institutes of Health10, Boston University11, Broad Institute12, Harvard University13, Wellcome Trust Sanger Institute14, University of Cambridge15, University Hospital of Lausanne16, University of Lübeck17
TL;DR: It is demonstrated that the ADIPOQ gene is the only major gene for plasma adiponectin, which explains 6.7% of the phenotypic variance, and that neither this gene nor any of the metabolic syndrome loci explained the sex differences observed in men and women.
162 citations
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TL;DR: Prescription opioid injectors who do not inject heroin are at greater risk for HCV seroconversion than are those injecting both heroin and prescription opioids.
Abstract: Ce manuscrit est une pre-publication d'un article paru dans Addiction 2012; 107(7): 1318-1327 url: http://www.addictionjournal.org/
162 citations
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TL;DR: It is argued that their high mass-specific milk production forces lactating females to nurse at night, which in turn imposes a constraint on foraging distances, and so the shift to a smaller home range is probably facilitated by the concomitant increase in insect biomass during the July lactation period.
Abstract: As income breeders, lactating female bats rely on current resource intake to support costs of reproduction and so must reconcile the conflicting demands of foraging and nursing. We documented changes in the movement of female little brown bats (Myotis lucifugus) around roosts between pregnancy and lactation. Home-range size dropped by 51% between pregnancy and lactation, resulting in a 35% decrease in flight distances. Although pregnant females rarely returned to roosts during the night, lactating females returned 1–2 times, which led to an increase in activity at the roosts beginning about 3 h after initial emergence. We argue that their high mass-specific milk production forces lactating females to nurse at night, which in turn imposes a constraint on foraging distances. The shift to a smaller home range is probably facilitated by the concomitant increase in insect biomass during the July lactation period.
162 citations
Authors
Showing all 15051 results
Name | H-index | Papers | Citations |
---|---|---|---|
Masashi Yanagisawa | 130 | 524 | 83631 |
Joseph V. Bonventre | 126 | 596 | 61009 |
Jeffrey L. Benovic | 99 | 264 | 30041 |
Alessio Fasano | 96 | 478 | 34580 |
Graham Pawelec | 89 | 572 | 27373 |
Simon C. Robson | 88 | 552 | 29808 |
Paul B. Corkum | 88 | 576 | 37200 |
Mario Leclerc | 88 | 374 | 35961 |
Stephen M. Collins | 86 | 320 | 25646 |
Ed Harlow | 86 | 190 | 61008 |
William D. Fraser | 85 | 827 | 30155 |
Jean Cadet | 83 | 372 | 24000 |
Vincent Giguère | 82 | 227 | 27481 |
Robert Gurny | 81 | 396 | 28391 |
Jean-Michel Gaillard | 81 | 410 | 26780 |