Institution
Université de Sherbrooke
Education•Sherbrooke, Quebec, Canada•
About: Université de Sherbrooke is a education organization based out in Sherbrooke, Quebec, Canada. It is known for research contribution in the topics: Population & Receptor. The organization has 14922 authors who have published 28783 publications receiving 792511 citations. The organization is also known as: Universite de Sherbrooke & Sherbrooke University.
Topics: Population, Receptor, Health care, Angiotensin II, Poison control
Papers published on a yearly basis
Papers
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TL;DR: In this article, the authors reviewed recent fundamental and applied studies of large herbivores with particular emphasis on the relationship between the spatial and temporal scales of ecosystem response, management decision and implementation.
Abstract: Summary 1. Wild large herbivores provide goods and income to rural communities, have major impacts on land use and habitats of conservation importance and, in some cases, face local or global extinction. As a result, substantial effort is applied to their management across the globe. To be effective, however, management has to be science-based. We reviewed recent fundamental and applied studies of large herbivores with particular emphasis on the relationship between the spatial and temporal scales of ecosystem response, management decision and implementation. 2. Long-term population dynamics research has revealed fundamental differences in how sex/age classes are affected by changes in density and weather. Consequently, management must be tailored to the age and sex structure of the population, rather than to simple population counts. 3. Herbivory by large ungulates shapes the structure, diversity and functioning of most terrestrial ecosystems. Recent research has shown that fundamental herbivore/vegetation interactions driving landscape change are localized, often at scales of a few metres. For example, sheep and deer will selectively browse heather Calluna vulgaris at the edge of preferred grass patches in heather moorland. As heather is vulnerable to heavy defoliation, in the long term this can lead to loss of heather cover despite the average utilization rate of heather in a management area being low. Therefore, while herbivore population management requires a large-scale approach, management of herbivore impacts on vegetation may require a much more flexible and site-specific approach. 4. Localized impacts on vegetation have cascading effects on biodiversity, because changes in vegetation structure and composition, induced by large herbivores affect habitat suitability for many other species. As such, grazing should be considered as a tool for broader biodiversity management requiring a more sophisticated approach than just, for example, eliminating grazing from conservation areas through the use of exclosures. 5. Synthesis and applications . The management of wild large herbivores must consider different spatial scales, from small patches of vegetation to boundaries of an animal population. It also requires long-term planning based on a deep understanding of how population processes, such a birth rate, death rate and age structure, are affected by changes in land use and climate and how these affect localized herbivore impacts. Because wild herbivores do not observe administrative or political boundaries, adjusting their management to socio-political realities can present a challenge. Many developing countries have established co-operative management groups that allow all interested parties to be involved in the development of management plans; developed countries have a lot to learn from the developing world’s example.
415 citations
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TL;DR: Upon UV light irradiation of polymer micellar solutions, the photosolvolysis of pyrene moieties results in their detachment from the polymer and converts the hydrophobic PPy block into hydrophilic poly(methacrylic acid).
Abstract: A new and general design strategy is presented for amphiphilic block copolymers whose micellar aggregates can be dissociated by light. A diblock copolymer composed of hydrophilic poly(ethylene oxide) (PEO) and a hydrophobic polymethacrylate bearing pyrene pendant groups (PPy) was synthesized using ATRP. Upon UV light irradiation of polymer micellar solutions, the photosolvolysis of pyrene moieties results in their detachment from the polymer and converts the hydrophobic PPy block into hydrophilic poly(methacrylic acid). This effect leads to complete dissociation of polymer micelles.
415 citations
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University of Calgary1, McGill University Health Centre2, Université du Québec à Trois-Rivières3, University of British Columbia4, Université de Montréal5, Laval University6, University of Alberta7, University of Toronto8, Ottawa Hospital Research Institute9, Hôpital Maisonneuve-Rosemont10, Memorial University of Newfoundland11, Centre for Addiction and Mental Health12, University of Ottawa13, McGill University14, University Health Network15, University of Western Ontario16, University of Saskatchewan17, University of Manitoba18, Concordia University Wisconsin19, Montreal General Hospital20, Heart and Stroke Foundation of Canada21, Dalhousie University22, Libin Cardiovascular Institute of Alberta23, Université de Sherbrooke24, McMaster University25, Université du Québec à Montréal26, Montreal Heart Institute27, Canadian Stroke Network28, Department of National Defence29, Simon Fraser University30, St George's, University of London31, Centre Hospitalier Universitaire Sainte-Justine32, Children's Hospital of Eastern Ontario33
TL;DR: In the diagnosis and assessment of hypertension, automated office blood pressure, taken without patient-health provider interaction, is now recommended as the preferred method of measuring in-office blood pressure as mentioned in this paper.
413 citations
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TL;DR: This work demonstrates a novel strategy enabling the use of a continuous-wave diode near-infrared (NIR) laser to disrupt block copolymer micelles and trigger the release of their "payloads", and uses UCNPs as an internal UV or visible light source upon NIR light excitation.
Abstract: We demonstrate a novel strategy enabling the use of a continuous-wave diode near-infrared (NIR) laser to disrupt block copolymer (BCP) micelles and trigger the release of their “payloads”. By encapsulating NaYF4:TmYb upconverting nanoparticles (UCNPs) inside micelles of poly(ethylene oxide)-block-poly(4,5-dimethoxy-2-nitrobenzyl methacrylate) and exposing the micellar solution to 980 nm light, photons in the UV region are emitted by the UCNPs, which in turn are absorbed by o-nitrobenzyl groups on the micelle core-forming block, activating the photocleavage reaction and leading to the dissociation of BCP micelles and release of co-loaded hydrophobic species. Our strategy of using UCNPs as an internal UV or visible light source upon NIR light excitation represents a general and efficient method to circumvent the need for UV or visible light excitation that is a common drawback for light-responsive polymeric systems developed for potential biomedical applications.
413 citations
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TL;DR: The lack of a comprehensive, validated, and easily accessible data base for the durability of fiber-reinforced polymer (FRP) composites as related to civil infrastructure applications has been identified as a critical barrier to widespread acceptance of these materials by structural designers and civil engineers as discussed by the authors.
Abstract: The lack of a comprehensive, validated, and easily accessible data base for the durability of fiber-reinforced polymer (FRP) composites as related to civil infrastructure applications has been identified as a critical barrier to widespread acceptance of these materials by structural designers and civil engineers. This concern is emphasized since the structures of interest are primarily load bearing and are expected to remain in service over extended periods of time without significant inspection or maintenance. This paper presents a synopsis of a gap analysis study undertaken under the aegis of the Civil Engineering Research Foundation and the Federal Highway Administration to identify and prioritize critical gaps in durability data. The study focuses on the use of FRP in internal reinforcement, external strengthening, seismic retrofit, bridge decks, structural profiles, and panels. Environments of interest are moisture/solution, alkalinity, creep/relaxation, fatigue, fire, thermal effects (including free...
411 citations
Authors
Showing all 15051 results
Name | H-index | Papers | Citations |
---|---|---|---|
Masashi Yanagisawa | 130 | 524 | 83631 |
Joseph V. Bonventre | 126 | 596 | 61009 |
Jeffrey L. Benovic | 99 | 264 | 30041 |
Alessio Fasano | 96 | 478 | 34580 |
Graham Pawelec | 89 | 572 | 27373 |
Simon C. Robson | 88 | 552 | 29808 |
Paul B. Corkum | 88 | 576 | 37200 |
Mario Leclerc | 88 | 374 | 35961 |
Stephen M. Collins | 86 | 320 | 25646 |
Ed Harlow | 86 | 190 | 61008 |
William D. Fraser | 85 | 827 | 30155 |
Jean Cadet | 83 | 372 | 24000 |
Vincent Giguère | 82 | 227 | 27481 |
Robert Gurny | 81 | 396 | 28391 |
Jean-Michel Gaillard | 81 | 410 | 26780 |