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Showing papers by "Université du Québec à Montréal published in 2013"


Journal ArticleDOI
12 Dec 2013-Nature
TL;DR: Sugimoto et al. as mentioned in this paper presented a bibliometric analysis confirming that gender imbalances persist in research output worldwide, and they concluded that gender imbalance persists in all fields.
Abstract: Cassidy R. Sugimoto and colleagues present a bibliometric analysis confirming that gender imbalances persist in research output worldwide.

972 citations


Journal ArticleDOI
28 May 2013-PLOS ONE
TL;DR: Comparisons between citations and metric values for articles published at different times, even within the same year, can remove or reverse this association and so publishers and scientometricians should consider the effect of time when using altmetrics to rank articles.
Abstract: Altmetric measurements derived from the social web are increasingly advocated and used as early indicators of article impact and usefulness. Nevertheless, there is a lack of systematic scientific evidence that altmetrics are valid proxies of either impact or utility although a few case studies have reported medium correlations between specific altmetrics and citation rates for individual journals or fields. To fill this gap, this study compares 11 altmetrics with Web of Science citations for 76 to 208,739 PubMed articles with at least one altmetric mention in each case and up to 1,891 journals per metric. It also introduces a simple sign test to overcome biases caused by different citation and usage windows. Statistically significant associations were found between higher metric scores and higher citations for articles with positive altmetric scores in all cases with sufficient evidence (Twitter, Facebook wall posts, research highlights, blogs, mainstream media and forums) except perhaps for Google+ posts. Evidence was insufficient for LinkedIn, Pinterest, question and answer sites, and Reddit, and no conclusions should be drawn about articles with zero altmetric scores or the strength of any correlation between altmetrics and citations. Nevertheless, comparisons between citations and metric values for articles published at different times, even within the same year, can remove or reverse this association and so publishers and scientometricians should consider the effect of time when using altmetrics to rank articles. Finally, the coverage of all the altmetrics except for Twitter seems to be low and so it is not clear if they are prevalent enough to be useful in practice.

828 citations


Journal ArticleDOI
TL;DR: The Canadian Hypertension Education Program reviews the hypertension literature annually and provides detailed recommendations regarding hypertension diagnosis, assessment, prevention, and treatment, and 4 new recommendations were added and 2 existing recommendations were modified this year.

683 citations


Journal ArticleDOI
31 Oct 2013-Nature
TL;DR: Any predicted increase in aridity with climate change will probably reduce the concentrations of N and C in global drylands, but increase that of P, suggesting the provision of key services provided by these ecosystems could be negatively affected.
Abstract: The biogeochemical cycles of carbon (C), nitrogen (N) and phosphorus (P) are interlinked by primary production, respiration and decomposition in terrestrial ecosystems. It has been suggested that the C, N and P cycles could become uncoupled under rapid climate change because of the different degrees of control exerted on the supply of these elements by biological and geochemical processes. Climatic controls on biogeochemical cycles are particularly relevant in arid, semi-arid and dry sub-humid ecosystems (drylands) because their biological activity is mainly driven by water availability. The increase in aridity predicted for the twenty-first century in many drylands worldwide may therefore threaten the balance between these cycles, differentially affecting the availability of essential nutrients. Here we evaluate how aridity affects the balance between C, N and P in soils collected from 224 dryland sites from all continents except Antarctica. We find a negative effect of aridity on the concentration of soil organic C and total N, but a positive effect on the concentration of inorganic P. Aridity is negatively related to plant cover, which may favour the dominance of physical processes such as rock weathering, a major source of P to ecosystems, over biological processes that provide more C and N, such as litter decomposition. Our findings suggest that any predicted increase in aridity with climate change will probably reduce the concentrations of N and C in global drylands, but increase that of P. These changes would uncouple the C, N and P cycles in drylands and could negatively affect the provision of key services provided by these ecosystems.

667 citations


Journal ArticleDOI
TL;DR: To reduce the uncertainties and to improve the precision of the predictions of the impacts of climate change and human activities on biogeochemical cycles, efforts should focus on conducting more field observation studies, integrating data within improved models, and developing new knowledge about coupling among carbon, nitrogen, and phosphorus bioge biochemical cycles.
Abstract: With a pace of about twice the observed rate of global warming, the temperature on the Qinghai-Tibetan Plateau (Earth's third pole') has increased by 0.2 degrees C per decade over the past 50years, which results in significant permafrost thawing and glacier retreat. Our review suggested that warming enhanced net primary production and soil respiration, decreased methane (CH4) emissions from wetlands and increased CH4 consumption of meadows, but might increase CH4 emissions from lakes. Warming-induced permafrost thawing and glaciers melting would also result in substantial emission of old carbon dioxide (CO2) and CH4. Nitrous oxide (N2O) emission was not stimulated by warming itself, but might be slightly enhanced by wetting. However, there are many uncertainties in such biogeochemical cycles under climate change. Human activities (e.g. grazing, land cover changes) further modified the biogeochemical cycles and amplified such uncertainties on the plateau. If the projected warming and wetting continues, the future biogeochemical cycles will be more complicated. So facing research in this field is an ongoing challenge of integrating field observations with process-based ecosystem models to predict the impacts of future climate change and human activities at various temporal and spatial scales. To reduce the uncertainties and to improve the precision of the predictions of the impacts of climate change and human activities on biogeochemical cycles, efforts should focus on conducting more field observation studies, integrating data within improved models, and developing new knowledge about coupling among carbon, nitrogen, and phosphorus biogeochemical cycles as well as about the role of microbes in these cycles.

615 citations


Journal ArticleDOI
TL;DR: New reactions enabled by a single class of ligands, phosphine-sulfonate (ortho-phosphinobenzenesulfonates), using their palladium complexes, are summarized, which have developed four unusual reactions, and three of these have produced novel types of polymers.
Abstract: Ligands, Lewis bases that coordinate to the metal center in a complex, can completely change the catalytic behavior of the metal center. In this Account, we summarize new reactions enabled by a single class of ligands, phosphine–sulfonates (ortho-phosphinobenzenesulfonates). Using their palladium complexes, we have developed four unusual reactions, and three of these have produced novel types of polymers.In one case, we have produced linear high-molecular weight polyethylene, a type of polymer that group 10 metal catalysts do not typically produce. Secondly, complexes using these ligands catalyzed the formation of linear poly(ethylene-co-polar vinyl monomers). Before the use of phosphine–sulfonate catalysts, researchers could only produce ethylene/polar monomer copolymers that have different branched structures rather than linear ones, depending on whether the polymers were produced by a radical polymerization or a group 10 metal catalyzed coordination polymerization. Thirdly, these phosphine–sulfonate ca...

406 citations


Journal ArticleDOI
TL;DR: It is shown that financial knowledge is a key determinant of wealth inequality in a stochastic life cycle model with endogenous financial knowledge accumulation, where financial knowledge enables individuals to better allocate lifetime resources in a world of uncertainty and imperfect insurance.
Abstract: Using a stochastic life cycle model with endogenous financial knowledge accumulation, we show that financial knowledge is a key determinant of wealth inequality. The mechanism we posit is that financial knowledge enables individuals to better allocate re- sources over their lifetimes in a world of uncertainty and imperfect insurance. Moreover, because of how the U.S. social insurance system works, better-educated individuals have the most to gain from investing in financial knowledge. As a result, making financial knowledge accumulation endogenous amplifies differences in accumulated retirement wealth over the life cycle. According to our estimates, from 30 to 40 percent of wealth inequality can be accounted for by financial knowledge.

388 citations


Journal ArticleDOI
TL;DR: The validity and reliability of the sport motivation scale (SMS-II) has been examined in two studies as discussed by the authors, and the structure of the SMS-II and its relation with outcomes was further examined.

339 citations


Journal ArticleDOI
TL;DR: Strong measurement partial invariance over 5 passion activity groups indicates that the same set of items is appropriate for assessing passion across a wide variety of activities--a previously untested, implicit assumption that greatly enhances practical utility.
Abstract: The passion scale, based on the dualistic model of passion, measures 2 distinct types of passion: Harmonious and obsessive passions are predictive of adaptive and less adaptive outcomes, respectively. In a substantive-methodological synergy, we evaluate the construct validity (factor structure, reliability, convergent and discriminant validity) of Passion Scale responses (N = 3,571). The exploratory structural equation model fit to the data was substantially better than the confirmatory factor analysis solution, and resulted in better differentiated (less correlated) factors. Results from a 13-model taxonomy of measurement invariance supported complete invariance (factor loadings, factor correlations, item uniquenesses, item intercepts, and latent means) over language (French vs. English; the instrument was originally devised in French, then translated into English) and gender. Strong measurement partial invariance over 5 passion activity groups (leisure, sport, social, work, education) indicates that the same set of items is appropriate for assessing passion across a wide variety of activities--a previously untested, implicit assumption that greatly enhances practical utility. Support was found for the convergent and discriminant validity of the harmonious and obsessive passion scales, based on a set of validity correlates: life satisfaction, rumination, conflict, time investment, activity liking and valuation, and perceiving the activity as a passion.

293 citations


Journal ArticleDOI
TL;DR: In this paper, the authors used a new extensive database of peat profiles across northern high latitudes to examine spatial and temporal patterns of carbon accumulation over the past millennium and found that the carbon accumulation rate in northern peatlands is linearly related to contemporary growing season length and photosynthetically active radiation, suggesting that variability in net primary productivity is more important than decomposition in determining longterm carbon accumulation.
Abstract: Peatlands are a major terrestrial carbon store and a persistent natural carbon sink during the Holocene, but there is considerable uncertainty over the fate of peatland carbon in a changing climate. It is generally assumed that higher temperatures will increase peat decay, causing a positive feedback to climate warming and contributing to the global positive carbon cycle feedback. Here we use a new extensive database of peat profiles across northern high latitudes to examine spatial and temporal patterns of carbon accumulation over the past millennium. Opposite to expectations, our results indicate a small negative carbon cycle feedback from past changes in the long-term accumulation rates of northern peatlands. Total carbon accumulated over the last 1000 yr is linearly related to contemporary growing season length and photosynthetically active radiation, suggesting that variability in net primary productivity is more important than decomposition in determining long-term carbon accumulation. Furthermore, northern peatland carbon sequestration rate declined over the climate transition from the Medieval Climate Anomaly (MCA) to the Little Ice Age (LIA), probably because of lower LIA temperatures combined with increased cloudiness suppressing net primary productivity. Other factors including changing moisture status, peatland distribution, fire, nitrogen deposition, permafrost thaw and methane emissions will also influence future peatland carbon cycle feedbacks, but our data suggest that the carbon sequestration rate could increase over many areas of northern peatlands in a warmer future.

292 citations


Journal ArticleDOI
TL;DR: The Cattell's scree test as mentioned in this paper is a graphical strategy with a non-numerical solution to determine the number of components to retain, and it is one of the most frequently used strategies for determining the principal component to retain.
Abstract: Most of the strategies that have been proposed to determine the number of components that account for the most variation in a principal components analysis of a correlation matrix rely on the analysis of the eigenvalues and on numerical solutions. The Cattell's scree test is a graphical strategy with a nonnumerical solution to determine the number of components to retain. Like Kaiser's rule, this test is one of the most frequently used strategies for determining the number of components to retain. However, the graphical nature of the scree test does not definitively establish the number of components to retain. To circumvent this issue, some numerical solutions are proposed, one in the spirit of Cattell's work and dealing with the scree part of the eigenvalues plot, and one focusing on the elbow part of this plot. A simulation study compares the efficiency of these solutions to those of other previously proposed methods. Extensions to factor analysis are possible and may be particularly useful with many low-dimensional components. Several strategies have been proposed to determine the num- ber of components that account for the most variation in a principal components analysis of a correlation matrix. Most of these rely on the analysis of the eigenvalues of the corre- lation matrix and on numerical solutions. For example, Kaiser's eigenvalue greater than one rule (Guttman, 1954; Kaiser, 1960), parallel analysis (Buja & Eyuboglu, 1992; Horn, 1965; Hoyle & Duvall, 2004), or hypothesis signifi- cance tests, like Bartlett's test (1950), make use of numerical criteria for comparison or statistical significance criteria. Independently of these numerical solutions, Cattell (1966) proposed the scree test, a graphical strategy to determine the number of components to retain. Along with the Kaiser's rule, the scree test is probably the most used strategy and it is included in almost all statistical software dealing with principal components analysis. Unfortunately, it is generally recognized that the graphical nature of the Cattell's scree test does not enable clear decision-making about the number of components to retain. The previously proposed non-graphical solutions for

Journal ArticleDOI
TL;DR: The authors examined the impact of individual dimensions of social performance (SP) on firm risk (total and idiosyncratic) using 16,599 firm-year observations over the period 1991-2007, and found that firm risk for S&P500 members is positively affected by Employee, Diversity, and Corporate Governance concerns.
Abstract: This paper examines the impact of the individual dimensions of social performance (SP) on firm risk (total and idiosyncratic) using 16,599 firm-year observations over the period 1991–2007. We find that firm risk for S&P500 members is positively affected by Employee, Diversity, and Corporate Governance concerns. On the other hand, Community (Diversity) strengths negatively (positively) affect their risk. As to non-S&P500 members, firm risk is positively affected by Employee concerns and Diversity strengths. However, firm risk of non-S&P500 members is negatively affected by Environment strengths. The direction of causation between firm risk and SP depends on the dimension examined.

Journal ArticleDOI
TL;DR: Physical exercise training leads to improved cognitive functioning and psychological well-being in frail older adults.
Abstract: Objectives.Frailty is a state of vulnerability associated with increased risks of fall, hospitalization, cognitive deficits, and psychological distress. Studies with healthy senior suggest that physical exercise can help improve cognition and quality of life. Whether frail older adults can show such benefits remains to be documented.Method.A total of 83 participants aged 61-89 years were assigned to an exercise-training group (3 times a week for 12 weeks) or a control group (waiting list). Frailty was determined by a complete geriatric examination using specific criteria. Pre- and post-test measures assessed physical capacity, cognitive performance, and quality of life. RESULTS: Compared with controls, the intervention group showed significant improvement in physical capacity (functional capacities and physical endurance), cognitive performance (executive functions, processing speed, and working memory), and quality of life (global quality of life, leisure activities, physical capacity, social/family relationships, and physical health). Benefits were overall equivalent between frail and nonfrail participants.Discussion.Physical exercise training leads to improved cognitive functioning and psychological well-being in frail older adults. Language: en

Journal ArticleDOI
TL;DR: This analysis of hundreds of boreal lakes, rivers and wetlands in Canada shows that the proportion of biologically degradable dissolved organic carbon remains constant and the photochemical degradability increases with terrestrial influence, and degradation potential increases with increasing amounts of terrestrial carbon.
Abstract: The concentrations of terrestrially derived dissolved organic carbon have been increasing throughout northern aquatic ecosystems in recent decades, but whether these shifts have an impact on aquatic carbon emissions at the continental scale depends on the potential for this terrestrial carbon to be converted into carbon dioxide. Here, via the analysis of hundreds of boreal lakes, rivers and wetlands in Canada, we show that, contrary to conventional assumptions, the proportion of biologically degradable dissolved organic carbon remains constant and the photochemical degradability increases with terrestrial influence. Thus, degradation potential increases with increasing amounts of terrestrial carbon. Our results provide empirical evidence of a strong causal link between dissolved organic carbon concentrations and aquatic fluxes of carbon dioxide, mediated by the degradation of land-derived organic carbon in aquatic ecosystems. Future shifts in the patterns of terrestrial dissolved organic carbon in inland waters thus have the potential to significantly increase aquatic carbon emissions across northern landscapes.

Journal ArticleDOI
TL;DR: In this paper, the authors build a framework to theorize about how work-nonwork boundary preferences and self-evaluation motives drive the adoption of four archetypical sets of online boundary management behaviors (Open, audience, content, and hybrid), and the consequences of these behaviors for respect and liking in professional relationships.
Abstract: As employees increasingly interact with their professional contacts on online social networks that are personal in nature, such as Facebook or Twitter, they are likely to experience a collision of their professional and personal identities that is unique to this new and expanding social space. In particular, online social networks present employees with boundary management and identity negotiation opportunities and challenges, because they invite non-tailored self-disclosure to broad audiences, while offering few of the physical and social cues that normally guide social interactions. How and why do employees manage the boundaries between their professional and personal identities in online social networks, and how do these behaviors impact the way they are regarded by professional contacts? We build a framework to theorize about how work-nonwork boundary preferences and self-evaluation motives drive the adoption of four archetypical sets of online boundary management behaviors (open, audience, content, and hybrid), and the consequences of these behaviors for respect and liking in professional relationships. Content and hybrid behaviors are more likely to increase respect and liking than open and audience behaviors; audience and hybrid behaviors are less risky for respect and liking than open and content behaviors but more difficult to maintain over time.

Journal ArticleDOI
TL;DR: The results demonstrated the candidacy of glycodendrimersomes as new mimics of biological membranes with programmable glycan ligand presentations, as supramolecular lectin blockers, vaccines, and targeted delivery devices.
Abstract: The modular synthesis of 7 libraries containing 51 self-assembling amphiphilic Janus dendrimers with the monosaccharides D-mannose and D-galactose and the disaccharide D-lactose in their hydrophilic part is reported. These unprecedented sugar-containing dendrimers are named amphiphilic Janus glycodendrimers. Their self-assembly by simple injection of THF or ethanol solution into water or buffer and by hydration was analyzed by a combination of methods including dynamic light scattering, confocal microscopy, cryogenic transmission electron microscopy, Fourier transform analysis, and micropipet-aspiration experiments to assess mechanical properties. These libraries revealed a diversity of hard and soft assemblies, including unilamellar spherical, polygonal, and tubular vesicles denoted glycodendrimersomes, aggregates of Janus glycodendrimers and rodlike micelles named glycodendrimer aggregates and glycodendrimermicelles, cubosomes denoted glycodendrimercubosomes, and solid lamellae. These assemblies are stable over time in water and in buffer, exhibit narrow molecular-weight distribution, and display dimensions that are programmable by the concentration of the solution from which they are injected. This study elaborated the molecular principles leading to single-type soft glycodendrimersomes assembled from amphiphilic Janus glycodendrimers. The multivalency of glycodendrimersomes with different sizes and their ligand bioactivity were demonstrated by selective agglutination with a diversity of sugar-binding protein receptors such as the plant lectins concanavalin A and the highly toxic mistletoe Viscum album L. agglutinin, the bacterial lectin PA-IL from Pseudomonas aeruginosa, and, of special biomedical relevance, human adhesion/growth-regulatory galectin-3 and galectin-4. These results demonstrated the candidacy of glycodendrimersomes as new mimics of biological membranes with programmable glycan ligand presentations, as supramolecular lectin blockers, vaccines, and targeted delivery devices.

Journal ArticleDOI
TL;DR: In this article, a meta-analysis of the empirical literature focusing on the conceptualization, measurement, antecedents, and consequences of e-loyalty is presented, which provides a cohesive view of online customer loyalty and helps identify potential unexplored research opportunities in this area.

Journal ArticleDOI
TL;DR: In this paper, it was shown that the fundamental group of the two-branched cover of an alternating link is left-orderable if and only if it is a trivial link with two or more components.
Abstract: Examples suggest that there is a correspondence between L-spaces and three-manifolds whose fundamental groups cannot be left-ordered. In this paper we establish the equivalence of these conditions for several large classes of manifolds. In particular, we prove that they are equivalent for any closed, connected, orientable, geometric three-manifold that is non-hyperbolic, a family which includes all closed, connected, orientable Seifert fibred spaces. We also show that they are equivalent for the twofold branched covers of non-split alternating links. To do this we prove that the fundamental group of the twofold branched cover of an alternating link is left-orderable if and only if it is a trivial link with two or more components. We also show that this places strong restrictions on the representations of the fundamental group of an alternating knot complement with values in $$\text{ Homeo}_+(S^1)$$ .

Journal ArticleDOI
TL;DR: In this article, the authors investigated the potential direct and indirect impacts of climate change on plantations and concluded that in the short to medium term changes in plantation management designed to mitigate or adapt to climate change could have a significantly greater impact on biodiversity in such plantations than the direct effects of the climate change.
Abstract: Nearly 4 % of the world’s forests are plantations, established to provide a variety of ecosystem services, principally timber and other wood products In addition to such services, plantation forests provide direct and indirect benefits to biodiversity via the provision of forest habitat for a wide range of species, and by reducing negative impacts on natural forests by offsetting the need to extract resources There is compelling evidence that climate change is directly affecting biodiversity in forests throughout the world These impacts occur as a result of changes in temperature, rainfall, storm frequency and magnitude, fire frequency, and the frequency and magnitude of pest and disease outbreaks However, in plantation forests it is not only the direct effects of climate change that will impact on biodiversity Climate change will have strong indirect effects on biodiversity in plantation forests via changes in forest management actions that have been proposed to mitigate the effects of climate change on the productive capacity of plantations These include changes in species selection (including use of species mixtures), rotation length, thinning, pruning, extraction of bioenergy feedstocks, and large scale climate change driven afforestation, reforestation, and, potentially deforestation By bringing together the potential direct and indirect impacts of climate change we conclude that in the short to medium term changes in plantation management designed to mitigate or adapt to climate change could have a significantly greater impact on biodiversity in such plantation forests than the direct effects of climate change Although this hypothesis remains to be formally tested, forest managers worldwide are already considering new approaches to plantation forestry in an effort to create forests that are more resilient to the effects of changing climatic conditions Such change presents significant risks to existing biodiversity values in plantation forests, however it also provides new opportunities to improve biodiversity values within existing and new plantation forests We conclude by suggesting future options, such as functional zoning and species mixtures applied at either the stand level or as fine-scale mosaics of single-species stands as options to improve biodiversity whilst increasing resilience to climate change

Journal ArticleDOI
01 Mar 2013-Brain
TL;DR: A stress model of chronic pain is supported suggesting that the sustained endocrine stress response observed in individuals with a smaller hippocampii induces changes in the function of the hippocampal complex that may contribute to the persistent pain states.
Abstract: Recent theories have suggested that chronic pain could be partly maintained by maladaptive physiological responses of the organism facing a recurrent stressor. The present study examined the associations between basal levels of cortisol collected over seven consecutive days, the hippocampal volumes and brain activation to thermal stimulations administered in 16 patients with chronic back pain and 18 healthy control subjects. Results showed that patients with chronic back pain have higher levels of cortisol than control subjects. In these patients, higher cortisol was associated with smaller hippocampal volume and stronger pain-evoked activity in the anterior parahippocampal gyrus, a region involved in anticipatory anxiety and associative learning. Importantly, path modelling—a statistical approach used to examine the empirical validity of propositions grounded on previous literature—revealed that the cortisol levels and phasic pain responses in the parahippocampal gyrus mediated a negative association between the hippocampal volume and the chronic pain intensity. These findings support a stress model of chronic pain suggesting that the sustained endocrine stress response observed in individuals with a smaller hippocampii induces changes in the function of the hippocampal complex that may contribute to the persistent pain states.

Journal ArticleDOI
TL;DR: MsTMIP as mentioned in this paper is a formal model intercomparison and evaluation effort focused on improving the diagnosis and attribution of carbon exchange at regional and global scales, and has a unique framework designed to isolate, interpret, and inform understanding of how model structural differences impact estimates of carbon uptake and release.
Abstract: . Terrestrial biosphere models (TBMs) have become an integral tool for extrapolating local observations and understanding of land–atmosphere carbon exchange to larger regions. The North American Carbon Program (NACP) Multi-scale synthesis and Terrestrial Model Intercomparison Project (MsTMIP) is a formal model intercomparison and evaluation effort focused on improving the diagnosis and attribution of carbon exchange at regional and global scales. MsTMIP builds upon current and past synthesis activities, and has a unique framework designed to isolate, interpret, and inform understanding of how model structural differences impact estimates of carbon uptake and release. Here we provide an overview of the MsTMIP effort and describe how the MsTMIP experimental design enables the assessment and quantification of TBM structural uncertainty. Model structure refers to the types of processes considered (e.g., nutrient cycling, disturbance, lateral transport of carbon), and how these processes are represented (e.g., photosynthetic formulation, temperature sensitivity, respiration) in the models. By prescribing a common experimental protocol with standard spin-up procedures and driver data sets, we isolate any biases and variability in TBM estimates of regional and global carbon budgets resulting from differences in the models themselves (i.e., model structure) and model-specific parameter values. An initial intercomparison of model structural differences is represented using hierarchical cluster diagrams (a.k.a. dendrograms), which highlight similarities and differences in how models account for carbon cycle, vegetation, energy, and nitrogen cycle dynamics. We show that, despite the standardized protocol used to derive initial conditions, models show a high degree of variation for GPP, total living biomass, and total soil carbon, underscoring the influence of differences in model structure and parameterization on model estimates.

Journal ArticleDOI
TL;DR: This overview will focus on the prevalence of CSA, the associated mental health outcomes, and the preventive strategies to prevent CSA from happening in the first place.
Abstract: Although child sexual abuse (CSA) is recognized as a serious violation of human well-being and of the law, no community has yet developed mechanisms that ensure that none of their youth will be sexually abused. CSA is, sadly, an international problem of great magnitude that can affect children of all ages, sexes, races, ethnicities, and socioeconomic classes. Upon invitation, this current publication aims at providing a brief overview of a few lessons we have learned from CSA scholarly research as to heighten awareness of mental health professionals on this utmost important and widespread social problem. This overview will focus on the prevalence of CSA, the associated mental health outcomes, and the preventive strategies to prevent CSA from happening in the first place.

Journal ArticleDOI
TL;DR: This review provides a survey of the numerous aromatic architectures generated for the multivalent presentation of relevant carbohydrates using covalent attachment or supramolecular self-assemblies using modern synthetic procedures with a particular emphasis on powerful organometallic methodologies.
Abstract: Glycan–protein interactions are of utmost importance in several biological phenomena. Although the variety of carbohydrate residues in mammalian cells is limited to less than a dozen different sugars, their spatial topographical presentation in what is now associated as the “glycocodes” provides the fundamental keys for specific and high affinity “lock-in” recognition events associated with a wide range of pathologies. Toward deciphering our understanding of these glycocodes, chemists have developed new creative tools that included dendrimer chemistry in order to provide monodisperse multivalent glycoconjugates. This review provides a survey of the numerous aromatic architectures generated for the multivalent presentation of relevant carbohydrates using covalent attachment or supramolecular self-assemblies. The basic concepts toward their controlled syntheses will be described using modern synthetic procedures with a particular emphasis on powerful organometallic methodologies. The large variety of dendritic aromatic scaffolds, together with a brief survey of their unique biophysical and biological properties will be critically reviewed. The distinctiveness of the resulting multivalent glycoarchitectures, encompassing glycoclusters, glycodendrimers and molecularly defined self-assemblies, in forming well organized cross-linked lattices with multivalent carbohydrate binding proteins (lectins) together with their photophysical, medical, and imaging properties will also be briefly highlighted. The topic will be presented in increasing order of aromatic backbone complexities and will end with fullerenes together with self-assembled nanostructures, thus complementing the various scaffolds described in this special thematic issue dedicated to multivalent glycoscience.

Journal ArticleDOI
TL;DR: This work highlights three future research priorities: systematic theoretical analysis of the evolutionary properties of learning rules; detailed empirical study of how animals learn in nonforaging contexts; and analysis of individual differences in learning rules and their associated fitness consequences.
Abstract: Behavioral ecologists have long been comfortable assuming that genetic architecture does not constrain which phenotypescan evolve (the "phenotypic gambit"). For flexible behavioral traits, however, solutions to adaptive problems are reached not only by genetic evolution but also by behavioral changes within an individual's lifetime, via psychological mechanisms such as learning. Standard optimality approaches ignore these mechanisms, implicitly assuming that they do not constrain the expression of adaptive behavior. This assumption, which we dub the behavioral gambit, is sometimes wrong: evolved psychological mechanisms can prevent animals from behaving optimally in specific situations. To understand the functional basis of behavior, we would do better by considering the underlying mechanisms, rather than the behavioral outcomes they produce, as the target of selection. This change of focus yields new, testable predictions about evolutionary equilibria, the development of behavior, and the properties of cognitive systems. Studies on the evolution of learning rules hint at the potential insights to be gained, but such mechanism-based approaches are underexploited. We highlight three future research priorities: (1) systematic theoretical analysis of the evolutionary properties of learning rules; (2) detailed empirical study of how animals learn in nonforaging contexts;and (3) analysis of individual differences in learning rules and their associated fitness consequences.

Journal ArticleDOI
TL;DR: In this paper, the authors investigate an ICT public-private innovation cluster that fails to collaborate and explore how geographic, institutional, organizational, cognitive and social proximities interplay.

Journal ArticleDOI
TL;DR: Investigation of parent-child communication regarding adolescent unsupervised activities develops over the course of adolescence revealed curvilinear developmental changes that differed for boys and girls.
Abstract: This study examined how parent–child communication regarding adolescent unsupervised activities develops over the course of adolescence. We used questionnaire data from 390 adolescents (58% girls; 90% European Canadian) who were followed from age 12 to 19. Latent growth curve modeling revealed curvilinear developmental changes that differed for boys and girls. From age 14 to 19 (but not from age 12 to 14) a linear decrease in parental control was found for both genders. For girls, parent–child communication decreased in early adolescence, as indicated by decreasing parental solicitation, decreasing adolescent disclosure, and increasing secrecy. Girls’ communication with parents intensified in middle adolescence, as indicated by increasing parental solicitation, increasing adolescent disclosure, and decreasing adolescent secrecy. For boys, disclosure declined in early adolescence, but secrecy and solicitation were stable throughout adolescence. Parental knowledge decreased from age 12 to 19 for both genders but was temporarily stable for middle adolescent girls. The meaning of these developmental changes, their timing, and gender differences are discussed.

Journal ArticleDOI
TL;DR: The CRCM5 model as discussed by the authors is based on ERA re-analyses for the period 1984-2008 over the African continent following the CORDEX experimental protocol, and the model succeeds in reproducing the main features of the geographical distribution and seasonal cycle of temperature and precipitation, the diurnal cycle of precipitation and the West African Monsoon (WAM).
Abstract: The new fifth-generation Regional Climate Model (CRCM5) was driven by ERA reanalyses for the period 1984–2008 over the African continent following the CORDEX experimental protocol. Overall the model succeeds in reproducing the main features of the geographical distribution and seasonal cycle of temperature and precipitation, the diurnal cycle of precipitation, and the West African Monsoon (WAM). Biases in surface temperature and precipitation are discussed in relation with some circulation defects noted in the simulation. In the African regions near the equator, the model successfully reproduces the double peak of rainfall due to the double passage of the tropical rainbelt, although it better simulates the magnitude and timing of the second peak of precipitation. CRCM5 captures the timing of the monsoon onset for the Sahel region but underestimates the magnitude of precipitation. The simulated diurnal cycle is quite well simulated for all of the regions, but is always somewhat in advance for the timing of rainfall peak. In boreal summer the CRCM5 simulation exhibits a weak cold bias over the Sahara and the maximum temperature is located too far south, resulting in a southward bias in the position of the Saharan Heat Low. The region of maximum ascent in the deep meridional circulation of the Hadley cell is well located in the CRCM5 simulation, but it is somewhat too narrow. The core of the African Easterly Jet is of the right strength and almost at the right height, but it is displayed slightly southward, as a consequence of the southward bias in the position of the Saharan Heat Low and the thermal wind relationship. These biases appear to be germane to the WAM rainfall band being narrower and not moving far enough northward, resulting in a dry bias in the Sahel.

Journal ArticleDOI
TL;DR: A descriptive review reveals many positive signs of rigor such as ensuring the anonymity of experts and providing clear and precise instructions to participants, Nevertheless, there are still several areas for improvement, such as reporting response and retention rates, instrument pretesting, and explicitly justifying modifications to the ranking-type Delphi method.

Journal ArticleDOI
TL;DR: It is confirmed that autonomic dysfunction can occur early in neurodegenerative synucleinopathy, even as long as 20 years before defined disease.
Abstract: Pathologic staging systems suggest that autonomic dysfunction may be an early manifestation of Parkinson's disease and dementia with Lewy bodies. However, direct evidence is limited, and no prospective studies have measured when autonomic dysfunction starts before disease. Patients with idiopathic rapid eye movement (REM) sleep behavior disorder are at very high risk of developing neurodegenerative synucleinopathy, providing an opportunity to directly observe the development of autonomic dysfunction from prodromal stages of neurodegeneration. Patients with idiopathic REM sleep behavior disorder were followed annually in a prospective cohort that was established in 2004. Urinary, orthostatic, erectile, and constipation symptoms and systolic blood pressure drop from lying to standing were assessed annually. Patients who eventually developed defined synucleinopathy were compared with age-matched controls. The evolution of autonomic measures was assessed with regression analysis to determine when markers first deviated from control values. Sensitivity and specificity of autonomic markers for identification of prodromal disease were calculated. Of 91 patients, 32 developed disease. In prodromal stages, there was substantial autonomic dysfunction observable at least 5 years before diagnosis. On regression analysis, autonomic dysfunction appeared to progress slowly over prodromal periods. The estimated onset of autonomic dysfunction ranged from 11 years to 20 years, and systolic drop (20.4 years) and constipation (15.3 years) had the earliest estimates. Systolic drop, erectile dysfunction, and constipation could identify disease up to 5 years before diagnosis with sensitivity ranging from 50% to 90%. By directly observing development of neurodegenerative synucleinopathy, we confirmed that autonomic dysfunction can occur early in neurodegenerative synucleinopathy, even as long as 20 years before defined disease. © 2013 Movement Disorder Society.

Journal ArticleDOI
TL;DR: It is concluded that it is possible to identify indicators and match them with verifier variables to support inclusion of social and cultural values in planning.
Abstract: Policies on economic use of natural resources require considerations to social and cultural values. In order to make those concrete in a planning context, this paper aims to interpret social and cultural criteria, identify indicators, match these with verifier variables and visualize them on maps. Indicators were selected from a review of scholarly work and natural resource policies, and then matched with verifier variables available for Sweden’s 290 municipalities. Maps of the spatial distribution of four social and four cultural verifier variables were then produced. Consideration of social and cultural values in the studied natural resource use sectors was limited. The spatial distribution of the verifier variables exhibited a general divide between northwest and south Sweden, and regional rural and urban areas. We conclude that it is possible to identify indicators and match them with verifier variables to support inclusion of social and cultural values in planning.