scispace - formally typeset
Search or ask a question
Institution

Université libre de Bruxelles

EducationBrussels, Belgium
About: Université libre de Bruxelles is a education organization based out in Brussels, Belgium. It is known for research contribution in the topics: Population & Breast cancer. The organization has 24974 authors who have published 56969 publications receiving 2084303 citations. The organization is also known as: ULB.


Papers
More filters
Journal ArticleDOI
TL;DR: The results are discussed in terms of a possible organization of the antiparallel beta-sheets in Abeta oligomers, which may be related to reported effects of these highly toxic species in the amyloid pathogenesis associated with AD.
Abstract: AD (Alzheimer's disease) is linked to Abeta (amyloid beta-peptide) misfolding. Studies demonstrate that the level of soluble Abeta oligomeric forms correlates better with the progression of the disease than the level of fibrillar forms. Conformation-dependent antibodies have been developed to detect either Abeta oligomers or fibrils, suggesting that structural differences between these forms of Abeta exist. Using conditions which yield well-defined Abeta-(1-42) oligomers or fibrils, we studied the secondary structure of these species by ATR (attenuated total reflection)-FTIR (Fourier-transform infrared) spectroscopy. Whereas fibrillar Abeta was organized in a parallel beta-sheet conformation, oligomeric Abeta displayed distinct spectral features, which were attributed to an antiparallel beta-sheet structure. We also noted striking similarities between Abeta oligomers spectra and those of bacterial outer membrane porins. We discuss our results in terms of a possible organization of the antiparallel beta-sheets in Abeta oligomers, which may be related to reported effects of these highly toxic species in the amyloid pathogenesis associated with AD.

431 citations

Journal ArticleDOI
William D. Travis1, Hisao Asamura2, Alexander A. Bankier3, Mary Beth Beasley4, Frank C. Detterbeck5, Douglas B. Flieder6, Jin Mo Goo7, Heber MacMahon8, David P. Naidich9, Andrew G. Nicholson10, Charles A. Powell, Mathias Prokop11, Ramón Rami-Porta12, Valerie W. Rusch1, Paul Van Schil, Yasushi Yatabe, Peter Goldstraw10, David Ball13, David G. Beer14, Ricardo Beyruti15, Vanessa Bolejack16, Kari Chansky16, John Crowley16, Wilfried Eberhardt17, John G. Edwards18, Françoise Galateau-Salle19, Dorothy Giroux16, Fergus V. Gleeson20, Patti A. Groome21, James Huang1, Catherine Kennedy22, Jhingook Kim23, Young Tae Kim24, Laura Kingsbury16, Haruhiko Kondo25, Mark Krasnik26, Kaoru Kubota27, Antoon Lerut28, Gustavo Lyons29, Mirella Marino, Edith M. Marom30, Jan P. van Meerbeeck31, Alan Mitchell16, Takashi Nakano32, Anna K. Nowak33, Michael D Peake34, Thomas W. Rice35, Kenneth E. Rosenzweig36, Enrico Ruffini37, Nagahiro Saijo, Jean-Paul Sculier38, Lynn Shemanski16, Kelly G. Stratton16, Kenji Suzuki39, Yuji Tachimori40, Charles F. Thomas41, William D. Travis1, Ming-Sound Tsao42, Andrew T. Turrisi43, Johan Vansteenkiste28, Hirokazu Watanabe, Yi-Long Wu, Paul Baas44, Jeremy J. Erasmus30, Seiki Hasegawa32, Kouki Inai45, Kemp H. Kernstine46, Hedy L. Kindler8, Lee M. Krug1, Kristiaan Nackaerts28, Harvey I. Pass9, David C. Rice30, Conrad Falkson21, Pier Luigi Filosso37, Giuseppe Giaccone47, Kazuya Kondo48, Marco Lucchi49, Meinoshin Okumura50, Eugene H. Blackstone35 
TL;DR: Codes for the primary tumor categories of AIS and minimally invasive adenocarcinoma (MIA) and a uniform way to measure tumor size in part‐solid tumors for the eighth edition of the tumor, node, and metastasis classification of lung cancer are proposed.

431 citations

Journal ArticleDOI
TL;DR: The selection of the path is shown to be a collective process whereby trail laying and following amplifies small initial differences in the traffic on each path caused by these three mechanisms, and the foragers show no significant tendency to follow the path they used previously.

431 citations

Journal ArticleDOI
TL;DR: In this paper, the evolution of twinning and texture in two Mg-based (+Al, Mn, Zn) alloys was investigated using uniaxial tension, unioxial compression and ring hoop tension testing at temperatures from ambient to 250°C and a strain rate of 0.1 s−1.

431 citations


Authors

Showing all 25206 results

NameH-indexPapersCitations
Karl J. Friston2171267217169
Yi Chen2174342293080
David Miller2032573204840
Jing Wang1844046202769
H. S. Chen1792401178529
Jie Zhang1784857221720
Jasvinder A. Singh1762382223370
D. M. Strom1763167194314
J. N. Butler1722525175561
Andrea Bocci1722402176461
Bradley Cox1692150156200
Marc Weber1672716153502
Hongfang Liu1662356156290
Guenakh Mitselmakher1651951164435
Yang Yang1642704144071
Network Information
Related Institutions (5)
University of Paris
174.1K papers, 5M citations

96% related

Utrecht University
139.3K papers, 6.2M citations

93% related

University of Amsterdam
140.8K papers, 5.9M citations

93% related

Centre national de la recherche scientifique
382.4K papers, 13.6M citations

93% related

Sapienza University of Rome
155.4K papers, 4.3M citations

93% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023119
2022411
20213,194
20203,051
20192,751
20182,609