Institution
Université libre de Bruxelles
Education•Brussels, Belgium•
About: Université libre de Bruxelles is a education organization based out in Brussels, Belgium. It is known for research contribution in the topics: Population & Breast cancer. The organization has 24974 authors who have published 56969 publications receiving 2084303 citations. The organization is also known as: ULB.
Topics: Population, Breast cancer, Context (language use), Receptor, Cancer
Papers published on a yearly basis
Papers
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TL;DR: Bisphosphonate use is a major therapeutic advance in the management of the skeletal morbidity caused by metastatic breast cancer or multiple myeloma, although many questions remain unanswered, notably regarding the optimal selection of patients and the duration of treatment.
Abstract: PURPOSEThe purpose of this article is to review the recent data on bisphosphonate use in oncology and to provide some guidelines on the indications for their use in cancer patients.DESIGNThe group consensus reached by experts on the rationale for the use of bisphosphonates in cancer patients and their current indications for the treatment of tumor-induced hypercalcemia and metastatic bone pain in advanced disease and for the prevention of the complications of multiple myeloma and of metastatic bone disease are reviewed.RESULTSBisphosphonates are potent inhibitors of tumor-induced osteoclast-mediated bone resorption. They now constitute the standard treatment for cancer hypercalcemia, for which we recommend a dose of 1,500 mg of clodronate or 90 mg of pamidronate; the latter compound is more potent and has a longer lasting effect. Intravenous bisphosphonates exert clinically relevant analgesic effects in patients with metastatic bone pain. Regular pamidronate infusions can also achieve a partial objective ...
361 citations
TL;DR: In this large European study, patients with cancer were more often admitted to the ICU for sepsis and respiratory complications than other ICU patients, whereas patients with haematological cancer had a worse outcome.
Abstract: Introduction
Increasing numbers of cancer patients are being admitted to the intensive care unit (ICU), either for cancer-related complications or treatment-associated side effects, yet there are relatively few data concerning the epidemiology and prognosis of cancer patients admitted to general ICUs. The aim of this study was to assess the characteristics of critically ill cancer patients, and to evaluate their prognosis.
361 citations
TL;DR: In this paper, the capabilities of the CERN Large Hadron Collider (LHC) experiment to explore the rich heavy-ion physics program offered by the LHC are presented, and the potential of the CMS experiment to carry out a series of representative Pb-Pb measurements.
Abstract: This report presents the capabilities of the CMS experiment to explore the rich heavy-ion physics programme offered by the CERN Large Hadron Collider (LHC). The collisions of lead nuclei at energies , will probe quark and gluon matter at unprecedented values of energy density. The prime goal of this research is to study the fundamental theory of the strong interaction ? Quantum Chromodynamics (QCD) ? in extreme conditions of temperature, density and parton momentum fraction (low-x).This report covers in detail the potential of CMS to carry out a series of representative Pb-Pb measurements. These include bulk observables, (charged hadron multiplicity, low pT inclusive hadron identified spectra and elliptic flow) which provide information on the collective properties of the system, as well as perturbative probes such as quarkonia, heavy-quarks, jets and high pT hadrons which yield tomographic information of the hottest and densest phases of the reaction.
361 citations
TL;DR: This paper introduces a self-assembling and self-organizing artifact, called a swarm-bot, composed of a swarm of s-bots, mobile robots with the ability to connect to and to disconnect from each other.
Abstract: In this paper, we introduce a self-assembling and self-organizing artifact, called a swarm-bot, composed of a swarm of s-bots, mobile robots with the ability to connect to and to disconnect from each other. We discuss the challenges involved in controlling a swarm-bot and address the problem of synthesizing controllers for the swarm-bot using artificial evolution. Specifically, we study aggregation and coordinated motion of the swarm-bot using a physics-based simulation of the system. Experiments, using a simplified simulation model of the s-bots, show that evolution can discover simple but effective controllers for both the aggregation and the coordinated motion of the swarm-bot. Analysis of the evolved controllers shows that they have properties of scalability, that is, they continue to be effective for larger group sizes, and of generality, that is, they produce similar behaviors for configurations different from those they were originally evolved for. The portability of the evolved controllers to real s-bots is tested using a detailed simulation model which has been validated against the real s-bots in a companion paper in this same special issue.
360 citations
TL;DR: The recent way in which the expression of galectins and galectin-binding sites may affect the behavior of a variety of human neoplastic tissues is discussed.
360 citations
Authors
Showing all 25206 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Karl J. Friston | 217 | 1267 | 217169 |
| Yi Chen | 217 | 4342 | 293080 |
| David Miller | 203 | 2573 | 204840 |
| Jing Wang | 184 | 4046 | 202769 |
| H. S. Chen | 179 | 2401 | 178529 |
| Jie Zhang | 178 | 4857 | 221720 |
| Jasvinder A. Singh | 176 | 2382 | 223370 |
| D. M. Strom | 176 | 3167 | 194314 |
| J. N. Butler | 172 | 2525 | 175561 |
| Andrea Bocci | 172 | 2402 | 176461 |
| Bradley Cox | 169 | 2150 | 156200 |
| Marc Weber | 167 | 2716 | 153502 |
| Hongfang Liu | 166 | 2356 | 156290 |
| Guenakh Mitselmakher | 165 | 1951 | 164435 |
| Yang Yang | 164 | 2704 | 144071 |