Université Nantes Angers Le Mans

About: Université Nantes Angers Le Mans is a education organization based out in Nantes, France. It is known for research contribution in the topics: Geology & Population. The organization has 434 authors who have published 249 publications receiving 7208 citations. The organization is also known as: PRES Universite Nantes Angers Le Mans.

Comparison of different liquid chromatography stationary phases in LC‐HRMS metabolomics for the detection of recombinant growth hormone doping control

Abstract: Growth hormone (GH) is a polypeptide suspected of being used in horse racing to speed up physical performances. Despite scientific advances in the recent years, the control of its administration remains difficult. In order to improve it, a metabolomics study through LC-high resolution mass spectrometry measurements was recently initiated to assess the metabolic perturbations caused by recombinant equine growth hormone administration. Few tens of ions not identified structurally were highlighted as compounds responsible for the modification of metabolic profiling observed in treated animals. This previous work was based on the use of Uptisphere Strategy NEC as the chromatographic column. In parallel, more and more metabolomics studies showed the interest of the use of new chromatographic supports such as hydrophilic interaction chromatography for the analysis of polar compounds. It is in this context that an investigation was conducted on Uptisphere HDO and Luna hydrophilic interaction chromatography stationary phases to generate and process urinary metabolomics fingerprints, which could allow to establish a comparison with Uptisphere Strategy NEC. The chromatographic column the most adapted for the detection of new biomarkers of GH administration has been used to set up a relevant statistical model based on the analysis of more than hundred biological samples.

Inovatividade, envolvimento, atitude e experiência na adoção da compra on-line

Abstract: This work seeks to analyze the inter-relationships that exist between innovation, involvement and attitude in the decomposed model of the Theory of Planned Behavior (TPB), as applied in social psychology, and experience of using the Internet in the process of buying on-line. An integrative model was prepared that made it possible to explain the relationship that exists between these factors and purchasing from the Internet. A field survey was undertaken with a non-probabilistic sample of students. A multivariate structural equation modeling method was used and applied by the Partial Least Squares (PLS) technique for checking, explaining and comparing the relationship between the constructs. The results show that intention to buy via the Internet is directly influenced by attitude and innovativeness, and attitude is influenced by involvement. No relationship was found between experience in using the Internet and buying from it.

Study of Influence of Operating Parameters on Braking Friction and Rolling Resistance

Abstract: Tire–road interaction addresses safety with respect to braking friction and energy efficiency in the context of rolling resistance. These phenomena are coherent, but their engineering solutions can be contradictory. For example, highly skid-resistant surfaces may not be ideal for fuel economy, but surfaces with low rolling resistance may be prone to skidding. Several experimental and numerical studies have investigated the individual phenomena, but insufficient attention has been paid to studying them coherently. The present study computed braking friction and rolling resistance for various operating parameters and their coherent response for each parameter with the use of a thermomechanical contact algorithm. Micromechanical finite element simulations of a rolling or braking pneumatic tire against selected asphalt concrete surfaces were performed for various operating conditions, such as tire load, inflation pressure, speed, and ambient air and pavement temperatures. The coefficients of braking friction ...