Institution
University College Cork
Education•Cork, Ireland•
About: University College Cork is a education organization based out in Cork, Ireland. It is known for research contribution in the topics: Population & Irish. The organization has 12056 authors who have published 28452 publications receiving 958414 citations. The organization is also known as: Coláiste na hOllscoile Corcaigh & National University of Ireland, Cork.
Topics: Population, Irish, Gut flora, Microbiome, Casein
Papers published on a yearly basis
Papers
More filters
••
University of Bristol1, McGill University Health Centre2, Norwegian Institute of Public Health3, University College London4, University of Leicester5, National Institute for Health and Welfare6, University of Helsinki7, University Medical Center Groningen8, Greifswald University Hospital9, University of Western Australia10, University of Edinburgh11, Norwegian University of Science and Technology12, University College Cork13, University of Glasgow14, McGill University15
TL;DR: The technical implementation of DataSHIELD is described, using a modified R statistical environment linked to an Opal database deployed behind the computer firewall of each DC, which is currently used by the Healthy Obese Project and the Environmental Core Project for the federated analysis of 10 data sets across eight European countries.
Abstract: Background: Research in modern biomedicine and social science requires sample sizes so large that they can often only be achieved through a pooled co-analysis of data from several studies. But the pooling of information from individuals in a central database that may be queried by researchers raises important ethico-legal questions and can be controversial. In the UK this has been highlighted by recent debate and controversy relating to the UK’s proposed ‘care.data’ initiative, and these issues reflect important societal and professional concerns about privacy, confidentiality and intellectual property. DataSHIELD provides a novel technological solution that can circumvent some of the most basic challenges in facilitating the access of researchers and other healthcare professionals to individual-level data.
Methods: Commands are sent from a central analysis computer (AC) to several data computers (DCs) storing the data to be co-analysed. The data sets are analysed simultaneously but in parallel. The separate parallelized analyses are linked by non-disclosive summary statistics and commands transmitted back and forth between the DCs and the AC. This paper describes the technical implementation of DataSHIELD using a modified R statistical environment linked to an Opal database deployed behind the computer firewall of each DC. Analysis is controlled through a standard R environment at the AC.
Results: Based on this Opal/R implementation, DataSHIELD is currently used by the Healthy Obese Project and the Environmental Core Project (BioSHaRE-EU) for the federated analysis of 10 data sets across eight European countries, and this illustrates the opportunities and challenges presented by the DataSHIELD approach.
Conclusions: DataSHIELD facilitates important research in settings where: (i) a co-analysis of individual-level data from several studies is scientifically necessary but governance restrictions prohibit the release or sharing of some of the required data, and/or render data access unacceptably slow; (ii) a research group (e.g. in a developing nation) is particularly vulnerable to loss of intellectual property—the researchers want to fully share the information held in their data with national and international collaborators, but do not wish to hand over the physical data themselves; and (iii) a data set is to be included in an individual-level co-analysis but the physical size of the data precludes direct transfer to a new site for analysis.
187 citations
••
TL;DR: In this article, 3D printing was investigated for food applications, using a commercially available processed cheese as the printing material, after melting at 75°C for 12min, the processed cheese was printed using a modified commercial 3D printer at low or high extrusion rates.
186 citations
•
01 Mar 2011TL;DR: In this article, the authors present a framework of critical theory based on metatheoretical foundations and apply it to contemporary critical theory and pragmatism, including the Immanent Transcendence as key concept.
Abstract: Part I: Metatheoretical foundations 1. Classical Foundations 2. Appropriation of the Classical Foundations 3. Contemporary Critical Theory and Pragmatism 4. Immanent Transcendence as Key Concept Part II: Methodology 5. Contemporary Critical Theorists on Methodology 6. The Methodological Framework of Critical Theory 7. Varieties of Critique: Critical Theory Compared 8. Methodology in Action
186 citations
••
07 Aug 2002TL;DR: Modulation schemes using one and two chaotic basis functions, as well as coherent and noncoherent correlation receivers, are discussed and the performance of differential chaos shift keying in multipath channels is characterized.
Abstract: This paper provides a review of the principles of chaotic digital communications using correlator receivers. Modulation schemes using one and two chaotic basis functions, as well as coherent and noncoherent correlation receivers, are discussed. The performance of differential chaos shift keying (DCSK) in multipath channels is characterized. Results are presented for DCSK with multiuser capability and multiple bits per symbol.
186 citations
••
TL;DR: Weiss et al. as discussed by the authors showed that the hop-pings can occur at a codon 1 base removed from the original in-frame codon, with a resultant frameshift.
186 citations
Authors
Showing all 12300 results
Name | H-index | Papers | Citations |
---|---|---|---|
Stephen J. O'Brien | 153 | 1062 | 93025 |
James J. Collins | 151 | 669 | 89476 |
J. Wouter Jukema | 124 | 785 | 61555 |
John F. Cryan | 124 | 723 | 58938 |
Fergus Shanahan | 117 | 705 | 51963 |
Timothy G. Dinan | 116 | 689 | 60561 |
John M. Starr | 116 | 695 | 48761 |
Gordon G. Wallace | 114 | 1267 | 69095 |
Colin Hill | 112 | 693 | 54484 |
Robert Clarke | 111 | 512 | 90049 |
Douglas B. Kell | 111 | 634 | 50335 |
Thomas Bein | 109 | 677 | 42800 |
Steven C. Hayes | 106 | 450 | 51556 |
Åke Borg | 105 | 444 | 53835 |
Eamonn Martin Quigley | 103 | 685 | 39585 |