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Institution

University of Aberdeen

EducationAberdeen, United Kingdom
About: University of Aberdeen is a education organization based out in Aberdeen, United Kingdom. It is known for research contribution in the topics: Population & Randomized controlled trial. The organization has 21174 authors who have published 49962 publications receiving 2105479 citations. The organization is also known as: Aberdeen University.


Papers
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Journal ArticleDOI
TL;DR: These findings considerably challenge the accepted view of the microbial communities involved in global nitrogen cycling and the quantitative contribution of Archaea to nitrification in marine and terrestrial environments remains to be elucidated.

361 citations

Journal ArticleDOI
TL;DR: This dataset substantially improves the coverage of rumen microbial genomes in the public databases and represents a valuable resource for biomass-degrading enzyme discovery and studies of the rumen microbiome.
Abstract: The cow rumen is adapted for the breakdown of plant material into energy and nutrients, a task largely performed by enzymes encoded by the rumen microbiome Here we present 913 draft bacterial and archaeal genomes assembled from over 800 Gb of rumen metagenomic sequence data derived from 43 Scottish cattle, using both metagenomic binning and Hi-C-based proximity-guided assembly Most of these genomes represent previously unsequenced strains and species The draft genomes contain over 69,000 proteins predicted to be involved in carbohydrate metabolism, over 90% of which do not have a good match in public databases Inclusion of the 913 genomes presented here improves metagenomic read classification by sevenfold against our own data, and by fivefold against other publicly available rumen datasets Thus, our dataset substantially improves the coverage of rumen microbial genomes in the public databases and represents a valuable resource for biomass-degrading enzyme discovery and studies of the rumen microbiome

360 citations

Journal ArticleDOI
TL;DR: In this paper, the past change of the East Asian monsoon since 20 Ma using samples from Ocean Drilling Program (ODP) Site 1146 in the northern South China Sea based on a multi-proxy approach including a monomineralic quartz isolation procedure, identification of clay minerals by X-ray Diffraction (XRD) and grain-size analysis of isolated terrigenous materials.

360 citations

Journal ArticleDOI
TL;DR: A systematic review synthesises the extant research evidence on the relative strengths of various selection methods and offers a research agenda and identifies key considerations to inform policy and practice in the next 50 years.
Abstract: Acknowledgements the authors thank the UK General Medical Council (GMC) for commissioning an initial rapid review of the literature on selection and widening access to medicine in 2013. Further thanks are due to the UK Medical Schools Council (MSC) for commissioning a significantly updated review of selection methods in 2014, funding for which was provided by Health Education England (HEE) and the Office for Fair Access (OFFA). Working together on both of these projects encouraged us to further develop our ideas and produce an updated systematic review for publication in 2015. We also thank those who contributed to the original project funded by the GMC, notably John McLachlan, Member of the Centre for Medical Education Research, Durham University, and Emma Dunlop, Medical Admissions, University of Aberdeen. Funding funding was provided by HEE and the OFFA.

360 citations

Journal ArticleDOI
TL;DR: It is argued that the HDL is a major constraint operating on the expenditure side of the energy balance equation, and that processes that generate heat compete and trade-off within a total boundary defined by heat dissipation capacity, rather than competing for limited energy supply.
Abstract: Summary 1. The role of energy in ecological processes has hitherto been considered primarily from the standpoint that energy supply is limited. That is, traditional resource-based ecological and evolutionary theories and the recent ‘metabolic theory of ecology’ (MTE) all assume that energetic constraints operate on the supply side of the energy balance equation. 2. For endothermic animals, we provide evidence suggesting that an upper boundary on total energy expenditure is imposed by the maximal capacity to dissipate body heat and therefore avoid the detrimental consequences of hyperthermia – the heat dissipation limit (HDL) theory. We contend that the HDL is a major constraint operating on the expenditure side of the energy balance equation, and that processes that generate heat compete and trade-off within a total boundary defined by heat dissipation capacity, rather than competing for limited energy supply. 3. The HDL theory predicts that daily energy expenditure should scale in relation to body mass (Mb) with an exponent of about 0AE63. This contrasts the prediction of the MTE of an exponent of 0AE75. 4. We compiled empirical data on field metabolic rate (FMR) measured by the doubly-labelled water method, and found that they scale to Mb with exponents of 0AE647 in mammals and 0AE658 in birds, not significantly different from the HDL prediction (P >0 AE05) but lower than predicted by the MTE (P <0 AE001). The same statistical result was obtained using phylogenetically independent contrasts analysis. Quantitative predictions of the model matched the empirical data for both mammals and birds. There was no indication of curvature in the relationship between Loge FMR and Loge Mb. 5. Together, these data provide strong support for the HDL theory and allow us to reject the MTE, at least when applied to endothermic animals. 6. The HDL theory provides a novel conceptual framework that demands a reframing of our views of the interplay between energy and the environment in endothermic animals, and provides many new interpretations of ecological and evolutionary phenomena.

360 citations


Authors

Showing all 21424 results

NameH-indexPapersCitations
Paul M. Thompson1832271146736
Feng Zhang1721278181865
Ian J. Deary1661795114161
Peter A. R. Ade1621387138051
David W. Johnson1602714140778
Pete Smith1562464138819
Naveed Sattar1551326116368
John R. Hodges14981282709
Ruth J. F. Loos14264792485
Alan J. Silman14170892864
Michael J. Keating140116976353
David Price138168793535
John D. Scott13562583878
Aarno Palotie12971189975
Rajat Gupta126124072881
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023141
2022362
20212,195
20202,118
20191,846
20181,894