Institution
University of Aberdeen
Education•Aberdeen, United Kingdom•
About: University of Aberdeen is a education organization based out in Aberdeen, United Kingdom. It is known for research contribution in the topics: Population & Randomized controlled trial. The organization has 21174 authors who have published 49962 publications receiving 2105479 citations. The organization is also known as: Aberdeen University.
Papers published on a yearly basis
Papers
More filters
••
University of Oxford1, Trinity College, Dublin2, University of Paris3, École normale supérieure de Lyon4, Max Planck Society5, Texas A&M University6, Aristotle University of Thessaloniki7, Queen's University Belfast8, Stockholm University9, Hungarian Academy of Sciences10, Russian Academy of Sciences11, University of Rennes12, University of Aberdeen13, University of Liverpool14
TL;DR: Results suggest that dogs may have been domesticated independently in Eastern and Western Eurasia from distinct wolf populations, and East Eurasian dogs were then possibly transported to Europe with people, where they partially replaced European Paleolithic dogs.
Abstract: The geographic and temporal origins of dogs remain controversial. We generated genetic sequences from 59 ancient dogs and a complete (28x) genome of a late Neolithic dog (dated to ~4800 calendar years before the present) from Ireland. Our analyses revealed a deep split separating modern East Asian and Western Eurasian dogs. Surprisingly, the date of this divergence (~14,000 to 6400 years ago) occurs commensurate with, or several millennia after, the first appearance of dogs in Europe and East Asia. Additional analyses of ancient and modern mitochondrial DNA revealed a sharp discontinuity in haplotype frequencies in Europe. Combined, these results suggest that dogs may have been domesticated independently in Eastern and Western Eurasia from distinct wolf populations. East Eurasian dogs were then possibly transported to Europe with people, where they partially replaced European Paleolithic dogs.
329 citations
••
TL;DR: The clinical effectiveness and cost-effectiveness of using CSII to treat diabetes and to update the previous assessment report by reviewing evidence that has emerged since the last appraisal, and to take account of developments in alternative therapies, in particular the long-acting analogue insulins.
Abstract: Based on the totality of evidence, using observational studies to supplement the limited data from randomised trials against best MDI, CSII provides some advantages over MDI in T1DM for both children and adults. However, there was no evidence that CSII is better than analogue-based MDI in T2DM or in pregnancy. Further trials with larger numbers and longer durations comparing CSII and optimised MDI in adults, adolescents and children are needed. In addition, there should be a trial of CSII versus MDI with similar provision of structured education in both arms. A trial is also needed for pregnant women with pre-existing diabetes, to investigate using CSII to the best effect.
328 citations
••
TL;DR: A circuit for detecting timing errors between a binary signal and a local clock pulse generator and logical control signals for the clock are derived.
Abstract: A circuit for detecting timing errors between a binary signal and a local clock pulse generator is described. Three binary samples are compared and logical control signals for the clock are derived.
328 citations
•
[...]
TL;DR: 1. The Petersen graph 2. The four colour problem 3. Snarks 4. Factors 5. Beyond the four colour theorem 6. Cages 7. Hypohamiltonian graphs 8. Symmetry 9. Petersen graph in diversity Index.
Abstract: The Petersen graph occupies an important position in the development of several areas of modern graph theory because it often appears as a counter-example to important conjectures. In this account, the authors examine those areas, using the prominent role of the Petersen graph as a unifying feature. Topics covered include: vertex and edge colourability (including snarks), factors, flows, projective geometry, cages, hypohamiltonian graphs, and 'symmetry' properties such as distance transitivity. The final chapter contains a pot-pourri of other topics in which the Petersen graph has played its part. Undergraduate students will be able to profit from reading this book as the prerequisites are few; thus it could be used for a second course in graph theory. On the other hand, the authors have also included a number of unsolved problems as well as topics of recent study. Thus it will also be useful as a reference for graph theorists.
328 citations
••
TL;DR: Demented and non-demented PD patients differ quantitatively but not qualitatively in terms of the relative prominence of deficits on tests of phonemic and semantic fluency, but patients with dementia of the Alzheimer's type and dementedPD patients can be differentiated from one another by the relative magnitude of deficits upon these two measures.
Abstract: A meta-analysis of 68 studies with a total of 4644 participants was conducted to investigate the sensitivity of tests of verbal fluency to the presence of Parkinson's disease (PD) relative to healthy controls. Both phonemic and semantic fluency were moderately impaired but neither deficit qualified as a differential deficit relative to verbal intelligence or psychomotor speed. However, PD patients were significantly more impaired on semantic relative to phonemic fluency (rs =.37 vs.33, respectively), and confrontation naming, a test of semantic memory that imposes only minimal demands upon cognitive speed and effortful retrieval, was associated with a deficit that was of a comparable magnitude to the deficits upon each of these types of fluency. Thus, the disorder appears to be associated with particular problems with semantic memory. Tests that impose heavy demands upon switching may also be disproportionately affected. Demented and non-demented PD patients differ quantitatively but not qualitatively in terms of the relative prominence of deficits on tests of phonemic and semantic fluency. However, patients with dementia of the Alzheimer's type and demented PD patients can be differentiated from one another by the relative magnitude of deficits upon these two measures.
328 citations
Authors
Showing all 21424 results
Name | H-index | Papers | Citations |
---|---|---|---|
Paul M. Thompson | 183 | 2271 | 146736 |
Feng Zhang | 172 | 1278 | 181865 |
Ian J. Deary | 166 | 1795 | 114161 |
Peter A. R. Ade | 162 | 1387 | 138051 |
David W. Johnson | 160 | 2714 | 140778 |
Pete Smith | 156 | 2464 | 138819 |
Naveed Sattar | 155 | 1326 | 116368 |
John R. Hodges | 149 | 812 | 82709 |
Ruth J. F. Loos | 142 | 647 | 92485 |
Alan J. Silman | 141 | 708 | 92864 |
Michael J. Keating | 140 | 1169 | 76353 |
David Price | 138 | 1687 | 93535 |
John D. Scott | 135 | 625 | 83878 |
Aarno Palotie | 129 | 711 | 89975 |
Rajat Gupta | 126 | 1240 | 72881 |