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Institution

University of Aberdeen

EducationAberdeen, United Kingdom
About: University of Aberdeen is a education organization based out in Aberdeen, United Kingdom. It is known for research contribution in the topics: Population & Health care. The organization has 21174 authors who have published 49962 publications receiving 2105479 citations. The organization is also known as: Aberdeen University.


Papers
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Journal ArticleDOI
TL;DR: The sordarins represent a novel class of agents that inhibit fungal protein synthesis, and three are echinocandins, which inhibit synthesis of fungal cell wall polysaccharides--a new mode of action.

1,039 citations

Journal ArticleDOI
TL;DR: The Blueprint PD‐L1 IHC Assay Comparison Project revealed that three of the four assays were closely aligned on tumor cell staining whereas the fourth showed consistently fewer tumor cells stained, indicating that interchanging assays and cutoffs would lead to “misclassification” of PD‐ L1 status for some patients.

1,034 citations

Journal ArticleDOI
TL;DR: A combination of stable isotope and acetylene (0.01% v/v) inhibition techniques were used for the first time to determine N2O production during denitrification, autotrophic nitrification and heterotrophic Nitrification in a silt loam soil at contrasting (20-70%) water-filled pore space (WFPS) as mentioned in this paper.
Abstract: A combination of stable isotope and acetylene (0.01% v/v) inhibition techniques were used for the first time to determine N2O production during denitrification, autotrophic nitrification and heterotrophic nitrification in a fertilised (200 kg N ha−1) silt loam soil at contrasting (20–70%) water-filled pore space (WFPS). 15N-N2O emissions from 14NH415NO3 replicates were attributed to denitrification and 15N-N2O from 15NH415NO3 minus that from 14NH415NO3 replicates was attributed to nitrification and heterotrophic nitrification in the presence of acetylene, as there was no dissimilatory nitrate reduction to ammonium or immobilisation and remineralisation of 15N-NO3−. All of the N2O emitted at 70% WFPS (31.6 mg N2O-N m−2 over 24 days; 1.12 μg N2O-N g dry soil−1; 0.16% of N applied) was produced during denitrification, but at 35–60% WFPS nitrification was the main process producing N2O, accounting for 81% of 15N-N2O emitted at 60% WFPS, and 7.9 μg 15N-N2O m−2 (0.28 ng 15N-N2O g dry soil−1) was estimated to be emitted over 7 days during heterotrophic nitrification in the 50% WFPS treatment and accounted for 20% of 15N-N2O from this treatment. Denitrification was the predominant N2O-producing process at 20% WFPS (2.6 μg 15N-N2O m−2 over 7 days; 0.09 ng 15N-N2O g dry soil−1; 85% of 15N-N2O from this treatment) and may have been due to the occurrence of aerobic denitrification at this WFPS. Our results demonstrate the usefulness of a combined stable isotope and acetylene approach to quantify N2O emissions from different processes and to show that several processes may contribute to N2O emission from agricultural soils depending on soil WFPS.

1,031 citations

Journal ArticleDOI
TL;DR: The results show that interventions to improve antibiotic prescribing to hospital inpatients are successful, and can reduce antimicrobial resistance or hospital acquired infections.
Abstract: This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: Aim: To systematically review the literature to identify interventions that alone, or in combination, are effective in improving antibiotic prescribing to hospital inpatients. Research questions: What is the evidence that exposure of hospital inpatients to antibiotics can be reduced safely, without compromising clinical outcomes? What is the evidence that changing the antibiotic choice, dose or route can be achieved without compromising clinical outcomes? Are interventions that include goal setting, feedback and action planning more effective than interventions that only include one or two of these components? Do interventions that include behaviour change techniques to enhance capability have greater initial effect (Michie 2011)? Do interventions that include behaviour change techniques to enhance capability have more sustained effectiveness (Michie 2011)? What is the relationship between change in antibiotic use or choice and microbial outcomes? Withdrawal from publication: this protocol was written with the express purpose of updating the methodology for the review, and has now been superseded by the updated review (Davey 2017).

1,030 citations

Journal ArticleDOI
TL;DR: Evidence from neuroimaging, psychophysiological studies, and related fields are reviewed to argue for the development of a second-person neuroscience, which will help neuroscience to really “go social” and may also be relevant for the understanding of psychiatric disorders construed as disorders of social cognition.
Abstract: In spite of the remarkable progress made in the burgeoning field of social neuroscience, the neural mechanisms that underlie social encounters are only beginning to be studied and could-paradoxically-be seen as representing the "dark matter" of social neuroscience. Recent conceptual and empirical developments consistently indicate the need for investigations that allow the study of real-time social encounters in a truly interactive manner. This suggestion is based on the premise that social cognition is fundamentally different when we are in interaction with others rather than merely observing them. In this article, we outline the theoretical conception of a second-person approach to other minds and review evidence from neuroimaging, psychophysiological studies, and related fields to argue for the development of a second-person neuroscience, which will help neuroscience to really "go social"; this may also be relevant for our understanding of psychiatric disorders construed as disorders of social cognition.

1,022 citations


Authors

Showing all 21424 results

NameH-indexPapersCitations
Paul M. Thompson1832271146736
Feng Zhang1721278181865
Ian J. Deary1661795114161
Peter A. R. Ade1621387138051
David W. Johnson1602714140778
Pete Smith1562464138819
Naveed Sattar1551326116368
John R. Hodges14981282709
Ruth J. F. Loos14264792485
Alan J. Silman14170892864
Michael J. Keating140116976353
David Price138168793535
John D. Scott13562583878
Aarno Palotie12971189975
Rajat Gupta126124072881
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023141
2022362
20212,195
20202,118
20191,846
20181,894