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Institution

University of Aberdeen

EducationAberdeen, United Kingdom
About: University of Aberdeen is a education organization based out in Aberdeen, United Kingdom. It is known for research contribution in the topics: Population & Health care. The organization has 21174 authors who have published 49962 publications receiving 2105479 citations. The organization is also known as: Aberdeen University.


Papers
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Journal ArticleDOI
TL;DR: In this article, the authors estimated that between 1995 and 2005, the livestock sector was responsible for greenhouse gas emissions of 5.6-7.5GtCO(2)e yr(-1).
Abstract: The livestock sector supports about 1.3 billion producers and retailers, and contributes 40-50% of agricultural GDP. We estimated that between 1995 and 2005, the livestock sector was responsible for greenhouse gas emissions of 5.6-7.5GtCO(2)e yr(-1). Livestock accounts for up to half of the technical mitigation potential of the agriculture, forestry and land-use sectors, through management options that sustainably intensify livestock production, promote carbon sequestration in rangelands and reduce emissions from manures, and through reductions in the demand for livestock products. The economic potential of these management alternatives is less than 10% of what is technically possible because of adoption constraints, costs and numerous trade-offs. The mitigation potential of reductions in livestock product consumption is large, but their economic potential is unknown at present. More research and investment are needed to increase the affordability and adoption of mitigation practices, to moderate consumption of livestock products where appropriate, and to avoid negative impacts on livelihoods, economic activities and the environment.

570 citations

Journal ArticleDOI
Douglas M. Ruderfer1, Stephan Ripke2, Stephan Ripke3, Stephan Ripke4  +628 moreInstitutions (156)
14 Jun 2018-Cell
TL;DR: For the first time, specific loci that distinguish between BD and SCZ are discovered and polygenic components underlying multiple symptom dimensions are identified that point to the utility of genetics to inform symptomology and potential treatment.

569 citations

Journal ArticleDOI
TL;DR: The EORTC QLQ-C30 has become the most widely used questionnaire in Europe for cancer patients, and is extensively used around the world as mentioned in this paper. But it is not suitable for all patients.

569 citations

Journal ArticleDOI
TL;DR: In this article, a disordered layer structure of Calcium silicate hydrate gel is presented, in which most of the layers are structurally imperfect ones of jennite (Ca9Si6O32H22), and others are similarly related to 1.4-nm tobermorite, both structures being modified by omission of many of their silicate tetrahedra.
Abstract: Calcium silicate hydrate gel is a very poorly crystalline material that is the main product of reaction of portland cement with water. Evidence is presented for a disordered layer structure, in which most of the layers are structurally imperfect ones of jennite (Ca9Si6O32H22), and others are similarly related to 1.4-nm tobermorite (Ca5Si6O26H18), both structures being modified by omission of many of their silicate tetrahedra. The evidence comprises conditions of formation, silicate anion type, Ca/Si ratio, H2O/Ca ratios and densities for various drying conditions, thermogravimetric curve, X-ray powder and selected-area electron diffraction patterns, and results of analytical electron microfcopy.

569 citations

Journal ArticleDOI
Jason Z. Liu1, Federica Tozzi2, Dawn M. Waterworth2, Sreekumar G. Pillai2, Pierandrea Muglia2, Lefkos T. Middleton3, Wade H. Berrettini4, Christopher W. Knouff2, Xin Yuan2, Gérard Waeber5, Peter Vollenweider5, Martin Preisig5, Nicholas J. Wareham6, Jing Hua Zhao6, Ruth J. F. Loos6, Ins Barroso7, Kay-Tee Khaw8, Scott M. Grundy, Philip J. Barter9, Robert W. Mahley10, Antero Kesäniemi11, Ruth McPherson12, John B. Vincent13, John Strauss13, James L. Kennedy13, Anne Farmer14, Peter McGuffin14, Richard O. Day15, Keith Matthews15, Per Bakke16, Amund Gulsvik16, Susanne Lucae17, Marcus Ising17, T. Brueckl17, S. Horstmann17, H.-Erich Wichmann18, Rajesh Rawal, Norbert Dahmen19, Claudia Lamina20, Ozren Polasek21, Lina Zgaga22, Jennifer E. Huffman22, Susan Campbell22, Jaspal S. Kooner3, John C. Chambers3, Mary Susan Burnett23, Joseph M. Devaney23, Augusto D. Pichard23, Kenneth M. Kent23, Lowell F. Satler23, Joseph M. Lindsay23, Ron Waksman23, Stephen E. Epstein23, James F. Wilson22, Sarah H. Wild22, Harry Campbell22, Veronique Vitart22, Muredach P. Reilly4, Mingyao Li4, Liming Qu4, Robert L. Wilensky4, William H. Matthai4, Hakon Hakonarson4, Daniel J. Rader4, Andre Franke24, Michael Wittig24, Arne Schäfer24, Manuela Uda25, Antonio Terracciano26, Xiangjun Xiao27, Fabio Busonero25, Paul Scheet27, David Schlessinger26, David St Clair28, Dan Rujescu18, Gonçalo R. Abecasis29, Hans J. Grabe30, Alexander Teumer30, Henry Völzke30, Astrid Petersmann30, Ulrich John30, Igor Rudan31, Igor Rudan22, Caroline Hayward22, Alan F. Wright22, Ivana Kolcic21, Benjamin J. Wright32, John R. Thompson32, Anthony J. Balmforth33, Alistair S. Hall33, Nilesh J. Samani32, Carl A. Anderson7, Tariq Ahmad, Christopher G. Mathew34, Miles Parkes, Jack Satsangi22, Mark J. Caulfield35, Patricia B. Munroe35, Martin Farrall1, Anna F. Dominiczak36, Jane Worthington, Wendy Thomson, Steve Eyre, Anne Barton, Vincent Mooser2, Clyde Francks1, Clyde Francks2, Jonathan Marchini1 
TL;DR: The Oxford-GlaxoSmithKline study (Ox-GSK) as discussed by the authors performed a genome-wide meta-analysis of SNP association with smoking-related behavioral traits and found an effect on smoking quantity at a locus on 15q25 (P = 9.45 x 10(-19) that includes CHRNA5, CHRNA3 and CHRNB4.
Abstract: Smoking is a leading global cause of disease and mortality. We established the Oxford-GlaxoSmithKline study (Ox-GSK) to perform a genome-wide meta-analysis of SNP association with smoking-related behavioral traits. Our final data set included 41,150 individuals drawn from 20 disease, population and control cohorts. Our analysis confirmed an effect on smoking quantity at a locus on 15q25 (P = 9.45 x 10(-19)) that includes CHRNA5, CHRNA3 and CHRNB4, three genes encoding neuronal nicotinic acetylcholine receptor subunits. We used data from the 1000 Genomes project to investigate the region using imputation, which allowed for analysis of virtually all common SNPs in the region and offered a fivefold increase in marker density over HapMap2 (ref. 2) as an imputation reference panel. Our fine-mapping approach identified a SNP showing the highest significance, rs55853698, located within the promoter region of CHRNA5. Conditional analysis also identified a secondary locus (rs6495308) in CHRNA3.

568 citations


Authors

Showing all 21424 results

NameH-indexPapersCitations
Paul M. Thompson1832271146736
Feng Zhang1721278181865
Ian J. Deary1661795114161
Peter A. R. Ade1621387138051
David W. Johnson1602714140778
Pete Smith1562464138819
Naveed Sattar1551326116368
John R. Hodges14981282709
Ruth J. F. Loos14264792485
Alan J. Silman14170892864
Michael J. Keating140116976353
David Price138168793535
John D. Scott13562583878
Aarno Palotie12971189975
Rajat Gupta126124072881
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023141
2022362
20212,195
20202,118
20191,846
20181,894