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Institution

University of Adelaide

EducationAdelaide, South Australia, Australia
About: University of Adelaide is a education organization based out in Adelaide, South Australia, Australia. It is known for research contribution in the topics: Population & Poison control. The organization has 27251 authors who have published 79167 publications receiving 2671128 citations. The organization is also known as: The University of Adelaide & Adelaide University.


Papers
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Journal ArticleDOI
TL;DR: A potassium iron (II) hexacyanoferrate nanocube cathode material is reported, which operates with an aqueous electrolyte to deliver exceptionally high capacities (up to 120 mA h g-1 ).
Abstract: A potassium iron (II) hexacyanoferrate nanocube cathode material is reported, which operates with an aqueous electrolyte to deliver exceptionally high capacities (up to 120 mA h g(-1)) The cathode material exhibits excellent structural integrity, leading to fast kinetics and highly reversible properties All of the battery materials are safe, inexpensive, and provide superior high-rate, long-cycle-life electrochemical performance

456 citations

Journal ArticleDOI
TL;DR: Wang et al. as mentioned in this paper proposed a method to solve the problem of high computational complexity in the context of Chemical and Biomedical Engineering at Nanyang Technological University in Singapore.
Abstract: Dr. S. Q. Wang, L. Xia, Prof. H. H. Wang School of Chemistry and Chemical Engineering South China University of Technology Guangzhou 510640 , China E-mail: hhwang@scut.edu.cn Dr. L. Zhang, Prof. H. H. Wang School of Chemical Engineering The University of Adelaide SA 5005 , Australia L. Yu, Prof. X. W. Lou School of Chemical and Biomedical Engineering Nanyang Technological University 62 Nanyang Drive Singapore 637459 , Singapore E-mail: xwlou@ntu.edu.sg

456 citations

Journal ArticleDOI
04 Jul 2014-Science
TL;DR: It is reported that unmitigated ER stress promoted apoptosis through cell-autonomous, UPR-controlled activation of death receptor 5 (DR5), which integrates opposing UPR signals to couple ER stress and apoptotic cell fate.
Abstract: Protein folding by the endoplasmic reticulum (ER) is physiologically critical; its disruption causes ER stress and augments disease. ER stress activates the unfolded protein response (UPR) to restore homeostasis. If stress persists, the UPR induces apoptotic cell death, but the mechanisms remain elusive. Here, we report that unmitigated ER stress promoted apoptosis through cell-autonomous, UPR-controlled activation of death receptor 5 (DR5). ER stressors induced DR5 transcription via the UPR mediator CHOP; however, the UPR sensor IRE1α transiently catalyzed DR5 mRNA decay, which allowed time for adaptation. Persistent ER stress built up intracellular DR5 protein, driving ligand-independent DR5 activation and apoptosis engagement via caspase-8. Thus, DR5 integrates opposing UPR signals to couple ER stress and apoptotic cell fate.

456 citations

Journal ArticleDOI
TL;DR: The first whole-genome sequence of a basal lepidopteran species, Plutella xylostella, is reported, which contains 18,071 protein-coding and 1,412 unique genes with an expansion of gene families associated with perception and the detoxification of plant defense compounds.
Abstract: How an insect evolves to become a successful herbivore is of profound biological and practical importance. Herbivores are often adapted to feed on a specific group of evolutionarily and biochemically related host plants, but the genetic and molecular bases for adaptation to plant defense compounds remain poorly understood. We report the first whole-genome sequence of a basal lepidopteran species, Plutella xylostella, which contains 18,071 protein-coding and 1,412 unique genes with an expansion of gene families associated with perception and the detoxification of plant defense compounds. A recent expansion of retrotransposons near detoxification-related genes and a wider system used in the metabolism of plant defense compounds are shown to also be involved in the development of insecticide resistance. This work shows the genetic and molecular bases for the evolutionary success of this worldwide herbivore and offers wider insights into insect adaptation to plant feeding, as well as opening avenues for more sustainable pest management.

455 citations

Journal ArticleDOI
TL;DR: Although global drivers could be affecting kelp forests at multiple scales, local stressors and regional variation in the effects of these drivers dominate kelp dynamics, in contrast to many other marine and terrestrial foundation species.
Abstract: Kelp forests (Order Laminariales) form key biogenic habitats in coastal regions of temperate and Arctic seas worldwide, providing ecosystem services valued in the range of billions of dollars annually. Although local evidence suggests that kelp forests are increasingly threatened by a variety of stressors, no comprehensive global analysis of change in kelp abundances currently exists. Here, we build and analyze a global database of kelp time series spanning the past half-century to assess regional and global trends in kelp abundances. We detected a high degree of geographic variation in trends, with regional variability in the direction and magnitude of change far exceeding a small global average decline (instantaneous rate of change = −0.018 y−1). Our analysis identified declines in 38% of ecoregions for which there are data (−0.015 to −0.18 y−1), increases in 27% of ecoregions (0.015 to 0.11 y−1), and no detectable change in 35% of ecoregions. These spatially variable trajectories reflected regional differences in the drivers of change, uncertainty in some regions owing to poor spatial and temporal data coverage, and the dynamic nature of kelp populations. We conclude that although global drivers could be affecting kelp forests at multiple scales, local stressors and regional variation in the effects of these drivers dominate kelp dynamics, in contrast to many other marine and terrestrial foundation species.

455 citations


Authors

Showing all 27579 results

NameH-indexPapersCitations
Martin White1962038232387
Nicholas G. Martin1921770161952
David W. Johnson1602714140778
Nicholas J. Talley158157190197
Mark E. Cooper1581463124887
Xiang Zhang1541733117576
John E. Morley154137797021
Howard I. Scher151944101737
Christopher M. Dobson1501008105475
A. Artamonov1501858119791
Timothy P. Hughes14583191357
Christopher Hill1441562128098
Shi-Zhang Qiao14252380888
Paul Jackson141137293464
H. A. Neal1411903115480
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023127
2022597
20215,500
20205,342
20194,803
20184,443