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Institution

University of Alabama

EducationTuscaloosa, Alabama, United States
About: University of Alabama is a education organization based out in Tuscaloosa, Alabama, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 27323 authors who have published 48609 publications receiving 1565337 citations. The organization is also known as: Alabama & Bama.


Papers
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Journal ArticleDOI
TL;DR: The progress of the work on device design, material improvement, wafer processing, integration with CMOS, and testing for a demonstration STT-RAM test chip are reported, and projections based on modeling of the future characteristics of STt-RAM are projected.
Abstract: Spin-transfer torque random access memory (STT-RAM) is a potentially revolutionary universal memory technology that combines the capacity and cost benefits of DRAM, the fast read and write performance of SRAM, the non-volatility of Flash, and essentially unlimited endurance. In order to realize a small cell size, high speed and achieve a fully functional STT-RAM chip, the MgO-barrier magnetic tunnel junctions (MTJ) used as the core storage and readout element must meet a set of performance requirements on switching current density, voltage, magneto-resistance ratio (MR), resistance-area product (RA), thermal stability factor (?) , switching current distribution, read resistance distribution and reliability. In this paper, we report the progress of our work on device design, material improvement, wafer processing, integration with CMOS, and testing for a demonstration STT-RAM test chip, and projections based on modeling of the future characteristics of STT-RAM.

401 citations

Journal ArticleDOI
TL;DR: Investigating the effect of an individual's political skill on the relationships between 5 different impression management tactics and supervisor evaluations of performance showed that individuals who used high levels of any of the tactics and who were politically skilled achieved more desirable supervisor ratings.
Abstract: In this study, the authors investigated the effect of an individual's political skill on the relationships between 5 different impression management tactics (intimidation, exemplification, ingratiation, self-promotion, and supplication) and supervisor evaluations of performance. To test these relationships, the authors used a matched sample of 173 supervisor-subordinate dyads who worked full time in a state agency. Findings showed that individuals who used high levels of any of the tactics and who were politically skilled achieved more desirable supervisor ratings than did those who used the tactics but were not politically skilled. Opposite results were found when impression management usage was low. That is, individuals who were not politically skilled created a more desirable image in their supervisors' eyes than did their politically skilled counterparts when they did not use these tactics. Practical and research implications for the findings as well as directions for future research are offered.

400 citations

Journal ArticleDOI
TL;DR: The chemotherapy was satisfactorily tolerated and did not affect the ability to deliver the subsequent radiotherapy, and implications for future clinical trials are discussed.
Abstract: To test the efficacy of sequential chemotherapy as an adjuvant to surgery and postoperative radiotherapy for patients with locally-advanced but operable squamous cell cancers of the head and neck region, a randomized clinical trial was conducted under the auspices of the Head and Neck Intergroup (Radiation Therapy Oncology Group, Southwest Oncology Group, Eastern Oncology Group, Cancer and Leukemia Group B, Northern California Oncology Group, and Southeast Group). Eligible patients had completely resected tumors of the oral cavity, oropharynx, hypopharynx, or larynx. They were then randomized to receive either three cycles of cis-platinum and 5-FU chemotherapy followed by postoperative radiotherapy (CT/RT) or postoperative radiotherapy alone (RT). Patients were categorized as having either "low-risk" or "high-risk" treatment volumes depending on whether the surgical margin was greater than or equal to 5 mm, there was extracapsular nodal extension, and/or there was carcinoma-in-situ at the surgical margins. Radiation doses of 50-54 Gy were given to "low-risk" volumes and 60 Gy were given to "high-risk" volumes. A total of 442 analyzable patients were entered into this study with the mean-time-at-risk being 45.7 months at the time of the present analysis. The 4-year actuarial survival rate was 44% on the RT arm and 48% on the CT/RT arm (p = n.s.). Disease-free survival at 4 years was 38% on the RT arm compared to 46% on the CT/RT arm (p = n.s.). At 4 years the local/regional failure rate was 29% vs. 26% for the RT and CT/RT arms, respectively (p = n.s.). The incidence of first failure in the neck nodes was 10% on the RT arm compared to 5% on the CT/RT arm (p = 0.03 without adjusting for multiple testing) and the overall incidence of distant metastases was 23% on the RT arm compared to 15% on the CT/RT arm (p = 0.03). Treatment related toxicity is discussed in detail, but, in general, the chemotherapy was satisfactorily tolerated and did not affect the ability to deliver the subsequent radiotherapy. Implications for future clinical trials are discussed.

400 citations

Journal ArticleDOI
Martin H. Steinberg1, William F. McCarthy, Oswaldo Castro2, Samir K. Ballas3, F. Danny Armstrong4, Wally R. Smith5, Kenneth I. Ataga6, Paul Swerdlow7, Abdullah Kutlar8, Laura DeCastro9, Myron A. Waclawiw10, Eugene P. Orringer6, Susan Jones6, D. Strayhorn6, Wendell F. Rosse9, George Phillips9, D. Peace9, A. Johnson-Telfair9, Lisa Daitch8, Paul F. Milner8, A. Tracy8, S. Valdez3, G. E. Allen3, J. Moshang3, B. Scott3, Carolyn Bigelow11, A. Anderson11, V. Sabahi11, T. Harrington4, W. Labrousse4, Charles H. Pegelow4, D. Temple4, E. Case4, R. Harrell4, S. Childerie4, Stephen H. Embury12, B. Schmidt12, D. Davies12, Yogen Saunthararajah13, Mabel Koshy13, N. Talischy-Zahed13, L. Dorn13, G. Pendarvis13, M. McGee13, Margaret Telfer, A. Davis, O. C. Onyekwere2, C. Nwokolo2, Helga Finke2, Elliott Perlin2, J. Siteman2, M. Bryan14, T. Saunders14, Y. Barber14, P. Gascon14, P. Di Paolo14, S. Gargiulo14, James R. Eckman15, E. Carter-Randall15, J. H. Bailey15, A. Platt15, L. Waller15, G. Ramirez16, V. Knors16, S. Hernandez16, E. M. Rodriguez16, E. Wilkes16, Elliott Vichinsky17, Ward Hagar17, C. Hoehner17, E. Hackney-Stevens17, S. Claster17, A. Earles17, K. Kleman17, K. McLaughlin17, L. White5, B. Maddox5, L. Usry5, A. Brenner5, K. Williams5, R. O'Brien5, K. Genther5, Susan B. Shurin18, Brian W. Berman18, K. Chiarucci18, L. Keverline18, Nancy F. Olivieri19, J. Chow19, M. Hui19, D. Shaw19, N. Lewis19, Maureen Okam20, Elyse Mandell20, A. Palmer20, Kenneth Bridges20, B. Tynan20, C. Winograd20, Rita Bellevue21, Harvey Dosik21, M. Sheikhai21, P. Ryans21, H. Souffrant21, Brian Adler22, L. Eskridge22, Josef T. Prchal22, J. Braddock22, T. McArdle22, Timothy M. Carlos23, A. Roundtree-Schmotzer23, D. Gardner23 
TL;DR: It is suggested that long‐term use of hydroxyurea is safe and might decrease mortality, while no longer the product of a randomized study because of the ethical concerns of withholding an efficacious treatment.
Abstract: A randomized, controlled clinical trial established the efficacy and safety of short-term use of hydroxyurea in adult sickle cell anemia. To examine the risks and benefits of long-term hydroxyurea usage, patients in this trial were followed for 17.5 years during which they could start or stop hydroxyurea. The purpose of this follow-up was to search for adverse outcomes and estimate mortality. For each outcome and for mortality, exact 95% confidence intervals were calculated, or tests were conducted at alpha = 0.05 level (P-value <0.05 for statistical significance). Although the death rate in the overall study cohort was high (43.1%; 4.4 per 100 person-years), mortality was reduced in individuals with long-term exposure to hydroxyurea. Survival curves demonstrated a significant reduction in deaths with long-term exposure. Twenty-four percent of deaths were due to pulmonary complications; 87.1% occurred in patients who never took hydroxyurea or took it for <5 years. Stroke, organ dysfunction, infection, and malignancy were similar in all groups. Our results, while no longer the product of a randomized study because of the ethical concerns of withholding an efficacious treatment, suggest that long-term use of hydroxyurea is safe and might decrease mortality.

399 citations

Journal ArticleDOI
TL;DR: In this article, the authors developed personal health monitors based on a wireless body area network (BAN) of intelligent sensors, which were integrated into a distributed wireless system for synchronized monitoring a group of subjects.
Abstract: We are developing personal health monitors based on a wireless body area network (BAN) of intelligent sensors. Individual monitors will be integrated into a distributed wireless system for synchronized monitoring of a group of subjects. This system could be used during the selection process and as part of a psychophysiological evaluation of military members undergoing intense training. We use measures of heart-rate variability to quantify stress level prior to and during training as well as to predict stress resistance. This task requires reliable, high-precision instrumentation and synchronized measurements from a group of individuals over prolonged periods (days of training).

399 citations


Authors

Showing all 27508 results

NameH-indexPapersCitations
Jasvinder A. Singh1762382223370
Hongfang Liu1662356156290
Ian J. Deary1661795114161
Yongsun Kim1562588145619
Dong-Chul Son138137098686
Simon C. Watkins13595068358
Kenichi Hatakeyama1341731102438
Conor Henderson133138788725
Peter R Hobson133159094257
Tulika Bose132128588895
Helen F Heath132118589466
James Rohlf131121589436
Panos A Razis130128790704
David B. Allison12983669697
Eduardo Marbán12957949586
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202372
2022357
20212,703
20202,759
20192,602
20182,411