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Institution

University of Alberta

EducationEdmonton, Alberta, Canada
About: University of Alberta is a education organization based out in Edmonton, Alberta, Canada. It is known for research contribution in the topics: Population & Health care. The organization has 65403 authors who have published 154847 publications receiving 5358338 citations. The organization is also known as: Ualberta & UAlberta.


Papers
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Journal ArticleDOI
TL;DR: Accumulation of 5′-AMP during ischemia results in an activation of AMP-activated protein kinase, which phosphorylates and inactivates ACC during reperfusion, and the subsequent decrease in malonyl-CoA levels will result in accelerated fatty acid oxidation rates during reperFusion of ischemic hearts.

606 citations

Posted Content
TL;DR: In this article, the authors investigate how competing logics facilitate resistance to institutional change, focusing on banking professionals' resistance to large, national banks' acquisitions of smaller, local banks, and argue that these efforts to introduce a banking logic emphasizing efficiencies of geographic diversification triggered new forms of professional entrepreneurialism intended to preserve a community logic of banking.
Abstract: We investigate how competing logics facilitate resistance to institutional change, focusing on banking professionals' resistance to large, national banks' acquisitions of smaller, local banks. Acquisitions led to new bank foundings, particularly when out-of-town banks were the acquirers and a community's local population of bank professionals was large. We argue that the national banks' efforts to introduce a banking logic emphasizing efficiencies of geographic diversification triggered new forms of professional entrepreneurialism intended to preserve a community logic of banking. Contributions to a synthesis of ecological and institutional perspectives and to research on entrepreneurship and resistance to institutional change are discussed.

606 citations

Journal ArticleDOI
01 Sep 1999-Neuron
TL;DR: It is demonstrated that individual neurons within the paraventricular nucleus of the hypothalamus (PVH) are capable of detection and integration of orexigenic and anorexigenic signals and that melanocortin administration within the PVH regulates both feeding behavior and energy expenditure.

605 citations

Journal ArticleDOI
13 Mar 2014-Nature
TL;DR: X-ray diffraction, Raman and infrared spectroscopic data are reported that provide the first evidence for the terrestrial occurrence of any higher-pressure polymorph of olivine: ringwoodite is included in a diamond from Juína, Brazil, providing direct evidence that, at least locally, the transition zone is hydrous.
Abstract: X-ray diffraction, Raman and infrared spectroscopic evidence for the inclusion of water-rich ringwoodite in diamond from Juina, Brazil, indicates that, at least locally, the Earth’s transition zone is hydrous to about 1 weight per cent. It is not clear just how much water resides within the solid Earth, and where it is to be found, with many indirect measurements yielding conflicting results. Here Graham Pearson and co-authors present evidence from a diamond inclusion from Juina, Brazil, for the first known terrestrial occurrence of ringwoodite — a high-pressure polymorph of olivine first identified in meteorites and thought to be a major constituent of the Earth's mantle transition zone. The water-rich nature of this inclusion provides direct evidence that, at least locally, the transition zone is hydrous, to about 1 weight per cent. The ultimate origin of water in the Earth’s hydrosphere is in the deep Earth—the mantle. Theory1 and experiments2,3,4 have shown that although the water storage capacity of olivine-dominated shallow mantle is limited, the Earth’s transition zone, at depths between 410 and 660 kilometres, could be a major repository for water, owing to the ability of the higher-pressure polymorphs of olivine—wadsleyite and ringwoodite—to host enough water to comprise up to around 2.5 per cent of their weight. A hydrous transition zone may have a key role in terrestrial magmatism and plate tectonics5,6,7, yet despite experimental demonstration of the water-bearing capacity of these phases, geophysical probes such as electrical conductivity have provided conflicting results8,9,10, and the issue of whether the transition zone contains abundant water remains highly controversial11. Here we report X-ray diffraction, Raman and infrared spectroscopic data that provide, to our knowledge, the first evidence for the terrestrial occurrence of any higher-pressure polymorph of olivine: we find ringwoodite included in a diamond from Juina, Brazil. The water-rich nature of this inclusion, indicated by infrared absorption, along with the preservation of the ringwoodite, is direct evidence that, at least locally, the transition zone is hydrous, to about 1 weight per cent. The finding also indicates that some kimberlites must have their primary sources in this deep mantle region.

605 citations

Proceedings ArticleDOI
14 Jun 2009
TL;DR: In this paper, the authors introduced two new related algorithms with better convergence rates: linear TD with gradient correction (TDC) and TDC with zero term update rule, which can be used for off-policy TD.
Abstract: Sutton, Szepesvari and Maei (2009) recently introduced the first temporal-difference learning algorithm compatible with both linear function approximation and off-policy training, and whose complexity scales only linearly in the size of the function approximator. Although their gradient temporal difference (GTD) algorithm converges reliably, it can be very slow compared to conventional linear TD (on on-policy problems where TD is convergent), calling into question its practical utility. In this paper we introduce two new related algorithms with better convergence rates. The first algorithm, GTD2, is derived and proved convergent just as GTD was, but uses a different objective function and converges significantly faster (but still not as fast as conventional TD). The second new algorithm, linear TD with gradient correction, or TDC, uses the same update rule as conventional TD except for an additional term which is initially zero. In our experiments on small test problems and in a Computer Go application with a million features, the learning rate of this algorithm was comparable to that of conventional TD. This algorithm appears to extend linear TD to off-policy learning with no penalty in performance while only doubling computational requirements.

605 citations


Authors

Showing all 66027 results

NameH-indexPapersCitations
Salim Yusuf2311439252912
Yi Chen2174342293080
Robert M. Califf1961561167961
Douglas R. Green182661145944
Russel J. Reiter1691646121010
Jiawei Han1681233143427
Jaakko Kaprio1631532126320
Tobin J. Marks1591621111604
Josef M. Penninger154700107295
Subir Sarkar1491542144614
Gerald M. Edelman14754569091
Rinaldo Bellomo1471714120052
P. Sinervo138151699215
David A. Jackson136109568352
Andreas Warburton135157897496
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20241
2023234
20221,084
20219,315
20208,831
20198,177