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Institution

University of Alberta

EducationEdmonton, Alberta, Canada
About: University of Alberta is a education organization based out in Edmonton, Alberta, Canada. It is known for research contribution in the topics: Population & Health care. The organization has 65403 authors who have published 154847 publications receiving 5358338 citations. The organization is also known as: Ualberta & UAlberta.


Papers
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Journal ArticleDOI
Georges Aad1, Brad Abbott2, Jalal Abdallah3, S. Abdel Khalek  +3081 moreInstitutions (197)
TL;DR: A combined search for the Standard Model Higgs boson with the ATLAS experiment at the LHC using datasets corresponding to integrated luminosities from 1.04 fb(-1) to 4.9 fb(1) of pp collisions is described in this paper.

572 citations

Journal ArticleDOI
TL;DR: In this article, the authors examined the source of normal arc magmas and concluded that they are predominantly derived from partial melting of the metasomatized mantle wedge, with possible minor contributions from subducted sediments.

572 citations

Journal ArticleDOI
01 Dec 2004-Pain
TL;DR: A population‐based cohort study of 1100 randomly selected Saskatchewan adults to determine the annual incidence of neck pain and describe its course found that most individuals with neck pain do not experience complete resolution of their symptoms and disability.
Abstract: Although neck pain is a common source of disability, little is known about its incidence and course. We conducted a population-based cohort study of 1100 randomly selected Saskatchewan adults to determine the annual incidence of neck pain and describe its course. Subjects were initially surveyed by mail in September 1995 and followed-up 6 and 12 months later. The age and gender standardized annual incidence of neck pain is 14.6% (95% confidence interval: 11.3, 17.9). Each year, 0.6% (95% confidence interval: 0.0-1.1) of the population develops disabling neck pain. The annual rate of resolution of neck pain is 36.6% (95% confidence interval: 32.7, 40.5) and another 32.7% (95% confidence interval: 25.5, 39.9) report improvement. Among subjects with prevalent neck pain at baseline, 37.3% (95% confidence interval: 33.4, 41.2) report persistent problems and 9.9% (95% confidence interval: 7.4, 12.5) experience an aggravation during follow-up. Finally, 22.8% (95% confidence interval: 16.4, 29.3) of those with prevalent neck pain at baseline report a recurrent episode. Women are more likely than men to develop neck pain (incidence rate ratio=1.67, 95% confidence interval 1.08-2.60); more likely to suffer from persistent neck problems (incidence rate ratio=1.19, 95% confidence interval 1.03-1.38) and less likely to experience resolution (incidence rate ratio=0.75, 95% confidence interval 0.63-0.88). Neck pain is a disabling condition with a course marked by periods of remission and exacerbation. Contrary to prior belief, most individuals with neck pain do not experience complete resolution of their symptoms and disability.

572 citations

Journal ArticleDOI
TL;DR: The conjecture that most software is also natural - in the sense that it is created by humans at work, with all the attendant constraints and limitations - and thus, like natural language, it is also likely to be repetitive and predictable is investigated.
Abstract: Natural languages like English are rich, complex, and powerful. The highly creative and graceful use of languages like English and Tamil, by masters like Shakespeare and Avvaiyar, can certainly delight and inspire. But in practice, given cognitive constraints and the exigencies of daily life, most human utterances are far simpler and much more repetitive and predictable. In fact, these utterances can be very usefully modeled using modern statistical methods. This fact has led to the phenomenal success of statistical approaches to speech recognition, natural language translation, question-answering, and text mining and comprehension.We begin with the conjecture that most software is also natural, in the sense that it is created by humans at work, with all the attendant constraints and limitations---and thus, like natural language, it is also likely to be repetitive and predictable. We then proceed to ask whether (a) code can be usefully modeled by statistical language models and (b) such models can be leveraged to support software engineers. Using the widely adopted n-gram model, we provide empirical evidence supportive of a positive answer to both these questions. We show that code is also very regular, and, in fact, even more so than natural languages. As an example use of the model, we have developed a simple code completion engine for Java that, despite its simplicity, already improves Eclipse's completion capability. We conclude the paper by laying out a vision for future research in this area.

572 citations

Journal ArticleDOI
13 Jun 2007-JAMA
TL;DR: CRT reduces morbidity and mortality in patients with LV systolic dysfunction, prolonged QRS duration, and New York Heart Association class 3 or 4 symptoms when combined with optimal pharmacotherapy.
Abstract: ContextLeft ventricular (LV) systolic dysfunction causes substantial morbidity and mortality, even with optimal pharmacotherapy. Atrial-synchronized biventricular pacemakers (cardiac resynchronization therapy [CRT]) received US Food and Drug Administration (FDA) approval for use in selected patients with LV systolic dysfunction in 2001.ObjectiveTo summarize the current evidence base for the efficacy, effectiveness, and safety of CRT in patients with LV systolic dysfunction.Evidence AcquisitionA search of multiple electronic databases until November 2006 was supplemented by hand searches of reference lists of included studies and review articles, proceedings booklets from meetings, FDA reports, and contact with primary study authors and device manufacturers. A total of 14 randomized trials (4420 patients) were included for the CRT efficacy review, 106 studies (9209 patients) for the CRT effectiveness review, and 89 studies (9677 patients) reported safety outcomes with implantation of a CRT device.Evidence SynthesisAll patients in the CRT studies had LV systolic dysfunction (mean LV ejection fraction [LVEF] range, 21%-30%), prolonged QRS duration (mean range, 155-209 milliseconds), and 91% had New York Heart Association (NYHA) class 3 or 4 heart failure symptoms despite optimal pharmacotherapy. CRT improved LVEF (weighted mean difference, 3.0%; 95% confidence interval [CI], 0.9%-5.1%), quality of life (weighted mean reduction in Minnesota Living With Heart Failure Questionnaire, 8.0 points; 95% CI, 5.6-10.4 points), and functional status (improvements of ≥1 NYHA class were observed in 59% of CRT recipients in the randomized trials). CRT decreased hospitalizations by 37% (95% CI, 7%-57%), and all-cause mortality decreased by 22% (95% CI, 9%-33%). Implant success rate was 93.0% (95% CI, 92.2%-93.7%) and 0.3% of patients died during implantation (95% CI, 0.1%-0.6%). During a median 11-month follow-up, 6.6% (95% CI, 5.6%-7.4%) of CRT devices exhibited lead problems and 5% (95% CI, 4%-7%) malfunctioned.ConclusionsCRT reduces morbidity and mortality in patients with LV systolic dysfunction, prolonged QRS duration, and NYHA class 3 or 4 symptoms when combined with optimal pharmacotherapy. The incremental benefits of combined CRT plus implantable cardioverter-defibrillator devices vs CRT-alone devices in patients with LV systolic dysfunction remain uncertain.

571 citations


Authors

Showing all 66027 results

NameH-indexPapersCitations
Salim Yusuf2311439252912
Yi Chen2174342293080
Robert M. Califf1961561167961
Douglas R. Green182661145944
Russel J. Reiter1691646121010
Jiawei Han1681233143427
Jaakko Kaprio1631532126320
Tobin J. Marks1591621111604
Josef M. Penninger154700107295
Subir Sarkar1491542144614
Gerald M. Edelman14754569091
Rinaldo Bellomo1471714120052
P. Sinervo138151699215
David A. Jackson136109568352
Andreas Warburton135157897496
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20241
2023234
20221,084
20219,315
20208,831
20198,177