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Institution

University of Alberta

EducationEdmonton, Alberta, Canada
About: University of Alberta is a education organization based out in Edmonton, Alberta, Canada. It is known for research contribution in the topics: Population & Health care. The organization has 65403 authors who have published 154847 publications receiving 5358338 citations. The organization is also known as: Ualberta & UAlberta.


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TL;DR: The authors empirically examined two antecedents of the financial, regulatory, and public dimensions of legitimacy and reputation in a population of US commercial banks and found that isomorphism improves legitimacy, but its effects on reputation depend on the bank's reputation.
Abstract: Organizational legitimacy and organizational reputation have similar antecedents, social construction processes and consequences. Nonetheless, an improved understanding of relationships between legitimacy and reputation requires that differences between the two be specified and clarified. Our examination of past research indicates that legitimacy emphasizes the social acceptance resulting from adherence to social norms and expectations whereas reputation emphasizes comparisons among organizations. We empirically examine two antecedents of the financial, regulatory, and public dimensions of legitimacy and reputation in a population of US commercial banks. We find that isomorphism improves legitimacy, but its effects on reputation depend on the bank's reputation. Moreover, higher financial performance increases reputation, but does not increase the legitimacy of high performing banks.

953 citations

Journal ArticleDOI
TL;DR: In this paper, the authors compared the performance of gyrokinetic and gyrofluid simulations of ion-temperature gradient (ITG)instability and turbulence in tokamak plasmas as well as some tokak plasma thermal transportmodels.
Abstract: The predictions of gyrokinetic and gyrofluid simulations of ion-temperature-gradient(ITG)instability and turbulence in tokamak plasmas as well as some tokamak plasma thermal transportmodels, which have been widely used for predicting the performance of the proposed International Thermonuclear Experimental Reactor (ITER) tokamak [Plasma Physics and Controlled Nuclear Fusion Research, 1996 (International Atomic Energy Agency, Vienna, 1997), Vol. 1, p. 3], are compared. These comparisons provide information on effects of differences in the physics content of the various models and on the fusion-relevant figures of merit of plasma performance predicted by the models. Many of the comparisons are undertaken for a simplified plasma model and geometry which is an idealization of the plasma conditions and geometry in a Doublet III-D [Plasma Physics and Controlled Nuclear Fusion Research, 1986 (International Atomic Energy Agency, Vienna, 1987), Vol. 1, p. 159] high confinement (H-mode) experiment. Most of the models show good agreements in their predictions and assumptions for the linear growth rates and frequencies. There are some differences associated with different equilibria. However, there are significant differences in the transport levels between the models. The causes of some of the differences are examined in some detail, with particular attention to numerical convergence in the turbulence simulations (with respect to simulation mesh size, system size and, for particle-based simulations, the particle number). The implications for predictions of fusion plasma performance are also discussed.

953 citations

Journal ArticleDOI
07 Feb 1992-Cell
TL;DR: The brahma (brm) gene encodes a 1638 residue protein that is similar to SNF2/SWI2, a protein involved in transcriptional activation in yeast, suggesting possible models for the role of brm in the transcriptionalactivation of homeotic genes.

951 citations

Journal ArticleDOI
TL;DR: In the years ahead, climate warming will aggravate eutrophication in lakes receiving point sources of nutrients, as a result of increasing water residence times, which will increasingly favor the replacement of diatoms by nitrogen-fixing Cyanobacteria as mentioned in this paper.
Abstract: Major advances in the scientific understanding and management of eutrophication have been made since the late 1960s. The control of point sources of phosphorus reduced algal blooms in many lakes. Diffuse nutrient sources from land use changes and urbanization in the catchments of lakes have proved possible to control but require many years of restoration efforts. The importance of water residence time to eutrophication has been recognized. Changes in aquatic communities contribute to eutrophication via the trophic cascade, nutrient stoichiometry, and transport of nutrients from benthic to pelagic regions. Overexploitation of piscivorous fishes appears to be a particularly common amplifier of eutrophication. Internal nutrient loading can be controlled by reducing external loading, although the full response of lakes may take decades. In the years ahead, climate warming will aggravate eutrophication in lakes receiving point sources of nutrients, as a result of increasing water residence times. Decreased silica supplies from dwindling inflows may increasingly favor the replacement of diatoms by nitrogen-fixing Cyanobacteria. Increases in transport of nitrogen by rivers to estuaries and coastal oceans have followed increased use of nitrogen in agriculture and increasing emissions to the atmosphere. Our understanding of eutrophication and its management has evolved from simple control of nutrient sources to recognition that it is often a cumulative effects problem that will require protection and restoration of many features of a lake's community and its catchment.

950 citations

Journal ArticleDOI
TL;DR: The occurrence of adverse events after presentation with acute coronary syndromes is affected by multiple factors and these factors should be considered in the clinical decision-making process.
Abstract: BACKGROUND: Appropriate treatment policies should include an accurate estimate of a patient's baseline risk. Risk modeling to date has been underutilized in patients with acute coronary syndromes without persistent ST-segment elevation. METHODS AND RESULTS: We analyzed the relation between baseline characteristics and the 30-day incidence of death and the composite of death or myocardial (re)infarction in 9461 patients with acute coronary syndromes without persistent ST-segment elevation enrolled in the PURSUIT trial [Platelet glycoprotein IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin (eptifibatide) Therapy]. Variables examined included demographics, history, hemodynamic condition, and symptom duration. Risk models were created with multivariable logistic regression and validated by bootstrapping techniques. There was a 3.6% mortality rate and 11.4% infarction rate by 30 days. More than 20 significant predictors for mortality and for the composite end point were identified. The most important baseline determinants of death were age (adjusted chi(2)=95), heart rate (chi(2)=32), systolic blood pressure (chi(2)=20), ST-segment depression (chi(2)=20), signs of heart failure (chi(2)=18), and cardiac enzymes (chi(2)=15). Determinants of mortality were generally also predictive of death or myocardial (re)infarction. Differences were observed, however, in the relative prognostic importance of predictive variables for mortality alone or the composite end point; for example, sex was a more important determinant of the composite end point (chi(2)=21) than of death alone (chi(2)=10). The accuracy of the prediction of the composite end point was less than that of mortality (C-index 0.67 versus 0.81). CONCLUSIONS: The occurrence of adverse events after presentation with acute coronary syndromes is affected by multiple factors. These factors should be considered in the clinical decision-making process.

948 citations


Authors

Showing all 66027 results

NameH-indexPapersCitations
Salim Yusuf2311439252912
Yi Chen2174342293080
Robert M. Califf1961561167961
Douglas R. Green182661145944
Russel J. Reiter1691646121010
Jiawei Han1681233143427
Jaakko Kaprio1631532126320
Tobin J. Marks1591621111604
Josef M. Penninger154700107295
Subir Sarkar1491542144614
Gerald M. Edelman14754569091
Rinaldo Bellomo1471714120052
P. Sinervo138151699215
David A. Jackson136109568352
Andreas Warburton135157897496
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20241
2023234
20221,084
20219,315
20208,831
20198,177