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Institution

University of Alcalá

EducationAlcalá de Henares, Spain
About: University of Alcalá is a education organization based out in Alcalá de Henares, Spain. It is known for research contribution in the topics: Population & Receptor. The organization has 10795 authors who have published 20718 publications receiving 410089 citations. The organization is also known as: University of Alcala & University of Alcala de Henares.


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Journal ArticleDOI
01 Jan 1995-Urology
TL;DR: The present study validates the prognostic significance of such a distinction both by Mantel-Haenszel life table method and Cox's regression analysis and proves the depth of tumor infiltration can be assessed in a considerable proportion of Stage T1 bladder neoplasms.

134 citations

Journal ArticleDOI
TL;DR: In this article, a detection method for long-lasting and large-scale summer heatwaves, using a local, climatological 99th percentile threshold, based on present-climate (1976-2005) daily SST.
Abstract: Extreme ocean warming events, known as marine heatwaves (MHWs), have been observed to perturb significantly marine ecosystems and fisheries around the world. Here, we propose a detection method for long-lasting and large-scale summer MHWs, using a local, climatological 99th percentile threshold, based on present-climate (1976–2005) daily SST. To assess their future evolution in the Mediterranean Sea we use, for the first time, a dedicated ensemble of fully-coupled Regional Climate System Models from the Med-CORDEX initiative and a multi-scenario approach. The models appear to simulate well MHW properties during historical period, despite biases in mean and extreme SST. In response to increasing greenhouse gas forcing, the events become stronger and more intense under RCP4.5 and RCP8.5 than RCP2.6. By 2100 and under RCP8.5, simulations project at least one long-lasting MHW every year, up to three months longer, about 4 times more intense and 42 times more severe than present-day events. They are expected to occur from June-October and to affect at peak the entire basin. Their evolution is found to occur mainly due to an increase in the mean SST, but increased daily SST variability also plays a noticeable role. Until the mid-21st century, MHW characteristics rise independently of the choice of the emission scenario, the influence of which becomes more evident by the end of the period. Further analysis reveals different climate change responses in certain configurations, more likely linked to their driving global climate model rather than to the individual model biases.

134 citations

Journal ArticleDOI
Didac Carmona-Gutierrez1, Maria A. Bauer1, Andreas Zimmermann1, Andrés Aguilera2, Nicanor Austriaco3, Kathryn R. Ayscough4, Rena Balzan5, Shoshana Bar-Nun6, Antonio Barrientos7, Peter Belenky8, Marc Blondel9, Ralf J. Braun10, Michael Breitenbach10, William Wc Burhans11, Sabrina Büttner1, Sabrina Büttner12, Duccio Cavalieri13, Michael Chang14, Katrina Kf Cooper15, Manuela Côrte-Real16, Vítor Costa17, Vítor Costa18, Christophe Cullin19, Ian W. Dawes20, Jörn Dengjel21, Martin Mb Dickman22, Tobias Eisenberg1, Birthe Fahrenkrog23, Nicolas Fasel24, Kai-Uwe Fröhlich1, Ali Gargouri, Sergio Giannattasio25, Paola Goffrini26, Campbell W. Gourlay27, Chris M. Grant28, Michael Mt Greenwood29, Nicoletta Guaragnella25, Thomas Heger, Jürgen J. Heinisch30, Eva Herker31, Johannes M. Herrmann32, Sebastian J. Hofer1, Antonio Jiménez-Ruiz33, Helmut Jungwirth1, Katharina Kainz1, Dimitrios P. Kontoyiannis34, Paula Ludovico16, Paula Ludovico35, Stéphen Manon19, Enzo Martegani36, Cristina Mazzoni37, Lynn La Megeney38, Lynn La Megeney39, Christa Meisinger40, Jens Nielsen41, Jens Nielsen42, Thomas Nyström43, Heinz Hd Osiewacz44, Tiago Tf Outeiro, Hay-Oak Park45, Tobias Pendl1, Dina Petranovic41, Stéphane Picot46, Peter Polčic47, Ted Powers48, Mark Ramsdale49, Mark Rinnerthaler50, Patrick Rockenfeller27, Patrick Rockenfeller1, Christoph Ruckenstuhl1, Raffael Schaffrath51, María Segovia52, Fedor Ff Severin53, Amir Sharon6, Stephan J. Sigrist54, Cornelia Sommer-Ruck1, Maria João Sousa16, Johan Jm Thevelein55, Karin Thevissen55, Vladimir I. Titorenko56, Michel Mb Toledano57, Mick F. Tuite27, F-Nora Vögtle40, Benedikt Westermann10, Joris Winderickx55, Silke Wissing, Stefan Wölfl58, Zhaojie J Zhang59, Richard Y. Zhao60, Bing Zhou61, Lorenzo Galluzzi62, Lorenzo Galluzzi63, Guido Kroemer, Frank Madeo1 
University of Graz1, Spanish National Research Council2, Providence College3, University of Sheffield4, University of Malta5, Tel Aviv University6, University of Miami7, Brown University8, French Institute of Health and Medical Research9, University of Bayreuth10, Roswell Park Cancer Institute11, Stockholm University12, University of Florence13, University Medical Center Groningen14, Rowan University15, University of Minho16, Instituto de Biologia Molecular e Celular17, University of Porto18, University of Bordeaux19, University of New South Wales20, University of Fribourg21, Texas A&M University22, Université libre de Bruxelles23, University of Lausanne24, National Research Council25, University of Parma26, University of Kent27, University of Manchester28, Royal Military College of Canada29, University of Osnabrück30, Heinrich Pette Institute31, Kaiserslautern University of Technology32, University of Alcalá33, University of Texas MD Anderson Cancer Center34, RMIT University35, University of Milano-Bicocca36, Sapienza University of Rome37, University of Ottawa38, Ottawa Hospital Research Institute39, University of Freiburg40, Chalmers University of Technology41, Technical University of Denmark42, University of Gothenburg43, Goethe University Frankfurt44, Ohio State University45, Centre national de la recherche scientifique46, Comenius University in Bratislava47, University of Minnesota48, University of Exeter49, University of Salzburg50, University of Kassel51, University of Málaga52, Moscow State University53, Free University of Berlin54, Katholieke Universiteit Leuven55, Concordia University56, Université Paris-Saclay57, Heidelberg University58, University of Wyoming59, University of Maryland, Baltimore60, Tsinghua University61, Cornell University62, Paris Descartes University63
TL;DR: Unified criteria for the definition of accidental, regulated, and programmed forms of cell death in yeast based on a series of morphological and biochemical criteria are proposed.
Abstract: Elucidating the biology of yeast in its full complexity has major implications for science, medicine and industry. One of the most critical processes determining yeast life and physiology is cel-lular demise. However, the investigation of yeast cell death is a relatively young field, and a widely accepted set of concepts and terms is still missing. Here, we propose unified criteria for the defi-nition of accidental, regulated, and programmed forms of cell death in yeast based on a series of morphological and biochemical criteria. Specifically, we provide consensus guidelines on the differ-ential definition of terms including apoptosis, regulated necrosis, and autophagic cell death, as we refer to additional cell death rou-tines that are relevant for the biology of (at least some species of) yeast. As this area of investigation advances rapidly, changes and extensions to this set of recommendations will be implemented in the years to come. Nonetheless, we strongly encourage the au-thors, reviewers and editors of scientific articles to adopt these collective standards in order to establish an accurate framework for yeast cell death research and, ultimately, to accelerate the pro-gress of this vibrant field of research.

134 citations

Journal ArticleDOI
TL;DR: In this article, the suitability of Saaty's AHP method for rank reversal has been investigated and it is shown that this undesirable effect does not, per se, invalidate that method, but it does make it necessary to identify the kind of situations in which the method is suitable.
Abstract: The purpose of this short paper is to help clarify some questions which have arisen with respect to the suitability, or even the correctness, of the way Saaty's AHP method handles criteria weights, sometimes causing the rank reversal phenomenon. The position set forth in this paper is that this undesirable effect does not, per se, invalidate that method, but it does make it necessary to identify the kind of situations in which the method is suitable.

133 citations

Journal ArticleDOI
J. Abraham, P. Abreu1, Marco Aglietta2, C. Aguirre  +460 moreInstitutions (69)
TL;DR: In this paper, the Pierre Auger Observatory data were used to establish an upper limit on the diffuse flux of tau neutrinos in the cosmic radiation, and the search procedure to select events induced by tau decays against the background of normal showers induced by cosmic rays was described.
Abstract: Data collected at the Pierre Auger Observatory are used to establish an upper limit on the diffuse flux of tau neutrinos in the cosmic radiation. Earth-skimming nu(tau) may interact in the Earth's crust and produce a tau lepton by means of charged-current interactions. The tau lepton may emerge from the Earth and decay in the atmosphere to produce a nearly horizontal shower with a typical signature, a persistent electromagnetic component even at very large atmospheric depths. The search procedure to select events induced by tau decays against the background of normal showers induced by cosmic rays is described. The method used to compute the exposure for a detector continuously growing with time is detailed. Systematic uncertainties in the exposure from the detector, the analysis, and the involved physics are discussed. No tau neutrino candidates have been found. For neutrinos in the energy range 2x10(17) eV

133 citations


Authors

Showing all 10907 results

NameH-indexPapersCitations
José Luis Zamorano105695133396
Jesús F. San Miguel9752744918
Sebastián F. Sánchez9662932496
Javier P. Gisbert9599033726
Luis M. Ruilope9484197778
Luis M. Garcia-Segura8848427077
Alberto Orfao8559737670
Amadeo R. Fernández-Alba8331821458
Rafael Luque8069328395
Francisco Rodríguez7974824992
Andrea Negri7924235311
Rafael Cantón7857529702
David J. Grignon7830123119
Christophe Baudouin7455322068
Josep M. Argilés7331019675
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20251
20243
202375
2022166
20211,660
20201,532