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Institution

University of Alcalá

EducationAlcalá de Henares, Spain
About: University of Alcalá is a education organization based out in Alcalá de Henares, Spain. It is known for research contribution in the topics: Population & Receptor. The organization has 10795 authors who have published 20718 publications receiving 410089 citations. The organization is also known as: University of Alcala & University of Alcala de Henares.


Papers
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Proceedings ArticleDOI
18 Jun 2016
TL;DR: In this article, the authors proposed a method for performing structural change detection in street-view videos captured by a vehicle-mounted monocular camera over time, motivated by the need for more frequent and efficient updates in the large-scale maps used in autonomous vehicle navigation.
Abstract: We propose a system for performing structural change detection in street-view videos captured by a vehicle-mounted monocular camera over time. Our approach is motivated by the need for more frequent and efficient updates in the large-scale maps used in autonomous vehicle navigation. Our method chains a multi-sensor fusion SLAM and fast dense 3D reconstruction pipeline, which provide coarsely registered image pairs to a deep Deconvolutional Network (DN) for pixel-wise change detection. We investigate two DN architectures for change detection, the first one is based on the idea of stacking contraction and expansion blocks while the second one is based on the idea of Fully Convolutional Networks. To train and evaluate our networks we introduce a new urban change detection dataset which is an order of magnitude larger than existing datasets and contains challenging changes due to seasonal and lighting variations. Our method outperforms existing literature on this dataset, which we make available to the community, and an existing panoramic change detection dataset, demonstrating its wide applicability.

105 citations

Journal ArticleDOI
TL;DR: In this article, the authors developed a spatially explicit patch occupancy model (SPOM) with climate-dependent extinction rates and with colonization rates that depend on both climate and local seed dispersal.
Abstract: Summary 1. The geographic distributions of plant species show marked correlations with the current climate, suggesting that they are likely to shift if climate changes. However, before projecting any such shifts, it is important to establish whether distributions are at equilibrium with the current climate. If they are not, distributional shifts could occur even without climate change, making it difficult to tease apart climate-induced shifts from shifts occurring naturally without climate change. 2. We forecast the geographical distributions of the 10 most common trees occurring in the Iberian Peninsula using a new method that relaxes the species–climate equilibrium assumption implicit in most species distributions models. For each species, we developed a spatially explicit patch occupancy model (SPOM) with climate-dependent extinction rates and with colonization rates that depend on both climate and local seed dispersal. Bayesian methods were used to estimate the colonization, extinction and seed dispersal functions against observed colonization and extinction events recorded in repeat surveys of 46 596 forest plots in the Spanish Forest Inventories (1986–96 and 1997–2007). We then simulated distributional changes between the years 2000–2100. 3. Without climate change, 9 of the 10 species substantially increased in regional frequency. These increases occurred primarily within current ranges, although some species also expanded across their range edges. With climate change, one temperate conifer species and two sub-Mediterranean species would reduce their frequency of occurrence across the studied region, whereas temperate broadleaved species were unaffected and Mediterranean species were either unaffected or increased their frequency of occurrence. 4. Synthesis. The analysis suggests that these species are substantially out of equilibrium, such that abundances and ranges would increase without climate change. Climate change may increase, decrease, stabilize or shift distributions, in a way that can only be understood by comparing predictions against baseline scenarios that account for these non-equilibrium range dynamics.

105 citations

Journal ArticleDOI
TL;DR: Bis(4-aminophenyl)diselenide exhibits the best activity when assayed in infected macrophages and one of the lowest cytotoxic activities against the human cell lines tested, with SI values of 32 and 24 against Jurkat and THP-1 cells, respectively.

105 citations

Journal ArticleDOI
TL;DR: In this paper, the authors use statistical models of yield response functions to address how temperature and precipitation variability affect the crops of a traditional Mediterranean farming system, including cereal, citrus, olives and grapevine.

105 citations

Journal ArticleDOI
TL;DR: The components of the apoptotic execution machinery of these parasites are slowly coming into light, by targeting essential processes and pathways with different apoptogenic agents and inhibitors.
Abstract: Apoptosis is a normal component of the development and health of multicellular organisms. However, apoptosis is now considered a prerogative of unicellular organisms, including the trypanosomatids of the genera Trypanosoma spp. and Leishmania spp., causative agents of some of the most important neglected human diseases. Trypanosomatids show typical hallmarks of apoptosis, although they lack some of the key molecules contributing to this process in metazoans, like caspase genes, Bcl-2 family genes and the TNF-related family of receptors. Despite the lack of these molecules, trypanosomatids appear to have the basic machinery to commit suicide. The components of the apoptotic execution machinery of these parasites are slowly coming into light, by targeting essential processes and pathways with different apoptogenic agents and inhibitors. This review will be confined to the events known to drive trypanosomatid parasites to apoptosis.

105 citations


Authors

Showing all 10907 results

NameH-indexPapersCitations
José Luis Zamorano105695133396
Jesús F. San Miguel9752744918
Sebastián F. Sánchez9662932496
Javier P. Gisbert9599033726
Luis M. Ruilope9484197778
Luis M. Garcia-Segura8848427077
Alberto Orfao8559737670
Amadeo R. Fernández-Alba8331821458
Rafael Luque8069328395
Francisco Rodríguez7974824992
Andrea Negri7924235311
Rafael Cantón7857529702
David J. Grignon7830123119
Christophe Baudouin7455322068
Josep M. Argilés7331019675
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20251
20243
202375
2022166
20211,660
20201,532