University of Alcalá

About: University of Alcalá is a education organization based out in Alcalá de Henares, Spain. It is known for research contribution in the topics: Population & Receptor. The organization has 10795 authors who have published 20718 publications receiving 410089 citations. The organization is also known as: University of Alcala & University of Alcala de Henares.

The prevalence, correlates and treatment of pain in Spain.

Abstract: Objectives:The aims of this paper are to report on the prevalence, correlates and treatment of pain in the adult Spanish population. The analysis also explores the association between the experience of pain and health-related quality of life (HRQoL), employment and productivity, and healthcare resource utilization.Methods:Data are from the internet-based, 2010 National Health and Wellness Survey (NHWS) Spain. The sample was weighted by age and sex to correspond to the 2010 adult Spanish population. All respondents to the NHWS reported on socio-demographic and economic characteristics, medication adherence and major health conditions. They also reported on their HRQoL (the SF-12), their employment status and workplace productivity experience (WPAI instrument) and their healthcare resource utilization. Persons reporting experiencing pain gave details on conditions causing pain, prescription and over the counter (OTC) medication utilization, duration of utilization and satisfaction with medications. ...

Runoff generation and routing on artificial slopes in a Mediterranean–continental environment: the Teruel coalfield, Spain

Abstract: The aim of this study was to identify the mechanisms of runoff generation and routing and their controlling factors at the hillslope scale, on artificial slopes derived from surface coal mining reclamation in a Mediterranean–continental area. Rainfall and runoff at interrill and microcatchment scales were recorded for a year on two slopes with different substrata: topsoil cover and overburden cover. Runoff coefficient and runoff routing from interrill areas to microcatchment outlets were higher in the overburden substratum than in topsoil, and greater in the most developed rill network. Rainfall volume is the major parameter responsible for runoff response on overburden, suggesting that this substratum is very impermeable—at least during the main rainfall periods of the year (late spring and autumn) when the soil surface is sealed. In such conditions, most rainfall input is converted into runoff, regardless of its intensity. Results from artificial rainfall experiments, conducted 3 and 7 years after seeding, confirm the low infiltration capacity of overburden when sealed. The hydrological response shows great seasonal variability on the overburden slope in accordance with soil surface changes over the year. Rainfall volume and intensities (I30, I60) explain runoff at the interrill scale on the topsoil slope, where rainfall experiments demonstrated a typical Hortonian infiltration curve. However, no correlation was found at the microcatchment level, probably because of the loss of functionality of the only rill as ecological succession proceeded. The runoff generation mechanism on the topsoil slope is more homogeneous throughout the year. Runoff connectivity, defined as the ratio between runoff rates recorded at the rill network scale and those recorded at the interrill area scale in every rainfall event, was also greater on the rilled overburden slope, and in the most developed rill network. The dense rill networks of the overburden slope guarantee very effective runoff drainage, regardless of rainfall magnitude. Rills drain overland flow from interrill-sealed areas, reducing the opportunity of reinfiltration in areas not affected by siltation. Runoff generation and routing on topsoil slopes are controlled by grass cover and soil moisture content, whereas on overburden slopes rill network density and soil moisture content are the main controlling factors. Copyright © 2002 John Wiley & Sons, Ltd.

Identification of different chromatin classes in wheat using in situ hybridization with simple sequence repeat oligonucleotides

Abstract: Clusters of four simple sequence repeats (SSRs), AAC, AAG, AG and CAT, have been mapped physically to hexaploid wheat chromosomes; 15—24-bp synthetic oligonucleotides were labelled by random-primer labelling and used as probes for fluorescent in situ hybridization with standard formamide and low-salt conditions. AAC hybridized strongly to the pericentromeric regions and several intercalary sites of all seven chromosomes of the B-genome corresponding to N bands and enabling their identification. Most of the AAC sites also co-localize with AAG, although the strength of the AAC and AAG signal was often different at the same location. Not all heterochromatic bands showed AAC signals and a few AAC sites were detected that are neither AAG nor N band positive, revealing the complex and heterogeneous genome organization of wheat and identifying the four most frequent classes of banded chromatin. Clusters characterised by a high concentration of AG repeats were detected on chromosome arms 3BS, 4BL, 5BS and 5BL, adjacent to AAG sites. The only detectable CAT cluster was found on chromosome arm 3BL, making this oligonucleotide valuable in identifying this particular chromosome. SSR in situ hybridization is useful as a diagnostic tool in cytogenetics and for understanding genome organization in wheat.