scispace - formally typeset
Search or ask a question
Institution

University of Amsterdam

EducationAmsterdam, Noord-Holland, Netherlands
About: University of Amsterdam is a education organization based out in Amsterdam, Noord-Holland, Netherlands. It is known for research contribution in the topics: Population & Context (language use). The organization has 59309 authors who have published 140894 publications receiving 5984137 citations. The organization is also known as: UvA & Universiteit van Amsterdam.


Papers
More filters
Journal ArticleDOI
TL;DR: NS3-specific CD4 T-cell clones from patients with self-limited infection predominantly produced interferon-gamma and may thus support cytotoxic effector mechanisms important for viral clearance.

730 citations

Journal ArticleDOI
TL;DR: Reducing the rate of substrate formation by OGT 918 improves key clinical features of non-neuronopathic Gaucher's disease and justifies further trials in this and other glycosphingolipid storage disorders.

730 citations

Journal ArticleDOI
TL;DR: This report is the first to achieve an international consensus related to the assessment of internet gaming disorder, and describes the intended meaning behind each of the nine DSM-5 criteria for internetGaming disorder.
Abstract: Aims For the first time, the Diagnostic and Statistical Manual for Mental Disorders (DSM-5) introduces non- substance addictions as psychiatric diagnoses. The aims of this paper are to (i) present the main controversies surrounding the decision to include internet gaming disorder, but not internet addiction more globally, as a non-substance addiction in the research appendix of the DSM-5, and (ii) discuss the meaning behind the DSM-5 criteria for internet gaming disorder. The paper also proposes a common method for assessing internet gaming disorder. Although the need for common diagnostic criteria is not debated, the existence of multiple instruments reflect the divergence of opinions in the field regarding how best to diagnose this condition. Methods We convened international experts from European, North and South American, Asian and Australasian countries to discuss and achieve consensus about assessing internet gaming disorder as defined within DSM-5. Results We describe the intended meaning behind each of the nine DSM-5 criteria for internet gaming disorder and present a single item that best reflects each criterion, translated into the 10 main languages of countries in which research on this condition has been conducted. Conclusions Using results from this cross-cultural collaboration, we outline important research directions for understanding and assessing internet gaming disorder. As this field moves forward, it is critical that researchers and clinicians around the world begin to apply a common methodology; this report is the first to achieve an international consensus related to the assessment of internet gaming disorder.

729 citations

Journal ArticleDOI
S. Adrián-Martínez1, M. Ageron2, Felix Aharonian3, Sebastiano Aiello  +243 moreInstitutions (24)
TL;DR: In this article, the main objectives of the KM3NeT Collaboration are (i) the discovery and subsequent observation of high-energy neutrino sources in the Universe and (ii) the determination of the mass hierarchy of neutrinos.
Abstract: The main objectives of the KM3NeT Collaboration are (i) the discovery and subsequent observation of high-energy neutrino sources in the Universe and (ii) the determination of the mass hierarchy of neutrinos. These objectives are strongly motivated by two recent important discoveries, namely: (1) the high-energy astrophysical neutrino signal reported by IceCube and (2) the sizable contribution of electron neutrinos to the third neutrino mass eigenstate as reported by Daya Bay, Reno and others. To meet these objectives, the KM3NeT Collaboration plans to build a new Research Infrastructure consisting of a network of deep-sea neutrino telescopes in the Mediterranean Sea. A phased and distributed implementation is pursued which maximises the access to regional funds, the availability of human resources and the synergistic opportunities for the Earth and sea sciences community. Three suitable deep-sea sites are selected, namely off-shore Toulon (France), Capo Passero (Sicily, Italy) and Pylos (Peloponnese, Greece). The infrastructure will consist of three so-called building blocks. A building block comprises 115 strings, each string comprises 18 optical modules and each optical module comprises 31 photo-multiplier tubes. Each building block thus constitutes a three-dimensional array of photo sensors that can be used to detect the Cherenkov light produced by relativistic particles emerging from neutrino interactions. Two building blocks will be sparsely configured to fully explore the IceCube signal with similar instrumented volume, different methodology, improved resolution and complementary field of view, including the galactic plane. One building block will be densely configured to precisely measure atmospheric neutrino oscillations.

729 citations

Journal ArticleDOI
TL;DR: The authors examines three aspects of policy analysis in this changing context: polity, knowledge and intervention, and argues that policy making now often takes place in an "institutional void" where there are no generally accepted rules and norms according to which politics is to be conducted and policy measures are to be agreed upon.
Abstract: How should policy analysis respond to the changing context of policy making? This article examines three aspects of policy analysis in this changing context: polity, knowledge and intervention. It argues that policy making now often takes place in an ‘institutional void’ where there are no generally accepted rules and norms according to which politics is to be conducted and policy measures are to be agreed upon. More than before, solutions for pressing problems transgress the sovereignty of specific polities. Furthermore, the role of knowledge changes as the relationship between science and society has changed: scientific expertise is now negotiated rather than simply accepted. And, with the weakening of the state, it is far less obvious that the government is the sole actor to intervene in policy making. This article calls for a reconsideration of the analysis of policy making in the light of this changing context. Based on a contextual perspective it calls for a revitalization of the commitments of Harold Lasswell toward a policy science of democracy by proposing a new ‘deliberative’ policy analysis.

729 citations


Authors

Showing all 59759 results

NameH-indexPapersCitations
Richard A. Flavell2311328205119
Scott M. Grundy187841231821
Stuart H. Orkin186715112182
Kenneth C. Anderson1781138126072
David A. Weitz1781038114182
Dorret I. Boomsma1761507136353
Brenda W.J.H. Penninx1701139119082
Michael Kramer1671713127224
Nicholas J. White1611352104539
Lex M. Bouter158767103034
Wolfgang Wagner1562342123391
Jerome I. Rotter1561071116296
David Cella1561258106402
David Eisenberg156697112460
Naveed Sattar1551326116368
Network Information
Related Institutions (5)
University College London
210.6K papers, 9.8M citations

94% related

University of Edinburgh
151.6K papers, 6.6M citations

94% related

University of Pennsylvania
257.6K papers, 14.1M citations

94% related

Columbia University
224K papers, 12.8M citations

94% related

University of Pittsburgh
201K papers, 9.6M citations

94% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023198
2022699
20219,646
20208,532
20197,821
20186,407