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Institution

University of Arizona

EducationTucson, Arizona, United States
About: University of Arizona is a education organization based out in Tucson, Arizona, United States. It is known for research contribution in the topics: Population & Galaxy. The organization has 63805 authors who have published 155998 publications receiving 6854915 citations. The organization is also known as: UA & U of A.
Topics: Population, Galaxy, Stars, Redshift, Star formation


Papers
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Journal ArticleDOI
15 Dec 2004-Sleep
TL;DR: The lack of standardized operational research diagnostic criteria (RDC) for their definition has, in turn, led to inconsistent research findings for most phenotypes largely due to the variable definitions used for their ascertainment as discussed by the authors.
Abstract: Insomnia is a highly prevalent, often debilitating, and economically burdensome form of sleep disturbance caused by various situational, medical, emotional, environmental and behavioral factors. Although several consensually-derived nosologies have described numerous insomnia phenotypes, research concerning these phenotypes has been greatly hampered by a lack of widely accepted operational research diagnostic criteria (RDC) for their definition. The lack of RDC has, in turn, led to inconsistent research findings for most phenotypes largely due to the variable definitions used for their ascertainment. Given this problem, the American Academy of Sleep Medicine (AASM) commissioned a Work Group (WG) to review the literature and identify those insomnia phenotypes that appear most valid and tenable. In addition, this WG was asked to derive standardized RDC for these phenotypes and recommend assessment procedures for their ascertainment. This report outlines the WG's findings, the insomnia RDC derived, and research assessment procedures the WG recommends for identifying study participants who meet these RDC.

925 citations

Journal ArticleDOI
TL;DR: A quantitative model of the aberrant cell cycle regulation in MCL is proposed that provides a rationale for the design of cell cycle inhibitor therapy in this malignancy.

923 citations

Journal ArticleDOI
TL;DR: Evidence for and against adaptive explanations for antagonistic crosstalk are examined, its phylogenetic origins are traced, and a hypothesis-testing framework for future research on the adaptive significance of SA-JA crosStalk is provided.

923 citations

Journal ArticleDOI
TL;DR: In this article, the authors investigated the relationship between the characteristic broad-line region size (RBLR) and the Balmer emission-line, X-ray, UV, and optical continuum luminosities.
Abstract: We reinvestigate the relationship between the characteristic broad-line region size (RBLR) and the Balmer emission-line, X-ray, UV, and optical continuum luminosities. Our study makes use of the best available determinations of RBLR for a large number of active galactic nuclei (AGNs) from Peterson et al. Using their determinations of RBLR for a large sample of AGNs and two different regression methods, we investigate the robustness of our correlation results as a function of data subsample and regression technique. Although small systematic differences were found depending on the method of analysis, our results are generally consistent. Assuming a power-law relation RBLR ∝ Lα, we find that the mean best-fitting α is about 0.67 ± 0.05 for the optical continuum and the broad Hβ luminosity, about 0.56 ± 0.05 for the UV continuum luminosity, and about 0.70 ± 0.14 for the X-ray luminosity. We also find an intrinsic scatter of ~40% in these relations. The disagreement of our results with the theoretical expected slope of 0.5 indicates that the simple assumption of all AGNs having on average the same ionization parameter, BLR density, column density, and ionizing spectral energy distribution is not valid and there is likely some evolution of a few of these characteristics along the luminosity scale.

923 citations

Journal ArticleDOI
TL;DR: The structures of over 230 metabolites isolated and characterized from over 70 plant-associated microbial strains during the past four years are presented with information on their hosts, culture conditions, and biological activities.
Abstract: A growing body of evidence suggests that plant-associated microorganisms, especially endophytic and rhizosphere bacteria and fungi, represent a huge and largely untapped resource of natural products with chemical structures that have been optimized by evolution for biological and ecological relevance. A diverse array of bioactive small molecule natural products has been encountered in these microorganisms. The structures of over 230 metabolites isolated and characterized from over 70 plant-associated microbial strains during the past four years are presented with information on their hosts, culture conditions, and biological activities. Some significant biological and ecological implications of their occurrence are also reviewed.

922 citations


Authors

Showing all 64388 results

NameH-indexPapersCitations
Simon D. M. White189795231645
Julie E. Buring186950132967
David H. Weinberg183700171424
Richard Peto183683231434
Xiaohui Fan183878168522
Dennis S. Charney179802122408
Daniel J. Eisenstein179672151720
David Haussler172488224960
Carlos S. Frenk165799140345
Jian-Kang Zhu161550105551
Tobin J. Marks1591621111604
Todd Adams1541866143110
Jane A. Cauley15191499933
Wei Zheng1511929120209
Daniel L. Schacter14959290148
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023205
2022994
20217,006
20207,325
20196,716
20186,375