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Institution

University of Arizona

EducationTucson, Arizona, United States
About: University of Arizona is a education organization based out in Tucson, Arizona, United States. It is known for research contribution in the topics: Population & Galaxy. The organization has 63805 authors who have published 155998 publications receiving 6854915 citations. The organization is also known as: UA & U of A.
Topics: Population, Galaxy, Star formation, Redshift, Planet


Papers
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Journal ArticleDOI
TL;DR: The Cosmic Evolution Survey (COSMOS) as mentioned in this paper is designed to probe the correlated evolution of galaxies, star formation, active galactic nuclei (AGNs), and dark matter (DM) with large-scale structure (LSS) over the redshift range z > 0.5-6.
Abstract: The Cosmic Evolution Survey (COSMOS) is designed to probe the correlated evolution of galaxies, star formation, active galactic nuclei (AGNs), and dark matter (DM) with large-scale structure (LSS) over the redshift range z > 0.5-6. The survey includes multiwavelength imaging and spectroscopy from X-ray-to-radio wavelengths covering a 2 deg^2 area, including HST imaging. Given the very high sensitivity and resolution of these data sets, COSMOS also provides unprecedented samples of objects at high redshift with greatly reduced cosmic variance, compared to earlier surveys. Here we provide a brief overview of the survey strategy, the characteristics of the major COSMOS data sets, and a summary the science goals.

1,848 citations

Journal ArticleDOI
TL;DR: Results indicated that OCBs are related to a number of individual-level outcomes, including managerial ratings of employee performance, reward allocation decisions, and a variety of withdrawal-related criteria, and some evidence that O CBs are causally related to these criteria is provided.
Abstract: Although one of the main reasons for the interest in organizational citizenship behaviors (OCBs) is the potential consequences of these behaviors, no study has been reported that summarizes the research regarding the relationships between OCBs and their outcomes. Therefore, the purpose of this study is to provide a meta-analytic examination of the relationships between OCBs and a variety of individual- and organizational-level outcomes. Results, based on 168 independent samples (N 51,235 individuals), indicated that OCBs are related to a number of individual-level outcomes, including managerial ratings of employee performance, reward allocation decisions, and a variety of withdrawal-related criteria (e.g., employee turnover intentions, actual turnover, and absenteeism). In addition, OCBs were found to be related (k 38; N 3,611 units) to a number of organizational-level outcomes (e.g., productivity, efficiency, reduced costs, customer satisfaction, and unit-level turnover). Of interest, somewhat stronger relationships were observed between OCBs and unit-level performance measures in longitudinal studies than in cross-sectional studies, providing some evidence that OCBs are causally related to these criteria. The implications of these findings for both researchers and practitioners are discussed.

1,847 citations

Journal ArticleDOI
TL;DR: Evidence suggests that aprotein kinase complex consisting of the myristoylated calcium-binding protein SOS3 and the serine/threonine protein kinase SOS2 is activated by a salt-stress-elicited calcium signal, which phosphorylates and activates various ion transporters, such as the plasma membrane Na(+)/H(+) antiporter SOS1.

1,843 citations

Journal ArticleDOI
TL;DR: T-VEC is the first oncolytic immunotherapy to demonstrate therapeutic benefit against melanoma in a phase III clinical trial and represents a novel potential therapy for patients with metastatic melanoma.
Abstract: Purpose Talimogene laherparepvec (T-VEC) is a herpes simplex virus type 1‐derived oncolytic immunotherapy designed to selectively replicate within tumors and produce granulocyte macrophage colony-stimulating factor (GM-CSF) to enhance systemic antitumor immune responses. T-VEC was compared with GM-CSF in patients with unresected stage IIIB to IV melanoma in a randomized open-label phase III trial. Patients and Methods Patients with injectable melanoma that was not surgically resectable were randomly assigned at a two-to-one ratio to intralesional T-VEC or subcutaneous GM-CSF. The primary end point was durable response rate (DRR; objective response lasting continuously 6 months) per independent assessment. Key secondary end points included overall survival (OS) and overall response rate. Results Among 436 patients randomly assigned, DRR was significantly higher with T-VEC (16.3%; 95% CI, 12.1% to 20.5%) than GM-CSF (2.1%; 95% CI, 0% to 4.5%]; odds ratio, 8.9; P .001). Overall response rate was also higher in the T-VEC arm (26.4%; 95% CI, 21.4% to 31.5% v 5.7%; 95% CI, 1.9% to 9.5%). Median OS was 23.3 months (95% CI, 19.5 to 29.6 months) with T-VEC and 18.9 months (95% CI, 16.0 to 23.7 months) with GM-CSF (hazard ratio, 0.79; 95% CI, 0.62 to 1.00; P .051). T-VEC efficacy was most pronounced in patients with stage IIIB, IIIC, or IVM1a disease and in patients with treatment-naive disease. The most common adverse events (AEs) with T-VEC were fatigue, chills, and pyrexia. The only grade 3 or 4 AE occurring in 2% of T-VEC‐treated patients was cellulitis (2.1%). No fatal treatment-related AEs occurred.

1,815 citations

Journal ArticleDOI
TL;DR: In this article, an almost independent constraint on the ratio of distances D-V(0.275) = 0.1390 +/- 0.0037 (2.7 per cent accuracy), where r(s) is the comoving sound horizon at the baryon-drag epoch, DV(z) equivalent to [(1 + z)D(A)(2)cz/H(z)](1/3), D-A(z), is the angular diameter distance and H(z).
Abstract: The spectroscopic Sloan Digital Sky Survey (SDSS) Data Release 7 (DR7) galaxy sample represents the final set of galaxies observed using the original SDSS target selection criteria. We analyse the clustering of galaxies within this sample, including both the luminous red galaxy and main samples, and also include the 2-degree Field Galaxy Redshift Survey data. In total, this sample comprises 893 319 galaxies over 9100 deg(2). Baryon acoustic oscillations (BAO) are observed in power spectra measured for different slices in redshift; this allows us to constrain the distance-redshift relation at multiple epochs. We achieve a distance measure at redshift z = 0.275, of r(s)(z(d))/D-V(0.275) = 0.1390 +/- 0.0037 (2.7 per cent accuracy), where r(s)(z(d)) is the comoving sound horizon at the baryon-drag epoch, D-V(z) equivalent to [(1 + z)(2)D(A)(2)cz/H(z)](1/3), D-A(z) is the angular diameter distance and H(z) is the Hubble parameter. We find an almost independent constraint on the ratio of distances D-V(0.35)/D-V(0.2) = 1.736 +/- 0.065, which is consistent at the 1.1 sigma level with the best-fitting Lambda cold dark matter model obtained when combining our z = 0.275 distance constraint with the Wilkinson Microwave Anisotropy Probe 5-year (WMAP5) data. The offset is similar to that found in previous analyses of the SDSS DR5 sample, but the discrepancy is now of lower significance, a change caused by a revised error analysis and a change in the methodology adopted, as well as the addition of more data. Using WMAP5 constraints on Omega(b)h(2) and Omega(c) h(2), and combining our BAO distance measurements with those from the Union supernova sample, places a tight constraint on Omega(m) = 0.286 +/- 0.018 and H-0 = 68.2 +/- 2.2 km s(-1) Mpc(-1) that is robust to allowing Omega(k) not equal 0 and omega not equal -1. This result is independent of the behaviour of dark energy at redshifts greater than those probed by the BAO and supernova measurements. Combining these data sets with the full WMAP5 likelihood constraints provides tight constraints on both Omega(k) = -0.006 +/- 0.008 and omega = -0.97 +/- 0.10 for a constant dark energy equation of state.

1,814 citations


Authors

Showing all 64388 results

NameH-indexPapersCitations
Simon D. M. White189795231645
Julie E. Buring186950132967
David H. Weinberg183700171424
Richard Peto183683231434
Xiaohui Fan183878168522
Dennis S. Charney179802122408
Daniel J. Eisenstein179672151720
David Haussler172488224960
Carlos S. Frenk165799140345
Jian-Kang Zhu161550105551
Tobin J. Marks1591621111604
Todd Adams1541866143110
Jane A. Cauley15191499933
Wei Zheng1511929120209
Daniel L. Schacter14959290148
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023205
2022987
20217,005
20207,325
20196,716
20186,375