University of Basel

About: University of Basel is a education organization based out in Basel, Basel-Stadt, Switzerland. It is known for research contribution in the topics: Population & Gene. The organization has 25084 authors who have published 52975 publications receiving 2388002 citations. The organization is also known as: Universität Basel & Basel University.

A Curious Milky Way Satellite in Ursa Major

Abstract: In this Letter, we study a localized stellar overdensity in the constellation of Ursa Major, first identified in Sloan Digital Sky Survey (SDSS) data and subsequently followed up with Subaru imaging. Its color-magnitude diagram (CMD) shows a well-defined subgiant branch, main sequence, and turnoff, from which we estimate a distance of ~30 kpc and a projected size of ~250 × 125 pc2. The CMD suggests a composite population with some range in metallicity and/or age. Based on its extent and stellar population, we argue that this is a previously unknown satellite galaxy of the Milky Way, hereby named Ursa Major II (UMa II) after its constellation. Using SDSS data, we find an absolute magnitude of MV ~ -3.8, which would make it the faintest known satellite galaxy. UMa II's isophotes are irregular and distorted with evidence for multiple concentrations; this suggests that the satellite is in the process of disruption.

BUBBLE - an urban boundary layer meteorology project

Abstract: The Basel UrBan Boundary Layer Experiment (BUBBLE) was a year-long experimental effort to investigate in detail the boundary layer structure in the City of Basel, Switzerland. At several sites over different surface types (urban, sub-urban and rural reference) towers up to at least twice the main obstacle height provided turbulence observations at many levels. In addition, a Wind Profiler and a Lidar near the city center were profiling the entire lower troposphere. During an intensive observation period (IOP) of one month duration, several sub-studies on street canyon energetics and satellite ground truth, as well as on urban turbulence and profiling (sodar, RASS, tethered balloon) were performed. Also tracer experiments with near-roof-level release and sampling were performed. In parallel to the experimental activities within BUBBLE, a meso-scale numerical atmospheric model, which contains a surface exchange parameterization, especially designed for urban areas was evaluated and further developed. Finally, the area of the full-scale tracer experiment which also contains several sites of other special projects during the IOP (street canyon energetics, satellite ground truth) is modeled using a very detailed physical scale-model in a wind tunnel. In the present paper details of all these activities are presented together with first results.

The Decapentaplegic morphogen gradient: from pattern formation to growth regulation.

Abstract: Morphogens have been linked to numerous developmental processes, including organ patterning and the control of organ size. Here we review how different experimental approaches have led to an unprecedented level of molecular knowledge about the patterning role of the Drosophila melanogaster morphogen Decapentaplegic (DPP, the homologue of vertebrate bone morphogenetic protein, or BMP), the first validated secreted morphogen. In addition, we discuss how little is known about the role of the DPP morphogen in the control of organ growth and organ size. Continued efforts to elucidate the role of DPP in D. melanogaster is likely to shed light on this fundamental question in the near future.

The fatigue scale for motor and cognitive functions (FSMC) : validation of a new instrument to assess multiple sclerosis-related fatigue

Abstract: Fatigue symptoms are reported by a majority of patients with multiple sclerosis (MS). Reliable assessment, however, is a demanding issue as the symptoms are experienced subjectively and as objective assessment strategies are missing. The objective of this study was to develop and validate a new tool, the Fatigue Scale for Motor and Cognitive Functions (FSMC), for the assessment of MS-related cognitive and motor fatigue. A total of 309 MS patients and 147 healthy controls were included into the validation study. The FSMC was tested against several external criteria (e.g. cognition, motivation, personality and other fatigue scales). The item-analysis and validation procedure showed that the FSMC is highly sensitive and specific in detecting fatigued MS patients, that both subscales significantly differentiated between patients and controls (p 0.91) as well as test-retest reliability (r > 0.80) were high. Cut-off values were determined to classify patients as mildly, moderately or severely fatigued. In conclusion, the FSMC is a new scale that has undergone validation based on a large sample of patients and that provides differential quantification and graduation of cognitive and motor fatigue.