University of Basel

About: University of Basel is a education organization based out in Basel, Basel-Stadt, Switzerland. It is known for research contribution in the topics: Population & Gene. The organization has 25084 authors who have published 52975 publications receiving 2388002 citations. The organization is also known as: Universität Basel & Basel University.

Mapping the world’s free-flowing rivers

Abstract: Free-flowing rivers (FFRs) support diverse, complex and dynamic ecosystems globally, providing important societal and economic services. Infrastructure development threatens the ecosystem processes, biodiversity and services that these rivers support. Here we assess the connectivity status of 12 million kilometres of rivers globally and identify those that remain free-flowing in their entire length. Only 37 per cent of rivers longer than 1,000 kilometres remain free-flowing over their entire length and 23 per cent flow uninterrupted to the ocean. Very long FFRs are largely restricted to remote regions of the Arctic and of the Amazon and Congo basins. In densely populated areas only few very long rivers remain free-flowing, such as the Irrawaddy and Salween. Dams and reservoirs and their up- and downstream propagation of fragmentation and flow regulation are the leading contributors to the loss of river connectivity. By applying a new method to quantify riverine connectivity and map FFRs, we provide a foundation for concerted global and national strategies to maintain or restore them. A comprehensive assessment of the world’s rivers and their connectivity shows that only 37 per cent of rivers longer than 1,000 kilometres remain free-flowing over their entire length.

Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans

Abstract: A Drosophila gene that contains both a paired box and a homeobox and has extensive sequence homology to the mouse Pax-6 (Small eye) gene was isolated and mapped to chromosome IV in a region close to the eyeless locus. Two spontaneous mutations, ey2 and eyR, contain transposable element insertions into the cloned gene and affect gene expression, particularly in the eye primordia. This indicates that the cloned gene encodes ey. The finding that ey of Drosophila, Small eye of the mouse, and human Aniridia are encoded by homologous genes suggests that eye morphogenesis is under similar genetic control in both vertebrates and insects, in spite of the large differences in eye morphology and mode of development.

The type III secretion injectisome.

Abstract: The type III secretion injectisome is a complex nanomachine that allows bacteria to deliver protein effectors across eukaryotic cellular membranes In recent years, significant progress has been made in our understanding of its structure, assembly and mode of operation The principal structural components of the injectisome, from the base located in the bacterial cytosol to the tip of the needle protruding from the cell surface, have been investigated in detail The structures of several constituent proteins were solved at the atomic level and important insights into the assembly process have been gained However, despite the ongoing concerted efforts of molecular and structural biologists, the role of many of the constituent components of this nanomachine remain unknown

Impulse and Self-Control From a Dual-Systems Perspective

Abstract: Though human beings embody a unique ability for planned behavior, they also often act impulsively. This insight may be important for the study of self-control situations in which people are torn between their long-term goals to restrain behavior and their immediate impulses that promise hedonic fulfillment. In the present article, we outline a dual-systems perspective of impulse and self-control and suggest a framework for the prediction of self-control outcomes. This framework combines three elements that, considered jointly, may enable a more precise prediction of self-control outcomes than they do when studied in isolation: impulsive precursors of behavior, reflective precursors, and situational or dispositional boundary conditions. The theoretical and practical utility of such an approach is demonstrated by drawing on recent evidence from several domains of self-control such as eating, drinking, and sexual behavior.