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Institution

University of Basel

EducationBasel, Basel-Stadt, Switzerland
About: University of Basel is a education organization based out in Basel, Basel-Stadt, Switzerland. It is known for research contribution in the topics: Population & Transplantation. The organization has 25084 authors who have published 52975 publications receiving 2388002 citations. The organization is also known as: Universität Basel & Basel University.


Papers
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Journal ArticleDOI
TL;DR: In conclusion, straight sprinting is the most frequent action in goal situations within decisive situations in professional football and should be included in fitness testing and training.
Abstract: The present study aimed to analyse the influence of speed and power abilities in goal situations in professional football. During the second half of the season 2007/08, videos of 360 goals in the first German national league were analysed by visual inspection. For the assisting and the scoring player the situations immediately preceding the goal were evaluated. The observed actions were categorised as: no powerful action, rotation (around the body's centre-line), straight sprint, change-in-direction sprint, jump, or a combination of those categories. Two hundred and ninety-eight (83%) goals were preceded by at least one powerful action of the scoring or the assisting player. Most actions for the scoring player were straight sprints (n = 161, 45% of all analysed goals, P < 0.001) followed by jumps (n = 57, 16%), rotations and change-in-direction sprints (n = 22, 6% each). Most sprints were conducted without an opponent (n = 109, P < 0.001) and without the ball (n = 121, P < 0.001). Similarly, for ...

656 citations

Journal ArticleDOI
25 Feb 1999-Nature
TL;DR: In this paper, the authors reported magnetoresistance measurements on individual multi-walled carbon nanotubes and found that the oscillations are in good agreement with theoretical predictions for the Aharonov-Bohm effect in a hollow conductor with a diameter equal to that of the outermost shell of the nanotube.
Abstract: When electrons pass through a cylindrical electrical conductor aligned in a magnetic field, their wave-like nature manifests itself as a periodic oscillation in the electrical resistance as a function of the enclosed magnetic flux1. This phenomenon reflects the dependence of the phase of the electron wave on the magnetic field, known as the Aharonov–Bohm effect2, which causes a phase difference, and hence interference, between partial waves encircling the conductor in opposite directions. Such oscillations have been observed in micrometre-sized thin-walled metallic cylinders3,4,5 and lithographically fabricated rings6,7,8. Carbon nanotubes9,10 are composed of individual graphene sheets rolled into seamless hollow cylinders with diameters ranging from 1 nm to about 20 nm. They are able to act as conducting molecular wires11,12,13,14,15,16,17,18, making them ideally suited for the investigation of quantum interference at the single-molecule level caused by the Aharonov–Bohm effect. Here we report magnetoresistance measurements on individual multi-walled nanotubes, which display pronounced resistance oscillations as a function of magnetic flux.We find that the oscillations are in good agreement with theoretical predictions for the Aharonov–Bohm effect in a hollow conductor with a diameter equal to that of the outermost shell of the nanotubes. In some nanotubes we also observe shorter-period oscillations, which might result from anisotropic electron currents caused by defects in the nanotube lattice.

656 citations

Journal ArticleDOI
09 Apr 2004-Science
TL;DR: The genome of the filamentous ascomycete Ashbya gossypii provided compelling evidence that the evolution of S. cerevisiae included a whole genome duplication orfusion of two related species and showed which of the duplicated genes lost one copy and which retained both copies.
Abstract: We have sequenced and annotated the genome of the filamentous ascomycete Ashbya gossypii. With a size of only 9.2 megabases, encoding 4718 protein-coding genes, it is the smallest genome of a free-living eukaryote yet characterized. More than 90% of A. gossypii genes show both homology and a particular pattern of synteny with Saccharomyces cerevisiae. Analysis of this pattern revealed 300 inversions and translocations that have occurred since divergence of these two species. It also provided compelling evidence that the evolution of S. cerevisiae included a whole genome duplication or fusion of two related species and showed, through inferred ancient gene orders, which of the duplicated genes lost one copy and which retained both copies.

656 citations

Journal ArticleDOI
TL;DR: A systematic hierarchy of efficient empirical methods to estimate atomization and total energies of molecules and is achieved by a vectorized representation of molecules (so-called Bag of Bonds model) that exhibits strong nonlocality in chemical space.
Abstract: Simultaneously accurate and efficient prediction of molecular properties throughout chemical compound space is a critical ingredient toward rational compound design in chemical and pharmaceutical industries. Aiming toward this goal, we develop and apply a systematic hierarchy of efficient empirical methods to estimate atomization and total energies of molecules. These methods range from a simple sum over atoms, to addition of bond energies, to pairwise interatomic force fields, reaching to the more sophisticated machine learning approaches that are capable of describing collective interactions between many atoms or bonds. In the case of equilibrium molecular geometries, even simple pairwise force fields demonstrate prediction accuracy comparable to benchmark energies calculated using density functional theory with hybrid exchange-correlation functionals; however, accounting for the collective many-body interactions proves to be essential for approaching the “holy grail” of chemical accuracy of 1 kcal/mol ...

655 citations

Journal ArticleDOI
07 Apr 2000-Science
TL;DR: Atomic force microscopy and single-molecule force spectroscopy were combined to image and manipulate purple membrane patches from Halobacterium salinarum, revealing the individuality of the unfolding pathways.
Abstract: Atomic force microscopy and single-molecule force spectroscopy were combined to image and manipulate purple membrane patches from Halobacterium salinarum. Individual bacteriorhodopsin molecules were first localized and then extracted from the membrane; the remaining vacancies were imaged again. Anchoring forces between 100 and 200 piconewtons for the different helices were found. Upon extraction, the helices were found to unfold. The force spectra revealed the individuality of the unfolding pathways. Helices G and F as well as helices E and D always unfolded pairwise, whereas helices B and C occasionally unfolded one after the other. Experiments with cleaved loops revealed the origin of the individuality: stabilization of helix B by neighboring helices.

655 citations


Authors

Showing all 25374 results

NameH-indexPapersCitations
Yang Yang1712644153049
Martin Karplus163831138492
Frank J. Gonzalez160114496971
Paul Emery1581314121293
Matthias Egger152901184176
Don W. Cleveland15244484737
Ashok Kumar1515654164086
Kurt Wüthrich143739103253
Thomas J. Smith1401775113919
Robert Huber13967173557
Peter Robmann135143897569
Ernst Detlef Schulze13367069504
Michael Levine12958655963
Claudio Santoni129102780598
Pablo Garcia-Abia12698978690
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023146
2022552
20213,395
20203,227
20192,984
20182,775