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Institution

University of Basel

EducationBasel, Basel-Stadt, Switzerland
About: University of Basel is a education organization based out in Basel, Basel-Stadt, Switzerland. It is known for research contribution in the topics: Population & Transplantation. The organization has 25084 authors who have published 52975 publications receiving 2388002 citations. The organization is also known as: Universität Basel & Basel University.


Papers
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Journal ArticleDOI
TL;DR: The abundance and composition of microplastics at the surface of the Rhine, one of the largest European rivers, is reported and measures should be implemented to avoid and reduce the pollution with anthropogenic litter in aquatic ecosystems.
Abstract: Microplastics result from fragmentation of plastic debris or are released to the environment as pre-production pellets or components of consumer and industrial products. In the oceans, they contribute to the 'great garbage patches'. They are ingested by many organisms, from protozoa to baleen whales, and pose a threat to the aquatic fauna. Although as much as 80% of marine debris originates from land, little attention was given to the role of rivers as debris pathways to the sea. Worldwide, not a single great river has yet been studied for the surface microplastics load over its length. We report the abundance and composition of microplastics at the surface of the Rhine, one of the largest European rivers. Measurements were made at 11 locations over a stretch of 820 km. Microplastics were found in all samples, with 892,777 particles km (-2) on average. In the Rhine-Ruhr metropolitan area, a peak concentration of 3.9 million particles km (-2) was measured. Microplastics concentrations were diverse along and across the river, reflecting various sources and sinks such as waste water treatment plants, tributaries and weirs. Measures should be implemented to avoid and reduce the pollution with anthropogenic litter in aquatic ecosystems.

646 citations

Journal ArticleDOI
TL;DR: Eosinophilic esophagitis, a primary and chronic disease restricted to the esophagus, leads to persistent dysphagia and structural esophageal alterations but does not impact the nutritional state.

645 citations

Journal ArticleDOI
TL;DR: This work uses efficient protein extraction and sample fractionation, as well as state-of-the-art quantitative mass spectrometry techniques to generate a comprehensive, condition-dependent protein-abundance map for Escherichia coli, uncovering system-wide proteome allocation, expression regulation and post-translational adaptations.
Abstract: Measuring precise concentrations of proteins can provide insights into biological processes. Here we use efficient protein extraction and sample fractionation, as well as state-of-the-art quantitative mass spectrometry techniques to generate a comprehensive, condition-dependent protein-abundance map for Escherichia coli. We measure cellular protein concentrations for 55% of predicted E. coli genes (>2,300 proteins) under 22 different experimental conditions and identify methylation and N-terminal protein acetylations previously not known to be prevalent in bacteria. We uncover system-wide proteome allocation, expression regulation and post-translational adaptations. These data provide a valuable resource for the systems biology and broader E. coli research communities.

644 citations

Journal ArticleDOI
TL;DR: In this paper, high-resolution infra-red thermometry and large numbers of small data loggers were used to assess the spatial and temporal variation of plant surface and ground temperatures as well as snow-melt patterns for 889 plots distributed across three alpine slopes of contrasting exposure.
Abstract: Aim We aim to: (1) explore thermal habitat preferences in alpine plant species across mosaics of topographically controlled micro-habitats; (2) test the predictive value of so-called 'indicator values'; and (3) quantify the shift in micro-habitat conditions under the influence of climate warming. Location Alpine vegetation 2200-2800 m a.s.l., Swiss central Alps. Methods High-resolution infra-red thermometry and large numbers of small data loggers were used to assess the spatial and temporal variation of plant-surface and ground temperatures as well as snow-melt patterns for 889 plots distributed across three alpine slopes of contrasting exposure. These environmental data were then correlated with Landolt indicator values for temperature preferences of different plant species and vegetation units. By simulating a uniform 2 K warming we estimated the changes in abundance of micro-habitat temperatures within the study area. Results Within the study area we observed a substantial variation between micro-habitats in seasonal mean soil temperature (Delta T = 7.2 K), surface temperature (Delta T = 10.5 K) and season length (< 32 days). Plant species with low indicator values for temperature (plants commonly found in cool habitats) grew in significantly colder micro-habitats than plants with higher indicator values found on the same slope. A 2 K warming will lead to the loss of the coldest habitats (3% of current area), 75% of the current thermal micro-habitats will be reduced in abundance (crowding effect) and 22% will become more abundant. Main conclusions Our results demonstrate that the topographically induced mosaics of micro-climatic conditions in an alpine landscape are associated with local plant species distribution. Semi-quantitative plant species indicator values based on expert knowledge and aggregated to community means match measured thermal habitat conditions. Metre-scale thermal contrasts significantly exceed IPCC warming projections for the next 1 years. The data presented here thus indicate a great risk of overestimating alpine habitat losses in isotherm-based model scenarios. While all but the species depending on the very coldest micro-habitats will find thermally suitable 'escape' habitats within short distances, there will be enhanced competition for those cooler places on a given slope in an alpine climate that is 2 K warmer. Yet, due to their topographic variability, alpine landscapes are likely to be safer places for most species than lowland terrain in a warming world.

642 citations

Journal ArticleDOI
TL;DR: Electron microscopic images of the shapes and dimensions of laminin, of fragments of laminationin, and of fibronectin are consistent with the specific molecular weights and with the hydrodynamic properties determined in solution.

641 citations


Authors

Showing all 25374 results

NameH-indexPapersCitations
Yang Yang1712644153049
Martin Karplus163831138492
Frank J. Gonzalez160114496971
Paul Emery1581314121293
Matthias Egger152901184176
Don W. Cleveland15244484737
Ashok Kumar1515654164086
Kurt Wüthrich143739103253
Thomas J. Smith1401775113919
Robert Huber13967173557
Peter Robmann135143897569
Ernst Detlef Schulze13367069504
Michael Levine12958655963
Claudio Santoni129102780598
Pablo Garcia-Abia12698978690
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023146
2022552
20213,395
20203,227
20192,984
20182,775