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Institution

University of Bath

EducationBath, Bath and North East Somerset, United Kingdom
About: University of Bath is a education organization based out in Bath, Bath and North East Somerset, United Kingdom. It is known for research contribution in the topics: Population & Photonic-crystal fiber. The organization has 15830 authors who have published 39608 publications receiving 1358769 citations. The organization is also known as: Bath University.


Papers
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Journal ArticleDOI
TL;DR: In this paper, a review of the generation, occurrence and action of singlet oxygen in plant tissue is presented, focusing on its formation from triplet sensitizers and its reactivity with molecules of biological importance such as lipids and amino acids.

336 citations

Journal ArticleDOI
27 Oct 2005-Nature
TL;DR: It is shown that ssm is a point mutation in the Hira gene, thus demonstrating that the histone chaperone protein HIRA is required for nucleosome assembly during sperm nucleus decondensation, and that nucleosomes containing H3.3, and not H3, are specifically assembled in paternal Drosophila chromatin before the first round of DNA replication.
Abstract: In sexually reproducing animals, a crucial step in zygote formation is the decondensation of the fertilizing sperm nucleus into a DNA replication-competent male pronucleus. Genome-wide nucleosome assembly on paternal DNA implies the replacement of sperm chromosomal proteins, such as protamines, by maternally provided histones1,2. This fundamental process is specifically impaired in sesame (ssm), a unique Drosophila maternal effect mutant that prevents male pronucleus formation3. Here we show that ssm is a point mutation in the Hira gene, thus demonstrating that the histone chaperone protein HIRA is required for nucleosome assembly during sperm nucleus decondensation. In vertebrates, HIRA has recently been shown to be critical for a nucleosome assembly pathway independent of DNA synthesis that specifically involves the H3.3 histone variant4,5. We also show that nucleosomes containing H3.3, and not H3, are specifically assembled in paternal Drosophila chromatin before the first round of DNA replication. The exclusive marking of paternal chromosomes with H3.3 represents a primary epigenetic distinction between parental genomes in the zygote, and underlines an important consequence of the critical and highly specialized function of HIRA at fertilization.

335 citations

Journal ArticleDOI
TL;DR: It is confirmed that sonoporation is a means with which to achieve macromolecule delivery into cells, and the phenomenon of ultrasound induction of transient pores in the cell membrane is characterizes in some detail.

333 citations

Journal ArticleDOI
TL;DR: The current understanding of the mechanism of action of these immune-related lncRNAs is reviewed, their impact on physiological and pathological processes are discussed, and important areas of inquiry at the intersection between immunology and lncRNA biology are highlighted.

333 citations

Journal ArticleDOI
TL;DR: Luxury retail draws on the principles of art and magic to assemble the charismatic persona of the creative director and to diffuse his aesthetic ideology to the brand as mentioned in this paper, and it enlists magical and aesthetic principles within and without the store to achieve these ends.

333 citations


Authors

Showing all 16056 results

NameH-indexPapersCitations
Michael Grätzel2481423303599
Brenda W.J.H. Penninx1701139119082
Amartya Sen149689141907
Gilbert Laporte12873062608
Andre K. Geim125445206833
Matthew Jones125116196909
Benoît Roux12049362215
Stephen Mann12066955008
Bruno S. Frey11990065368
Raymond A. Dwek11860352259
David Cutts11477864215
John Campbell107115056067
David Chandler10742452396
Peter H.R. Green10684360113
Huajian Gao10566746748
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202386
2022404
20212,474
20202,371
20192,144
20181,972