University of Bath

About: University of Bath is a education organization based out in Bath, Bath and North East Somerset, United Kingdom. It is known for research contribution in the topics: Population & Context (language use). The organization has 15830 authors who have published 39608 publications receiving 1358769 citations. The organization is also known as: Bath University.

The extracellular matrix: Structure, composition, age-related differences, tools for analysis and applications for tissue engineering:

Abstract: The extracellular matrix is a structural support network made up of diverse proteins, sugars and other components. It influences a wide number of cellular processes including migration, wound healing and differentiation, all of which is of particular interest to researchers in the field of tissue engineering. Understanding the composition and structure of the extracellular matrix will aid in exploring the ways the extracellular matrix can be utilised in tissue engineering applications especially as a scaffold. This review summarises the current knowledge of the composition, structure and functions of the extracellular matrix and introduces the effect of ageing on extracellular matrix remodelling and its contribution to cellular functions. Additionally, the current analytical technologies to study the extracellular matrix and extracellular matrix–related cellular processes are also reviewed.

Variations in self-determination across the stages of change for exercise in adults.

Abstract: This study explored the relationship between self-determination in the regulation of exercise behavior and stage of change for exercise. Deci and Ryan (1985, 1990) outlined a continuum of behavioral regulation that ranges from non-self-determined regulation (external regulation) to completely self-determined regulation (intrinsic regulation). Prochaska and DiClemente (1984) outlined five stages of behavior change that range from no thoughts of changing (precontemplation) to maintenance of change (maintenance). In our study, 314 individuals completed measures of regulation in exercise behavior and stage of change for exercise. Discriminant function analysis revealed that those in the latter stages of change were more self-determined in their behavioral regulation than those in the early stages of change. An analysis of variance indicated that self-determination increased from the lower to the upper stages of change. Results endorse the importance of motivational considerations in understanding the change process.

Manufacturer-Overseas Distributor Relations and export Performance

Abstract: The export arrangement which makes use of overseas distributors is examined in this article. Although this method is important for many manufacturers operating in foreign markets there are reservations about the performance levels that are achieved under such arrangements. It is suggested that there is an important link between the performance level achieved and the very nature of the relationship that exists between the manufacturer and overseas distributor. The authors assert also that the nature of the manufacturer-overseas distributor relationship is associated with certain characteristics of the participating companies; namely, their stake in the relationship, their experience, and their uncertainty surrounding the relationship. These propositions are tested and largely corroborated through analysis of data collected from 41 companies in Canada and the UK.

Merging and splitting eigenspace models

Abstract: We present new deterministic methods that, given two eigenspace models-each representing a set of n-dimensional observations-will: 1) merge the models to yield a representation of the union of the sets and 2) split one model from another to represent the difference between the sets. As this is done, we accurately keep track of the mean. Here, we give a theoretical derivation of the methods, empirical results relating to the efficiency and accuracy of the techniques, and three general applications, including the construction of Gaussian mixture models that are dynamically updateable.

Synthetic applications of rhodium catalysed conjugate addition

Abstract: The rhodium catalysed conjugate addition of organometallics to activated alkenes is a powerful synthetic tool for establishing new carbon–carbon bonds often with high stereoselectivity. The introduction of a practical, efficient method for introducing functionalised aryl and alkenyl fragments with predictable stereocontrol has caught the attention of synthetic chemists and emerging examples are growing in number and complexity. In this tutorial review, we document notable advances in the application of rhodium catalysed conjugate addition processes within the context of synthesis of complex molecules and intermediates in drug discovery. The chosen examples illustrate important issues regarding scope, selectivity and reactivity that will help guide the selection of appropriate donor and acceptor to achieve the desired carbon–carbon bond construction when planning new synthetic routes.