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Institution

University of Bedfordshire

EducationLuton, Bedford, United Kingdom
About: University of Bedfordshire is a education organization based out in Luton, Bedford, United Kingdom. It is known for research contribution in the topics: Population & Social work. The organization has 3860 authors who have published 6079 publications receiving 143448 citations. The organization is also known as: University of Luton.


Papers
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Journal ArticleDOI
TL;DR: The efficacy of antimicrobial mixtures that would be classified as synergistic by time-kill methodology was shown to be a natural consequence of combining antimicrobials with non-linear dose responses.
Abstract: AIMS: To demonstrate the effect that non-linear dose responses have on the appearance of synergy in mixtures of antimicrobials. METHODS AND RESULTS: A mathematical model, which allows the prediction of the efficacy of mixtures of antimicrobials with non-linear dose responses, was produced. The efficacy of antimicrobial mixtures that would be classified as synergistic by time-kill methodology was shown to be a natural consequence of combining antimicrobials with non-linear dose responses. CONCLUSIONS: The effectiveness of admixtures of biocides and other antimicrobials with non-linear dose responses can be predicted. If the dose response (or dilution coefficient) of any biocidal component, in a mixture, is other than one, then the time-kill methodology used to ascertain the existence of synergy in antimicrobial combinations is flawed. SIGNIFICANCE AND IMPACT OF THE STUDY: The kinetic model developed allows the prediction of the efficacy of antimicrobial combinations. Combinations of known antimicrobials, which reduce the time taken to achieve a specified level of microbial inactivation, can be easily assessed once the kinetic profile of each component has been obtained. Most patented cases of antimicrobial synergy have not taken into account the possible effect of non-linear dose responses of the component materials. That much of the earlier literature can now be predicted, suggests that future cases will require more thorough proof of the alleged synergy.

45 citations

Journal ArticleDOI
TL;DR: In this paper, the authors provide a conceptual definition of destination management organizations (DMOs) serving as leadership networks in destinations drawing on what is to be called the DMO Leadership Cycle, a guiding framework integrating the perspectives of management, governance and leadership to influence destination development trajectories.
Abstract: Purpose – This paper aims to serve as an introduction to a rather under-researched field. It aims to provide a conceptual definition of destination management organisations (DMOs) serving as leadership networks in destinations drawing on what is to be called the DMO Leadership Cycle – a guiding framework integrating the perspectives of management, governance and leadership to influence destination development trajectories. Design/methodology/approach – A synthesis of the extant literature on destination management and governance, coupled with the latest academic contributions in destination leadership serves to uncover the existence of a gap in the way leadership is seen in the underpinned domain. DMOs are conceptualised and their role in serving as leadership networks in destinations is then critically discussed. Findings – Perspectives of destination management, governance and leadership and their interaction with one another is fundamental to DMOs serving as leadership networks. The paper provides just...

45 citations

Journal ArticleDOI
TL;DR: The results on the percentage incorporation at different times demonstrated that the monoterpene-β-d -glucosides were in a state of rapid metabolic flux as mentioned in this paper.

45 citations

Journal ArticleDOI
20 Jan 2021-Vaccine
TL;DR: Evidence from moderate to high quality studies for improving vaccine uptake included providing information about virus risks and vaccination safety, as well as addressing vaccine misunderstandings, offering vaccination reminders, including vaccination clinic details, and delivering mixed media campaigns across hospitals or communities.

45 citations

Journal ArticleDOI
TL;DR: In this paper, the authors take the strategy of direct nanosecond laser interference lithography technology, and focus on the silicon material to create different well-defined surface structures based on theoretical analysis of the formation of laser interference patterns.

45 citations


Authors

Showing all 3892 results

NameH-indexPapersCitations
Jie Zhang1784857221720
Oscar H. Franco11182266649
Timothy J. Foster9842032338
Christopher P. Denton9567542040
Ian Kimber9162028629
Michael J. Gidley8642024313
David Carling8618645066
Anthony Turner7948924734
Rhys E. Green7828530428
Vijay Kumar Thakur7437517719
Dave J. Adams7328319526
Naresh Magan7240017511
Aedin Cassidy7021817788
David A. Basketter7032516639
Richard C. Strange6724917805
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20236
202248
2021345
2020363
2019323
2018329