scispace - formally typeset
Search or ask a question
Institution

University of Bedfordshire

EducationLuton, Bedford, United Kingdom
About: University of Bedfordshire is a education organization based out in Luton, Bedford, United Kingdom. It is known for research contribution in the topics: Population & Social work. The organization has 3860 authors who have published 6079 publications receiving 143448 citations. The organization is also known as: University of Luton.


Papers
More filters
Journal ArticleDOI
TL;DR: The LLNA is now ready for acceptance as a viable and complete alternative to traditional methods, offering a substantial reduction in animal numbers and refinement opportunities without compromising the standards for the identification of important skin sensitizers.

190 citations

Journal ArticleDOI
TL;DR: The inferred mannan/cellulose sandwich structure may underlie the densification processes which can accompany mannan-containing secondary cell wall formation and promote network formation from galactomannan solutions under conditions where this would not normally occur.

190 citations

Journal ArticleDOI
TL;DR: In this article, a focused review provides updated knowledge regarding the effects of extreme environmental stressors on cognitive function and their biological underpinnings, including the potential mechanisms underpinning these alterations.
Abstract: Cognitive function defines performance in objective tasks that require conscious mental effort. Extreme environments, namely heat, hypoxia, and cold can all alter human cognitive function due to a variety of psychological and/or biological processes. The aims of this Focused Review were to discuss; 1) the current state of knowledge on the effects of heat, hypoxic and cold stress on cognitive function, 2) the potential mechanisms underpinning these alterations, and 3) plausible interventions that may maintain cognitive function upon exposure to each of these environmental stressors. The available evidence suggests that the effects of heat, hypoxia and cold stress on cognitive function are both task and severity dependent. Complex tasks are particularly vulnerable to extreme heat stress, whereas both simple and complex task performance appear to be vulnerable at even at moderate altitudes. Cold stress also appears to negatively impact both simple and complex task performance, however, the research in this area is sparse in comparison to heat and hypoxia. In summary, this focused review provides updated knowledge regarding the effects of extreme environmental stressors on cognitive function and their biological underpinnings. Tyrosine supplementation may help individuals maintain cognitive function in very hot, hypoxic, and/or cold conditions. However, more research is needed to clarify these and other postulated interventions.

189 citations

Book
07 Apr 2004
TL;DR: This paper presents a Cognitive Model of Psychosis, an Introduction to Cognitive Theory and Therapy, and Behavioural Techniques, which outline the techniques used in Therapy to treat Psychosis.
Abstract: Introduction. Preface. An Overview of Psychosis. An Introduction to Cognitive Theory and Therapy. Cognitive Model of Psychosis. Cognitive Assessment of Psychotic Patients. Formulation of the Case. Structure of Therapy. Difficulties in Engagement and the Therapeutic Relationship. Cognitive Techniques. Behavioural Techniques. Schema Change Processes. Negative Symptoms. Problems Associated with Psychosis. Relapse Prevention and Management. Integration of Homework into Therapy. Problems Related to Service Delivery and Context. Appendices.

187 citations

Journal ArticleDOI
TL;DR: The results of the second and final phase of an international trial in which the performance of the assay has been evaluated using seven test materials in five independent laboratories confirm that the local lymph node assay is robust and yields equivalent results when performed independently.

184 citations


Authors

Showing all 3892 results

NameH-indexPapersCitations
Jie Zhang1784857221720
Oscar H. Franco11182266649
Timothy J. Foster9842032338
Christopher P. Denton9567542040
Ian Kimber9162028629
Michael J. Gidley8642024313
David Carling8618645066
Anthony Turner7948924734
Rhys E. Green7828530428
Vijay Kumar Thakur7437517719
Dave J. Adams7328319526
Naresh Magan7240017511
Aedin Cassidy7021817788
David A. Basketter7032516639
Richard C. Strange6724917805
Network Information
Related Institutions (5)
University of Exeter
50.6K papers, 1.7M citations

89% related

University of Nottingham
119.6K papers, 4.2M citations

89% related

University of Birmingham
115.3K papers, 4.3M citations

88% related

Lancaster University
44.5K papers, 1.6M citations

88% related

Queen's University Belfast
55.4K papers, 1.7M citations

88% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20236
202248
2021345
2020363
2019323
2018329